c5b

Expression system: E. coli
Length: 679-751, Partial
Activity: Cell Activity

Expression system: HEK293 Cells
Length: 19-1676, Full Length of Mature Protein
Activity: BLI、ELISA

Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 187.36 kDa and the accession number is NP_001726.2.

Expression system: E. coli
Length: 4186-4295, Partial
Activity: Not Tested

Expression system: E. coli
Length: 293-403, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-363, Partial
Activity: Not Tested

The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is O08722.

Expression system: HEK293 Cells
Length: 1-363, Partial
Activity: Not Tested

Expression system: E. coli
Length: 21-202, Full Length of Mature Protein
Activity: Not Tested

Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.