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Results for "

biguanide

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    19
    TargetMol | Inhibitors_Agonists
  • Isotope Products
    2
    TargetMol | Isotope_Products
Biguanide
AI3-52571, AI352571, AI3 52571
T3045056-03-1
Biguanide can reduce oxidative stress in rats with hyperglycemia.
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Poly (hexamethylene biguanide) hydrochloride
T65926
Poly (hexamethylene biguanide) hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T65926.
    7-10 days
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    1-(4-Chlorophenyl)biguanide hydrochloride
    T670454022-81-5
    1-(4-Chlorophenyl)biguanide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67045 and the CAS number is 4022-81-5.
      7-10 days
      Inquiry
      Phenylbiguanide
      PBG, N-Phenylbiguanide, 1-Phenylbiguanide
      T7135102-02-3
      Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)
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      TargetMol | Inhibitor Sale
      1-phenylbiguanide hcl
      Phenylbiguanide hydrochloride
      PDK026955-57-2
      Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.
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      7-10 days
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      TargetMol | Inhibitor Sale
      Poly(hexamethylenebiguanide) hydrochloride
      T7721032289-58-0
      Poly(hexamethylenebiguanide) hydrochloride, serving as an antimicrobial agent, finds applications across various fields including medical, apparel, and household textiles [1].
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      Chlorhexidine
      Chlorhexidinum, Nolvasan, Rotersept
      T100055-56-1
      Chlorhexidine (Rotersept) is a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram-positive bacteria are more negatively charged, they are more sensitive to this agent.
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      Chlorhexidine diacetate
      Hibitane diacetate, Chlorhexidine Acetate, Bactigras
      T1000L56-95-1
      Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
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      Phenformin hydrochloride
      Phenformin HCl, Phenethylbiguanide hydrochloride
      T1453834-28-6
      Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.
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      Buformin hydrochloride
      NSC528218, NSC-528218, NSC 528218
      T200291190-53-0
      Buformin hydrochloride (NSC-528218) is a potent AMPK activator,an oral antidiabetic drug of the biguanide class. Buformin delays the absorption of glucose from the gastrointestinal tract increases insulin sensitivity and glucose uptake into cells and inhibits synthesis of glucose by the liver. Biguanides may antagonize the action of glucagon, thus reducing fasting glucose levels.
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      Picloxydine
      T124705636-92-0
      Picloxydine, a heterocyclic biguanide, possesses antiplaque and antibacterial activity.
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      Phenformin
      Debeone, N-Phenethylbiguanide, Insoral, BRN 1977317, Azucaps
      T20158114-86-3
      Phenformin (BRN 1977317) is a biguanide compound with anticancer and anti-glycemic activity, inhibits skin tumor growth and promotes keratinocyte differentiation and apoptosis.
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      Buformin
      W37,W 37,H 224,W-37
      T23837692-13-7
      Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class. It also inhibits the synthesis of glucose by the liver. Buformin delays absorption of glucose from the gastrointestinal tract increases insulin sensitivity and glucose uptake
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      1-2 weeks
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      Proguanil hydrochloride
      Paludrine hydrochloride, Chlorguanide hydrochloride, Chloroquanil
      T4382637-32-1
      Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite.
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      Chlorhexidine-d8 HCl
      T699952012598-75-1
      Chlorhexidine-d8 is intended for use as an internal standard for the quantification of chlorhexidine by GC- or LC-MS. Chlorhexidine is a bis(biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 μg ml). It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius (MRSP), and methicillin-susceptible S. pseudintermedius (MSSP; MIC90s = 4, 2, 2, and 1 mg L, respectively). Chlorhexidine inhibits growth of E. faecium strains (MICs = 1.2-19.6 μg ml) and C. albicans (MIC = 5.15 μg ml). It generates cations that bind to and destabilize the bacterial cell wall to induce death.6 Chlorhexidine also completely inhibits matrix metalloproteinase-2 (MMP-2) and MMP-9 when used at concentrations of 0.0001 and 0.002%, respectively, in a gelatin degradation assay. Formulations containing chlorhexidine have been used in antisept......
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      6-8 weeks
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      Metformin hydroxy analog 2
      N-Carbonylguanidine
      T8493998026-16-5
      Metformin hydroxy analog 2, an oxidation product of the biguanide metformin (1), represents a chemically transformed variant of the original compound, showcasing a modified molecular structure through the process of oxidation.
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      8-10 weeks
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      V–C6–Bg-PhCl TFA
      T88899
      V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate with broad-spectrum antibacterial activity. It effectively eradicates biofilm-forming Gram-negative and Gram-positive bacteria.
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      Proguanil-d6 HCl
      TMIH-0457
      Proguanil-d6 HCl is a deuterated compound of Proguanil HCl. Proguanil HCl has a CAS number of 637-32-1. Proguanil Hydrochloride is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, proguanil is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite.
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      7-10 days
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