centrally — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21793	CGP 35348		GABA Receptor
	CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.		GABA Receptor
T6504	Flupirtine maleate	Katadolon maleate	Potassium Channel , NMDAR , iGluR
	Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener.		Potassium Channel , NMDAR , iGluR
T0015	Mephenesin	Cresoxydiol,Memphenesin,Mephedan,Decontractyl	NMDAR , iGluR
	Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.		NMDAR , iGluR
T1247	Clonidine hydrochloride	Clonidine HCl,Catapres	Adrenergic Receptor
	Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.		Adrenergic Receptor
T2150	Guanfacine hydrochloride	Tenex,Intuniv,Guanfacine	Adrenergic Receptor
	Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.		Adrenergic Receptor
T7579	1-BCP	Piperonylic acid piperidide	GluR , iGluR
	1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.		GluR , iGluR
T1650	Chlorzoxazone	Paraflex,Chlorzoxazon	P450 , Potassium Channel
	Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.		P450 , Potassium Channel
T0201	Meptazinol hydrochloride	Meptazinol HCl	Opioid Receptor
	Meptazinol hydrochloride (Meptazinol HCl) , a unique centrally opioid analgesic, is used as a narcotic antagonist with analgesic properties.		Opioid Receptor
T7045	Clonidine	Nexiclon,Catapres,Kapvay	Adrenergic Receptor
	Clonidine (Kapvay) is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide-scale use for many years, clonidine has not been l...		Adrenergic Receptor
TQ0082	Aticaprant	LY-2456302,CERC-501	Opioid Receptor
	Aticaprant (LY-2456302) (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).		Opioid Receptor
T60107	N-0500 HCl	(-)-Propyl-9-hydroxynaphthoxazine Hydrochloride	Dopamine Receptor
	N-0500 HCl ((-)-Propyl-9-hydroxynaphthoxazine Hydrochloride) is a very potent centrally acting DA receptor agonist. N-0500 HCl is a potent displacer of the specific [3H]DP_x0002_5,6-ADTN binding with IC50 of 3nM.		Dopamine Receptor
T2571	Benactyzine hydrochloride	Neuroleptone,Tranquilline,Amitakon	AChR , AChE
	Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on beh...		AChR , AChE
T21439	Tacrine	CS 12602,Tacrinum,Tetrahydroaminocrine	AChR
	Tacrine (CS 12602) is an indirect cholinergic agonist and centrally acting anticholinesterase. It is approved for the treatment of Alzheimer's disease.		AChR
T1509	Cyclobenzaprine hydrochloride	Cyclobenzaprine HCl,MK130 hydrochloride	5-HT Receptor
	Cyclobenzaprine hydrochloride (MK130 hydrochloride) , a centrally acting muscle relaxant with antidepressant activity, leads to a reduction in muscle spasms.		5-HT Receptor
T16757	Risdiplam	RO7034067,RG7916	DNA/RNA Synthesis
	Risdiplam (RO7034067) (RG7916) is orally administered. Risdiplam is a centrally and peripherally distributed SMN2 pre-mRNA splicing modifier which increases survival motor neuron (SMN) protein levels[1].		DNA/RNA Synthesis
T22689	CP94253 hydrochloride	CP 94253 hydrochloride	Others , 5-HT Receptor
	CP94253 hydrochloride (CP 94253 hydrochloride) is a potent, selective and centrally active agonist of 5-HT1B receptor with Ki of 2 nM. The Kis are 89, 49, 860, and 1600 nM for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors, ...		Others , 5-HT Receptor
T0922	Zoxazolamine	NSC 24995,Contrazole	Others
	Zoxazolamine (NSC-24995) is a uricosuric and muscle relaxant. Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood.		Others
T0470	Nefopam hydrochloride	Fenazoxine hydrochloride,Nefopam HCl	Wnt/beta-catenin , Sodium Channel
	Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.		Wnt/beta-catenin , Sodium Channel
T9857L	Vasopressin acetate	Vasopressin acetate (11000-17-2 Free base)	Endogenous Metabolite
	Vasopressin acetate, a cyclic nonapeptide, is synthesized centrally in the hypothalamus. Vasopressin acetate acts as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors.		Endogenous Metabolite
T68087	Inaperisone		Others
	Inaperisone is a novel centrally acting muscle relaxant that inhibits the voiding reflex. Inaperisone may inhibit the voiding reflex by acting indirectly on GABAB receptors in the brainstem.		Others