acute lymphoblastic leukemia

L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin.

Terminal deoxyribonucleotidyltransferase (TdT) catalyzes the addition of deoxyribonucleotide triphosphates to the 3' hydroxyl terminus of a DNA chain and introduces N regions at gene segment junctions during V(D)J recombination. It is expressed in immature, pre-B, and pre-T lymphocytes, as well as in acute lymphoblastic leukemia/lymphoma cells.