cer 1

ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actinidiae (Psa). ROS inducer 1 induces ROS production in Xanthomonas cells and can be used to study bacterial infections in crops.

C EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via upregulation of C EBP.

Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.

ABCA1 inducer 1, a non-lipid inducer of ABCA1, enhances ABCA1 expression in E3 4FAD mice expressing human APOE 3 4, augments the lipidation of apolipoprotein (APOE), and reverses various Alzheimer's disease (AD) phenotypes without increasing triglycerides.

Tau tracer 1 is a radiopharmaceutical agent designed specifically for visualizing Tau protein aggregates, commonly associated with neurodegenerative diseases. Its primary application lies in the diagnosis of these conditions.

Cholera autoinducer 1 is an autoinducer of Vibrio cholerae. Cholera autoinducer 1 influences chemotaxis in C. elegans [1].

Apoptosis inducer 10 is a potent compound with anti-proliferative activity that induces apoptosis in HeLa (cervical cancer) cells via a mitochondria-dependent endogenous pathway.

Methuosis inducer 1 is a potent methuosis inducer with anticancer activity.

ROS-ERS inducer 1, a type II immunogenic cell death (ICD) inducer, is a Pt(II)-N-heterocyclic carbene (Pt(II)-NHC) complex derived from 4,5-diarylimidazole. It induces endoplasmic reticulum stress (ERS) along with reactive oxygen species (ROS) generation, leading to the release of damage-associated molecular patterns (DAMPs) in HCC cells, showcasing significantly higher anticancer activities than Cisplatin [1].

Apoptosis Inducer 12 (Compound 3z) is a compound that promotes cell death via the mitochondrial pathway and is utilized in cancer research [1].

Apoptosis Inducer 11 (compound 3u) promotes apoptosis via the mitochondrial pathway and elicits a G2 M block alongside a marked reduction in the S phase within non-Hodgkin lymphoma cell lines [1].

Apoptosis Inducer 13 (Compound Ru4) promotes apoptosis in cancer cells while also suppressing their migration and invasion. Additionally, it facilitates the conversion of coenzyme NADH to NAD+, and elevates intracellular ROS levels [1].

ATF3 inducer 1 is an efficient ATF3 inducer with lipid-lowering and anti-hyperglycemic activities. It alleviates glucose intolerance and insulin resistance induced by high-fat diet (HFD) and ameliorates liver steatosis induced by HFD. It can be used for research on obesity.

PROTA CER Degrader-11 (Example 26-1) is an effective degrader of PROTA CER with an IC50 of 0.66 nM. It plays a crucial role in cancer research.

C14 Ceramide (d18:1 14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research.

N-Stearoylsphingosine (Cer(d18:1 18:0)) is an amide compound widely found in eukaryotic organisms that enhances protein phosphatase 2A (PP2A) activity by interfering with the binding of PP2A to PP2A inhibitor 2, leading to dephosphorylation of Akt.N-Stearoylsphingosine is used in prostate cancer research.

C18:1 Ceramide (d18:1 18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant mice and cattle, as well as in plasma and ovarian tissue of patients with advanced ovarian cancer.

C22 Ceramide (d18:1 22:0) (C22 Ceramide), a long-chain ceramide containing behenic acid, is an endogenous bioactive sphingolipid.C22-Ceramide specifically inhibits MCSR and reduces C16 ceramide channel formation in isolated rat liver mitochondria and liposomes.

C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing the F508 deletion (F508del) mutation, enhances cAMP-activated chloride secretion, and suppresses secretion of IL-8 in primary epithelial cells isolated from patients with cystic fibrosis.[3]

C24:1 1-Deoxyceramide (m18:1 24:1(15Z)) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 1-Deoxyceramide (m18:1 24:1(15Z)) is 1246298-58-7.

C12 1-Deoxyceramide (m18:1 12:0) is a lipid molecule that can be used in life science related research. The CAS number of C12 1-Deoxyceramide (m18:1 12:0) is 1246298-54-3.

C16 1-Deoxyceramide (m18:1 16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 1-Deoxyceramide (m18:1 16:0) is 1246298-56-5.

C24:1 dihydro 1-Deoxyceramide (m18:0 24:1) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 dihydro 1-Deoxyceramide (m18:0 24:1) is 1246298-60-1.

C12 3'-sulfo Galactosylceramide (d18:1 12:0) is a lipid molecule that can be used in life science related research. The CAS number of C12 3'-sulfo Galactosylceramide (d18:1 12:0) is 852100-88-0.