T16324 |
Nimbolide
|
|
Apoptosis
,
NF-κB
,
CDK
|
|
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signalin... |
T4672 |
Brevilin A
|
|
STAT
,
JAK
,
Autophagy
,
Apoptosis
,
Anti-infection
|
|
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 si... |
T1849 |
Momelotinib
|
CYT11387,CYT387,LM-1149 |
Apoptosis
,
JAK
,
Autophagy
|
|
Momelotinib is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 n... |
T71639 |
AUH-6-96
|
|
|
|
AUH-6-96 is an inhibitor of JAK/STAT signaling, inhibiting both constitutive and interleukin-6-induced STAT3 phosphoryla... |
T26895 |
BRD0476
|
BRD-0476,BRD 0476,ML 187,ML-187,ML187 |
|
|
BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2... |
T74800 |
HAT-SIL-TG-1&AT
|
|
|
|
HAT-SIL-TG-1&AT is a Janus tyrosine kinase ( JAK ) inhibitor with antitumor effects. HAT-SIL-TG-1&AT is the hypoxia-acti... |
T75535 |
5-epi-Arvestonate A
|
|
|
|
5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense . 5-epi-Arvestonate ... |
T68306 |
INCB16562
|
|
|
|
INCB16562 is a novel, selective, and orally bioavailable small-molecule inhibitor of JAK1 and JAK2 markedly selective ov... |