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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14495 | Baloxavir | Baloxavir acid,S-033447 | Influenza Virus |
Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. | |||
T4686 | Simeprevir | TMC435,TMC-435350,Olysio | HCV Protease , SARS-CoV |
Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM. | |||
T8972 | FIT-039 | Others , DNA/RNA Synthesis , CDK , HSV | |
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a pr... | |||
T5539 | GS-443902 | Nucleoside Antimetabolite/Analog , HCV Protease , SARS-CoV , DNA/RNA Synthesis , RSV , Drug Metabolite | |
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at least 12 weeks | |||
T6833 | Favipiravir | T-705,6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide | Others , SARS-CoV , Influenza Virus , DNA/RNA Synthesis |
Favipiravir (T-705) (T-705), an effective and selective RNA-dependent RNA polymerase inhibitor, are applied to treat influenza virus infections. | |||
T27696 | JTK-109 | JTK109 | HCV Protease |
JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes. | |||
T1501 | Rifabutin | LM-427,Ansamycin | HSP , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Rifabutin (LM-427) inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. Rifabutin is a semisynthetic ansamycin... | |||
T15282 | Filibuvir | PF-00868554 | HCV Protease , DNA/RNA Synthesis |
Filibuvir (PF-00868554) is a selective and noncovalent inhibitor of HCV NS5B RNA-dependent RNA polymerase. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM. | |||
T9617 | RdRP-IN-2 | SARS-CoV | |
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM.It also inhibits Feline coronavirus (FIPV) replication. | |||
T9618 | HeE1-2Tyr | SARS-CoV | |
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 µM) activity in vitro. | |||
TQ0090 | Nesbuvir | HCV-796 | HCV Protease |
Nesbuvir is a selective hepatitis C virus (HCV) nonstructural protein 5B (NS5B) RNA-dependent polymerase inhibitor.Nesbuvir has an IC50 of 9 nM against hepatocellular carcinoma cells containing 1b HCV replicons. | |||
T82568 | DHX9-IN-2 | DNA/RNA Synthesis | |
DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research. | |||
T3489 | Dasabuvir | ABT-333 | HCV Protease |
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra... | |||
T1154 | Rifaximin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting... | |||
T11760 | KIN101 | 3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene | HCV Protease , Influenza Virus , RSV , Antifection |
KIN101 (3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene), an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has antiviral activity against RNA viruses, HCV, and R... | |||
T19836 | 2-Aminopurine | DNA/RNA Synthesis , PKA | |
2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor. | |||
T77520 | AOH1996 | Apoptosis , DNA/RNA Synthesis | |
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its ... | |||
T27260 | Emivirine | MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302 | HIV Protease |
Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1. | |||
T10491L | Galidesivir hydrochloride | BCX 4430 hydrochloride,Immucillin-A hydrochloride | Others |
Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp. | |||
T71748 | RK-0404678 | ||
RK-0404678 is a novel inhibitor of dengue virus NS5 RNA-dependent RNA polymerase (RdRp), inhibiting the DENV type 2 (DENV2) RdRp activities. | |||
T40267 | RdRP-IN-3 | ||
RdRP-IN-3 is a promising anti-influenza drug candidate by inhibiting the activity of RNA-dependent RNA polymerase (RdRp) . | |||
T28538 | Rifamycin SV | ||
Rifamycin SV, a natural antibiotic, blocks RNA-polymerase transcription initiation, modulating ß2m aggregation; inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis. | |||
T21225 | Rifamycin | Rifocin,Rifamycin SV | |
Rifamycin, a natural antibiotic, inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis, leading to the block of RNA-polymerase transcription initiation. | |||
T71825 | BEPP monohydrochloride | ||
BEPP monohydrochloride is a double-strand RNA-dependent protein kinase (PKR) activator. | |||
T27485 | GSK-625433 | ||
GSK-625433, a homochiral inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase, has the ability to inhibit the polymerase of both HCV genotypes 1a and 1b. | |||
T63598 | DENV-IN-4 | ||
DENV-IN-4 is a potent inhibitor of DENV (DENV EC50=4.79 μM, Vero CC50>100 μM, SI>20.9). The antiviral effect was demonstrated by the concentration-dependent reduction of DENV2 expression and the inhibition of RNA-depende... | |||
T10493 | Beclabuvir | BMS-791325 | Others |
Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the HCV NS5B RNA-dependent RNA polymerase. It inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 (IC50 < 28 nM). | |||
T11062 | DmDNA31 | Others | |
dmDNA31 is a rifamycin antibiotic that can inhibit the DNA-dependent RNA polymerase of bacteria and has strong bactericidal activity against Staphylococcus aureus. | |||
T70855 | Favipiravir sodium | ||
Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as o... | |||
T11352 | Galidesivir triphosphate | BCX4430-triphosphate,Immucillin-A triphosphate,BCX6870 | Others |
Galidesivir triphosphate is a substrate for viral RNA-dependent RNA polymerase (RDRP), resulting in termination of viral RNA replication and thus serves as an antiviral. Galidesivir triphosphate inhibits HCV NS5B RNA pol... | |||
T25106 | Aranotin | L53185,Lilly 53185,L 53185,L-53185,Antibiotic A 21101-IL | |
Aranotin is a fungal toxin isolated from Arachniotus aureus with activity against RNA viruses such as poliovirus, coxsackie virus, and rhino- and parainfluenza viruses. Aranotin inhibits viral RNA synthesis by impeding t... | |||
T10491 | Galidesivir | BCX4430,Immucillin-A | Others |
Galidesivir (BCX4430) is a broad-spectrum antiviral compound, an adenosine analog that inhibits viral RNA-dependent RNA polymerase (RdRp) activity.Galidesivir inhibits a wide range of RNA viral pathogens in vitro, and re... | |||
T73323 | RdRP-IN-5 | Influenza Virus | |
RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1]. | |||
T38616 | Teprasiran | QPI-1002 | |
Teprasiran (QPI-1002) is an RNA-based compound that transiently suppresses p53-dependent apoptosis, a process involved in the development of acute kidney injury (AKI). | |||
T41177 | Galidesivir dihydrochloride | BCX 4430 | |
Galidesivir is a viral RNA-dependent RNA polymerase (RdRP) inhibitor and broad spectrum antiviral nucleotide.In vitro, galidesivir displays antiviral activity against a range of RNA viruses, including bunyaviruses, arena... | |||
T72792 | Trans-RdRP-IN-5 | ||
trans-RdRP-IN-5 is a potent influenza virus RNA-dependent RNA polymerase (RdRP) inhibitor. trans-RdRP-IN-5 can be used in research of influenza virus . | |||
T63073 | Cap-dependent endonuclease-IN-19 | ||
Cap-dependent endonuclease-IN-19 is a spirocyclic pyridinone derivative and a potent inhibitor of cap-dependent nucleic acid endonuclease (CEN). cap-dependent endonuclease-IN-19 potently inhibits the RNA polymerase activ... | |||
T38761 | GS-443902 trisodium | GS-441524triphosphatetrisodium,Remdesivirmetabolitetrisodium | |
GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC 50 s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the act... | |||
T62160 | AS-136A | ||
AS-136A is an orally active, non-nucleoside inhibitor of measles virus RNA-dependent RNA polymerase (RdRp) that acts against measles virus (IC50: 2 μM). | |||
T72896 | Cis-RdRP-IN-5 | ||
cis-RdRP-IN-5 is a potent influenza virus RNA-dependent RNA polymerase (RdRP) inhibitor. cis-RdRP-IN-5 can be used in research of influenza virus . | |||
T83251 | 7-51A | Influenza Virus | |
7-51A is an effective inhibitor of the PB2 subunit of the influenza RNA-dependent RNA polymerase (RdRP), with a dissociation constant (K_D) of 1.64 nM as determined by isothermal titration calorimetry (ITC). | |||
T64177 | Cap-dependent endonuclease-IN-2 | ||
Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). Cap-dependent endonuclease-IN-2 significantly inhibits influenza A virus RNA polymerase activity. | |||
T16749 | Rifalazil | KRM-1648,ABI-1648 | DNA/RNA Synthesis |
Rifalazil is a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase. Rifalazil is an antibiotic, exhibits high potency agains... | |||
T79233 | RdRP-IN-6 | DNA/RNA Synthesis | |
RdRP-IN-6 (compound 27) is an inhibitor of RNA-dependent RNA polymerase (RdRp), exhibiting an IC90 value of 14.1 μM. It has potential applications in antiviral and anticancer research [1]. | |||
T83295 | 5-Azacytidine 5′-triphosphate sodium | ||
5-Azacytidine 5'-triphosphate sodium, a cytidine analog, selectively inhibits the incorporation of [3 H]CTP into RNA by DNA-dependent RNA polymerase, without affecting the incorporation of [3 H]UTP [1]. | |||
T83296 | 5-Azacytidine 5′-triphosphate | ||
5-Azacytidine 5′-triphosphate (5-aza-CMP), a cytidine analog, selectively inhibits the incorporation of [^3H]CTP into RNA during the DNA-dependent RNA polymerase reaction, while not affecting the incorporation of [^3H]UT... | |||
T67814 | TMC-649128 PM | ||
TMC-649128 PM is a potent nucleoside inhibitor of the HCV NS5B RNA-dependent RNA polymerase, displaying an EC(50) value of 1.2 muM and showing moderate in vivo bioavailability in rat (F=14%). | |||
T40616 | 8-Azido-ATP | 8-Azidoadenosine 5'-triphosphate,8-N3-ATP,8-Azido-ATP | |
8-Azido-ATP is a nucleotide analog that demonstrates photo-reactivity properties. It offers utility in the precise labeling and identification of proteins, particularly those involved in DNA-dependent RNA polymerase acti... | |||
T35533 | 6-Hydroxypyridin-3-ylboronic Acid | ||
6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block.1,2It has been used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B)... | |||
T35657 | 3'-Deoxyuridine-5'-triphosphate | ||
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T17143 | Toyocamycin | Vengicide | Apoptosis , Others , IRE1 , Antibiotic , Antifungal |
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis. | |||
TN1258 | 3-Acetyl-beta-boswellic acid | 3-O-Acetyl-beta-boswellic acid | DNA/RNA Synthesis |
3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC50 values ranging from 0.6 to 7.1 microM. | |||
T8347 | Rifamycin S | Reactive Oxygen Species , ROS , Antibacterial , Antibiotic | |
Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria | |||
T5003 | Rifamycin sodium | Rifamycin sodium salt | Antibacterial , Antibiotic |
Rifamycin sodium (Rifamycin sodium salt) salt is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase. It is effective against Gram-positive bacteria. | |||
T5075 | Phytic acid potassium | Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt | Others , Endogenous Metabolite |
Phytic acid potassium (Inositol polyphosphate dipotassium salt) exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3 storage depot and precursor for other inositol phosphates and pyrophosphates.... | |||
TN2222 | Sotetsuflavone | Others | |
Sotetsuflavone is a potent inhibitor of DENV-NS5 RdRp (Dengue virus NS5 RNA-dependent RNA polymerase) with an IC50 of 0.16 μM, is the most active compound of this series. | |||
T11233 | Erythromycin thiocyanate | Antibacterial | |
Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nuc... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06071 | SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) | SARS-CoV-2 | Baculovirus-Insect Cells |
TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPH-00681 | SsPB Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase wh... | |||
TMPY-05024 | Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS5 protein (His) | ZIKV | Baculovirus-Insect Cells |
Zika virus NS5 is involved in methytransferase and RNA guanylytransferase activities and capping and synthesis of RNA. And, NS5 is also an RNA-dependent RNA polymerase. | |||
TMPH-02864 | Wnt1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Rna-dependent RNA polymerase part of the packaging complex that packages the viral RNA segments, replicate them into a double-stranded form and transcribe them. | |||
TMPY-05749 | SARS-CoV-2 NSP8 Protein (Avi) | SARS-CoV-2 | E. coli |
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka... | |||
TMPY-06416 | SARS-CoV-2 NSP8 Protein | SARS-CoV-2 | E. coli |
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka... | |||
TMPH-03071 | TAP Protein, Ornithodoros moubata, Recombinant (His & Myc & SUMO) | Ornithodoros moubata | E. coli |
Stimulates translation by blocking the activation of the dsRNA-dependent protein kinase EIF2AK2/PKR, thereby inhibiting the host interferon response. Sigma3 prevents the activation of EIF2AK2 by competing with the kinase... | |||
TMPH-00672 | Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splici... | |||
TMPH-01184 | CYP2A6 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary str... | |||
TMPH-01132 | Complement C8a Protein, Human, Recombinant (His) | Human | E. coli |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.... | |||
TMPH-02140 | CYP21A2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precurs... | |||
TMPH-02145 | MMP-3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA secondary ... | |||
TMPH-02907 | Sialidase-3 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from... | |||
TMPY-05752 | SARS-CoV-2 3CLpro/3C-like protease Protein (His) | SARS-CoV-2 | Baculovirus-Insect Cells |
3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication an... | |||
TMPH-01484 | SMYD3 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory... | |||
TMPH-01247 | POLR3K Protein, Human, Recombinant (His) | Human | Baculovirus |
ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged ... | |||
TMPH-01133 | Complement C8b Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio... | |||
TMPH-01134 | Complement C8g Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio... | |||
TMPY-05727 | SARS-CoV-2 3CLpro/3C-like protease Protein (His & Avi) | SARS-CoV-2 | E. coli |
3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication an... | |||
TMPJ-01428 | SARS-CoV-2 NSP8 Protein (His) | SARS-CoV-2 | E. coli |
Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are... | |||
TMPH-00518 | StxB2 Protein, Enterobacteria phage 933W, Recombinant (His & SUMO) | Enterobacteria phage 933W | E. coli |
One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; With S5 and S12 plays an important role in translational accuracy; ma... | |||
TMPH-02905 | TRPC1 Protein, Mouse, Recombinant (His) | Mouse | in vitro E. coli expression system |
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction w... | |||
TMPH-01920 | P4HA3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR... | |||
TMPH-01958 | Wnt2 Protein, Human, Recombinant (His) | Human | Baculovirus |
RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized withi... | |||
TMPH-02906 | Sialidase-1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction w... | |||
TMPY-02311 | AGO3 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Argonaute (Ago) protein family plays a key role in the RNA interference (RNAi) process in different insects including Lepidopteran. AGO3 also coexists and interacts with Armitage in the mitochondrial fraction. Furthermo... | |||
TMPH-03734 | Zaire ebolavirus (strain Mayinga-76) L Protein (His) | ZEBOV | E. coli |
RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras... | |||
TMPH-03735 | Zaire ebolavirus (strain Kikwit-95) L Protein (His & Myc) | ZEBOV | E. coli |
RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras... | |||
TMPH-02144 | Striatin-3 Protein, Human, Recombinant (His) | Human | E. coli |
RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras... | |||
TMPH-03491 | SARS-CoV-2 Non-structural protein 9/NSP9 Protein (His) | SARS-CoV-2 | E. coli |
The recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 9 (NSP9) is a full-length protein expressed in E.coli. It contains the 1-113 amino acid sequence of human SARS-CoV-2 and... | |||
TMPH-01922 | Promotilin Protein, Human, Recombinant (GST & His & Myc) | Human | E. coli |
Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the b... | |||
TMPH-02152 | Sucrase-isomaltase/SI Protein, Human, Recombinant (His) | Human | Baculovirus |
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host... | |||
TMPH-02151 | OXCT1 Protein, Human, Recombinant (His) | Human | E. coli |
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host... | |||
TMPH-00493 | IL-13 Protein, Canine, Recombinant (His) | Canine | E. coli |
Highly processive DNA-dependent RNA polymerase that catalyzes the transcription of class II and class III viral genes. Recognizes a specific promoter sequence and enters first into an 'abortive phase' where very short tr... | |||
TMPH-02126 | SORBS2 Protein, Human, Recombinant (His) | Human | E. coli |
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host... | |||
TMPH-01131 | Complement C4-B Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs,... | |||
TMPH-00704 | PatZ Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
The authors present evidence that the transcription of the Gcn5-like acetyltransferase YfiQ of Escherichia coli (proposed name: PatZ) is regulated by cAMP-CRP and its implications on acetate metabolism regulation. PMID: ... | |||
TMPH-00120 | Ribonuclease clavin Protein, Aspergillus clavatus, Recombinant (His & Myc) | Aspergillus clavatus | E. coli |
The authors present evidence that the transcription of the Gcn5-like acetyltransferase YfiQ of Escherichia coli (proposed name: PatZ) is regulated by cAMP-CRP and its implications on acetate metabolism regulation. PMID: ... | |||
TMPH-01529 | INMT Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in ... | |||
TMPH-00468 | Interferon-inducible MxA protein Protein, Danio rerio, Recombinant (His) | Danio rerio (Zebrafish) | E. coli |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors a... | |||
TMPY-04775 | CDK1 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
CDC2, also known as CDK1, contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily. CDC2 is a catalytic subunit of the highly conserved prote... | |||
TMPY-04549 | CDK1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
CDC2, also known as CDK1, contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily. CDC2 is a catalytic subunit of the highly conserved prote... | |||
TMPH-01966 | PADI2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active de... | |||
TMPH-02632 | TRIM21 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic c... | |||
TMPJ-01425 | SARS-CoV-2 NSP1 Protein (His) | SARS-CoV-2 | E. coli |
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, po... | |||
TMPY-03288 | USP30 Protein, Human, Recombinant (SUMO) | Human | Baculovirus-Insect Cells |
Ubiquitin specific peptidase 30, also known as USP30, is a deubiquitinating enzyme that is embedded in the mitochondrial outer membrane. Depletion of USP30 expression by RNA interference induced elongated and interconnec... | |||
TMPH-02514 | APOA4 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ... | |||
TMPH-02097 | PPP5C Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitme... | |||
TMPH-00778 | IFN gamma Protein, Guinea Pig, Recombinant (His) | Guinea pig | E. coli |
Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stran... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L6120 | Flavonoid Natural Product Library | 477 compounds | |
A unique collection of 477 flavonoids can be used for high throughput and high content screening; | |||
L1710 | Anti-COVID-19 Compound Library | 1160 compounds | |
A unique collection of 1160 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents; |