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Results for "

amp/atp

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    21
    TargetMol | Inhibitors_Agonists
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    TargetMol | Compound_Libraries
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Dorsomorphin
Compound C, BML-275
T1977866405-64-3
Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity.
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D-Ribose(mixture of isomers)
D-Ribose, D-(-)-Ribose
T478650-69-1
D-Ribose(mixture of isomers) (D-(-)-Ribose), commonly referred to as simply ribose, is a five-carbon sugar found in all living cells. Ribose is not an essential nutrient because it can be synthesized by almost every tissue in the body from other substances, such as glucose. It is vital for life as a component of DNA, RNA, ATP, ADP, and AMP.
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RGX-202
β-GPA, 3-Guanidinopropionic Acid
T7535353-09-3
RGX-202 (β-GPA) is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coactivator 1α (PGC-1α).
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Dorsomorphin dihydrochloride
Dorsomorphin (Compound C) 2HCl, Compound C dihydrochloride, Compound C 2HCl, BML-275 dihydrochloride, BML-275 2HCl
T61461219168-18-9
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
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Methoxamine hydrochloride
Methoxamine HCl
T099361-16-5
Methoxamine hydrochloride (Methoxamine HCl) is an alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.
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AMP-PCP
T135473469-78-1
AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.
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1-2 weeks
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AMP-PCP disodium
T13547L7414-56-4
AMP-PCP disodium, an ATP analogue, binds to the N-terminal domain of Hsp90 with a Kd value of 3.8 μM, facilitating the formation of an active Hsp90 homodimer.
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6-8 weeks
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8-Chloroadenosine
NSC 354258, 8-Cl-Ado, NSC354258, NSC-354258
T1966134408-14-5
8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine activity is associated with inhibition of the mTOR pathway.8-Chloroadenosine (NSC-354258) is a nucleoside analog; metabolized in vivo to 8-Chloro-ATP. Incorporates into RNA during transcription and inhibits RNA synthesis. Exhibits cytotoxicity in MM.1S, RPMI-8226, and U266 cancer cell lines; induces G2 M cell cycle arrest and mitotic catastrophe in A549 and H1299 cells. 8-Chloroadenosine (NSC-354258) has been shown to deplete ATP and inhibit tumor growth in hematological malignancies as well as in lung and breast cancer cell lines.
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8-Chloro-ATP
8-Cl-cAMP, 8-Cl-ATP, 8-Chloroadenosine 5′-triphosphate, 8-Chloroadenosine 5′-(tetrahydrogen triphosphate), 8-Chloroadenosin-5′-triphosphate
T202217185341-71-3
8-Chloro-ATP (8-Cl-cAMP) is an analog of c-AMP and represents a novel anticancer compound.
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Bempedoic acid
ETC-1002, ETC1002, ETC 1002, ESP-55016
T3625738606-46-7
Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic acid(ETC1002) is absorbed rapidly in the small intestine and enters the liver through cell surface receptors different from those transporters that selectively take up statins. Bempedoic acid(ETC1002) is a regulator of lipid and carbohydrate metabolism.
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Phosphoribosyl pyrophosphate pentasodium
PRPPpentasodium, PRPP pentasodium
T38472108321-05-7
Phosphoribosyl pyrophosphate pentasodium is the sodium salt form of PRPP. PRPP is a phosphoribosyl donor for AMP and GMP synthesis in reactions catalysed by adenine phosphoribosyltransferase and hypoxanthine guanine phosphoribosyltransferase. PRPP is synthesized from ribose-5-phosphate and ATP by PRPP synthetase (EC 2.7.6.1).
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7-10 days
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8-Bromo-AMP
8-Bromoadenosine 5'-monophosphate,8-Bromo-AMP,8-Bromoadenylicacid
T3989023567-96-6
8-Bromo-AMP, also known as 8-Bromoadenosine 5'-monophosphate, is a membrane permeable cAMP analogue. It enhances cardiac recovery from ischemia and reperfusion by elevating ATP, ADP, and total adenine nucleotide concentrations.
    7-10 days
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    2'-Deoxyadenosine-5'-monophosphate
    D-AMP, 2'-Deoxyadenosine 5'-monophosphate
    T4737653-63-4
    2'-Deoxyadenosine-5'-monophosphate (D-AMP) is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucleic acid ATP, or adenosine triphosphate, in which the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose has been removed (hence the deoxy- part of the name). Additionally, the monophosphate of the name indicates that two of the phosphoryl groups of GTP have been removed, most likely by hydrolysis. Deoxyadenosine monophosphate is abbreviated dAMP.
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    Flavin adenine dinucleotide disodium salt
    Flavin Adenine Dinucleotide Disodium, FAD sodium salt, FAD-Na2
    T506784366-81-4
    Flavin adenine dinucleotide disodium salt (FAD sodium salt) is a flavin dinucleotide that is synthesized when the AMP moiety from ATP is transferred onto riboflavin 5'-monophosphate. FAD functions as a coenzyme that facilitates the transfer of electrons by flavoenzymes in oxidation-reduction reactions in cells.
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    7-10 days
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    Poly(A) polymerase
    T799269026-30-6
    Poly(A) polymerase enzymatically adds a polyadenosine tail of 20-200 adenine bases to the 3' end of RNA, a process that involves integrating ATP as AMP. This modification enhances RNA stability and augments mRNA translation efficiency in eukaryotic cells, evidencing the enzyme's high tailing efficiency [1] [2].
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    2-Chloroadenosine-5'-O-diphosphate sodium
    2-chloro ADP
    T8378582927-78-4
    2-Chloroadenosine-5'-O-diphosphate, a purine nucleotide adenosine 5'diphosphate (ADP) derivative, demonstrates multiple biological activities. It promotes aggregation and inhibits cyclic AMP (cAMP) production, triggered by prostaglandin E2 (PGE2), in a concentration-dependent manner within isolated human platelet-rich plasma. Additionally, this compound facilitates the relaxation of precontracted isolated guinea pig taenia coli strips (pD2 = 6.74) and reduces arterial blood pressure in rats. Moreover, 2-Chloroadenosine-5'-O-diphosphate significantly inhibits the ATPase activity of mortalin, a member of the heat shock protein 70 (Hsp70) family, with an apparent Ki of 45.05 µM for the human enzyme.
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    8-10 weeks
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    8-Chloroadenosine-5'-triphosphate sodium
    8-chloro ATP
    T83786793671-47-3
    8-Chloroadenosine-5'-triphosphate (8-chloro ATP), a potent metabolite of the anticancer agent 8-chloro cyclic AMP (cAMP) and a nucleotide derivative, is produced through the biotransformation of 8-chloro cAMP into 8-chloroadenosine, followed by mono- and diphosphate intermediates. Accumulating for up to 12 hours after the administration of 8-chloro cAMP or 8-chloroadenosine, 8-chloro ATP inhibits cell growth, diminishes endogenous ATP levels, and reduces RNA synthesis without affecting DNA synthesis in multiple myeloma cells derived from patients. Moreover, it obstructs topoisomerase II-α-mediated relaxation of supercoiled pUC19 DNA at concentrations ranging from 1.5 to 8 mM and decreases topoisomerase II-α-enhanced ATP hydrolysis by 50% at a concentration of 1 mM in K562 human myelocytic leukemia cells.
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    8-10 weeks
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    IMT1
    Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-, LDC195943(IMT1)
    T88412304621-31-4
    IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.
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    AMP-PNP
    TSW-0010025612-73-1
    AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolyzable ATP analog.
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    7-10 days
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    AMP-PNP lithium hydrate
    TSW-00804
    AMP-PNP lithium hydrate is a non-hydrolyzable ATP analog. It can substitute for ATP in biological research and is not hydrolyzed by intracellular enzymes. In a study on the vitamin B12 transporter BtuCD-F, AMP-PNP was found to block the channels formed by the two BtuCD components of the BtuCD-F complex, thereby preventing the entry of vitamin B12.
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    7-10 days
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    Cyclic AMP sodium
    TYD-0076037839-81-9
    Cyclic AMP (Cyclic adenosine monophosphate) sodium is a derivative of ATP, serving as an intracellular signaling molecule that directs cellular responses to external signals. It functions as a crucial second messenger in numerous biological processes.
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    7-10 days
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