Search Result

Search Results for " fgfr1 "

Targets

Discoidin Domain Receptor (DDR) FGFR Others

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T11279	FGFR1/DDR2 inhibitor 1		Discoidin Domain Receptor (DDR) , FGFR , Others
	FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.		Discoidin Domain Receptor (DDR) , FGFR , Others
T39992	FGFR1 inhibitor-2	FGFR1 inhibitor-2
	FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer.
T78831	FGFR1 inhibitor-8		FGFR
	FGFR1 inhibitor-8 (Compound 9), an FGFR1 inhibitor with an IC50 of 0.5 nM, binds to the ATP-binding pocket of FGFR1 and exhibits anticancer activity [1].		FGFR
T79686	FGFR1 inhibitor-10		FGFR
	FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation. This compound demonstrates anti-angiogenic and anti-invasion properties, as well as a significant anti-tumor effect [1]...		FGFR
T78830	FGFR1 inhibitor 7		FGFR
	FGFR1 Inhibitor 7 (compound 5), a potent FGFR1 tyrosine kinase inhibitor, exhibits an IC50 of 0.33 nM against its target and demonstrates broad-spectrum cytotoxicity against human cancer cell lines. Additionally, it inhi...		FGFR
T78832	FGFR1 inhibitor-9		FGFR
	FGFR1 inhibitor-9 (Compound 7) is an FGFR1 inhibitor with potent binding affinity, exhibiting an IC50 of 0.85 nM. It targets the ATP-binding pocket of FGFR1 and demonstrates anticancer activity [1].		FGFR
T63816	FGFR1 inhibitor-6
	FGFR1 inhibitor-6 is a potent inhibitor of FGFR1 (IC50: 16.31 nM) with cytotoxic activity. fGFR1 inhibitor-6 is capable of blocking the cell cycle in pro-G1 and G2/M phases and inducing apoptosis.
T78845	FGFR1/VEGFR2-IN-1		VEGFR
	FGFR1/VEGFR2-IN-1 (compound 2b) is an inhibitor of both FGFR1 and VEGFR2, applicable in cancer research [1].		VEGFR
T9030	SU4984		FGFR , IGF-1R , PDGFR
	SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).		FGFR , IGF-1R , PDGFR
T6920	ON123300		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
	ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
T2372	Ponatinib	AP24534	VEGFR , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Autophagy
	Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively).		VEGFR , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Autophagy
T23127	PD-161570	PD 161570	EGFR , FGFR , PDGFR , Src
	PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...		EGFR , FGFR , PDGFR , Src
T6479	Dovitinib lactate hydrate	Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T6082	SSR128129E	SSR	FGFR
	SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.		FGFR
T2642	PD173074		Apoptosis , EGFR , VEGFR , FGFR , IGF-1R , Src
	PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.		Apoptosis , EGFR , VEGFR , FGFR , IGF-1R , Src
T22306	DGY-06-116		FGFR , Src
	DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.		FGFR , Src
TQ0015	PRN1371		c-Fms , FGFR , CSF-1R
	PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).		c-Fms , FGFR , CSF-1R
T37426	FIIN-1	FGFR irreversible inhibitor-1	FGFR
	FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3, FGFR4, Flt1, Flt14, respectively.FIIN-1 inhibited FGFR1, FGFR2,...		FGFR
T3726	Erdafitinib	JNJ-42756493	Apoptosis , FGFR
	Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.		Apoptosis , FGFR
T4318	EOC317	ACTB-1003,ACTB1003,ACTB 1003	VEGFR , FGFR , Tie-2
	EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).		VEGFR , FGFR , Tie-2
T6996	SU 5402	SU5402	VEGFR , FGFR , PDGFR
	SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.		VEGFR , FGFR , PDGFR
TQ0228	Derazantinib	ARQ-087	FGFR
	Derazantinib (ARQ-087) (ARQ-087) is an ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 chondrocytes (IC50s: 4.5 nM/1.8 nM/4.5 nM).		FGFR
T6836	FIIN-2		FGFR
	FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.		FGFR
T5466	Tyrosine kinase-IN-1		VEGFR , FGFR , FLT , PDGFR
	Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）		VEGFR , FGFR , FLT , PDGFR
T1948	AZD4547		VEGFR , FGFR
	AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).		VEGFR , FGFR
T6024	Zoligratinib	FF284,CH5183284,Debio 1347	FGFR
	Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1(IC50=9.3 nM), FGFR2(IC50=7.6 nM), FGFR3(IC50=290), and FGFR4(IC50=22 nM), respectively.		FGFR
T8976	PD-089828		EGFR , FGFR , PDGFR , Src
	PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...		EGFR , FGFR , PDGFR , Src
T12401	Pemigatinib	INCB054828	FGFR
	Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).		FGFR
T16364	Infigratinib phosphate	NVP-BGJ398 phosphate,BGJ-398 phosphate	FGFR
	Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).		FGFR
T15185	Lucitanib	E-3810	VEGFR , FGFR
	Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively).		VEGFR , FGFR
T3492	PD-166866	PD166866	FGFR , Autophagy
	PD-166866 is a selective FGFR tyrosine kinase inhibitor.		FGFR , Autophagy
T1975	Infigratinib	BGJ-398,NVP-BGJ398	Apoptosis , FGFR
	Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.		Apoptosis , FGFR
T5001	Nintedanib esylate	Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120	VEGFR , FGFR , PDGFR
	Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β		VEGFR , FGFR , PDGFR
T5473	ASP5878	ASP-5878	FGFR
	ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.		FGFR
T0520	Lenvatinib	E7080	VEGFR , FGFR , c-RET , PDGFR , c-Kit
	Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (...		VEGFR , FGFR , c-RET , PDGFR , c-Kit
T8541	Lenvatinib mesylate	E7080 (mesylate)	VEGFR , FGFR , c-RET , PDGFR , c-Kit
	Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.		VEGFR , FGFR , c-RET , PDGFR , c-Kit
T3274	S49076		FGFR , c-Met/HGFR , TAM Receptor
	S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.		FGFR , c-Met/HGFR , TAM Receptor
T1777	Nintedanib	BIBF 1120,Intedanib	VEGFR , FGFR , FLT , PDGFR , Src
	Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has an...		VEGFR , FGFR , FLT , PDGFR , Src
T3466	FIIN-3		EGFR , FGFR
	FIIN-3 is an irreversible inhibitor of FGFR.		EGFR , FGFR
T2358	ENMD-2076		Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
	ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T6184	Orantinib	SU6668,TSU-68,NSC 702827	Apoptosis , VEGFR , FGFR , PDGFR
	Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, A...		Apoptosis , VEGFR , FGFR , PDGFR
T61304	FGFR2-IN-1		FGFR
	FGFR2-IN-1 is an FGFR inhibitor that inhibits FGFR1, FGFR2, and FGFR3 with IC50s of 460, 140, and 2200 nM, respectively.FGFR2-IN-1 can be used for the study of cancers associated with FGFR2.CAS 번호13460-73-81-1		FGFR
T4075	Sulfatinib	KDR-IN-1	VEGFR , FGFR , HER
	Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to 24 nM.		VEGFR , FGFR , HER
T6289	Dovitinib	TKI258,CHIR-258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T2372L	Ponatinib Hydrochloride	AP 24534,AP-24534 Hydrochloride,AP-24534,Ponatinib hydrochloride,AP24534 Hydrochloride,AP24534	VEGFR , FGFR , PDGFR , Src
	Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, V...		VEGFR , FGFR , PDGFR , Src
T2361	LY2874455	LY 2874455,LY-2874455	VEGFR , FGFR
	LY2874455 has been used in trials studying the treatment of Advanced Cancer.		VEGFR , FGFR
T6338	PHA-680632	PHA 680632,PHA680632	FGFR , PLK , Aurora Kinase
	PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.		FGFR , PLK , Aurora Kinase
T2341	KW-2449	KW2449	Apoptosis , FGFR , FLT , JAK , Bcr-Abl , Src , c-Kit , Aurora Kinase
	KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 (IC50: 6.6 nM), modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.
TQ0317	R1530	R-1530,R 1530	VEGFR , FGFR , FLT , PDGFR
	R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.		VEGFR , FGFR , FLT , PDGFR
T36680	SM1-71		Serine/threonin kinase , MAPK , LIM Kinase , TGF-beta/Smad , AAK1 (AP2 associated kinase 1)
	SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2.SM1-7...

Compounds

FGFR1/DDR2 inhibitor 1

T11279

Synonym:

Target: Discoidin Domain Receptor (DDR), FGFR, Others

FGFR1 inhibitor-2

T39992

Synonym: FGFR1 inhibitor-2

Target: FGFR, IGF-1R, PDGFR

ON123300

T6920

Synonym:

Target: FGFR, c-RET, JAK, CDK, PDGFR, Src, AMPK

Ponatinib

T2372

Synonym: AP24534

Target: VEGFR, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Autophagy

PD-161570

T23127

Synonym: PD 161570

Target: EGFR, FGFR, PDGFR, Src

Dovitinib lactate hydrate

T6479

Synonym: Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Target: Apoptosis, EGFR, VEGFR, FGFR, IGF-1R, Src

Target: c-Fms, FGFR, CSF-1R

FIIN-1

T37426

Synonym: FGFR irreversible inhibitor-1

Target: FGFR

Erdafitinib

T3726

Synonym: JNJ-42756493

Target: Apoptosis, FGFR

EOC317

T4318

Synonym: ACTB-1003,ACTB1003,ACTB 1003

Target: VEGFR, FGFR, Tie-2

SU 5402

T6996

Synonym: SU5402

Target: VEGFR, FGFR, PDGFR

Target: VEGFR, FGFR, FLT, PDGFR

AZD4547

T1948

Synonym:

Target: VEGFR, FGFR

Zoligratinib

T6024

Synonym: FF284,CH5183284,Debio 1347

Target: EGFR, FGFR, PDGFR, Src

Infigratinib phosphate

T16364

Synonym: NVP-BGJ398 phosphate,BGJ-398 phosphate

Target: VEGFR, FGFR

PD-166866

T3492

Synonym: PD166866

Target: FGFR, Autophagy

Infigratinib

T1975

Synonym: BGJ-398,NVP-BGJ398

Target: Apoptosis, FGFR

Nintedanib esylate

T5001

Synonym: Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120

Target: VEGFR, FGFR, PDGFR

Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit

Lenvatinib mesylate

T8541

Synonym: E7080 (mesylate)

Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit

S49076

T3274

Synonym:

Target: FGFR, c-Met/HGFR, TAM Receptor

Nintedanib

T1777

Synonym: BIBF 1120,Intedanib

Target: VEGFR, FGFR, FLT, PDGFR, Src

Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase

Orantinib

T6184

Synonym: SU6668,TSU-68,NSC 702827

Target: Apoptosis, VEGFR, FGFR, PDGFR

Target: VEGFR, FGFR, HER

Dovitinib

T6289

Synonym: TKI258,CHIR-258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Ponatinib Hydrochloride

T2372L

Synonym: AP 24534,AP-24534 Hydrochloride,AP-24534,Ponatinib hydrochloride,AP24534 Hydrochloride,AP24534

Target: VEGFR, FGFR, PDGFR, Src

LY2874455

T2361

Synonym: LY 2874455,LY-2874455

Target: VEGFR, FGFR

PHA-680632

T6338

Synonym: PHA 680632,PHA680632

Target: FGFR, PLK, Aurora Kinase

KW-2449

T2341

Synonym: KW2449

Target: Apoptosis, FGFR, FLT, JAK, Bcr-Abl, Src, c-Kit, Aurora Kinase

R1530

TQ0317

Synonym: R-1530,R 1530

Target: VEGFR, FGFR, FLT, PDGFR

SM1-71

T36680

Synonym:

Target: Serine/threonin kinase, MAPK, LIM Kinase, TGF-beta/Smad, AAK1 (AP2 associated kinase 1)

Cat No.	Product Name	Synonyms	Targets
T2S0007	Ferulic acid sodium	Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate	FGFR , Reactive Oxygen Species , 5-HT Receptor , Endogenous Metabolite
	Ferulic acid sodium (Sodium ferulic), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.
T2215	Ferulic Acid	Coniferic acid,Fumalic Acid	FGFR , Endogenous Metabolite
	Ferulic Acid (Coniferic acid) is a highly abundant phenolic phytochemical and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong.It can be absorbed by the small intestine and excreted ...		FGFR , Endogenous Metabolite
T40832	Ferulic acid acyl-β-D-glucoside	Ferulic acid glucoside,Ferulic acid acyl-β-D-glucoside
	Ferulic acid acyl-β-D-glucoside, a metabolite of Ferulic Acid, is a novel inhibitor of fibroblast growth factor receptor 1 (FGFR1). It exhibits IC50 values of 3.78 µM and 12.5 µM for FGFR1 and FGFR2, respectively.

Natural Products

Ferulic acid sodium

T2S0007

Synonym: Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate

Target: FGFR, Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite

Ferulic Acid

T2215

Synonym: Coniferic acid,Fumalic Acid

Target: FGFR, Endogenous Metabolite

Ferulic acid acyl-β-D-glucoside

T40832

Synonym: Ferulic acid glucoside,Ferulic acid acyl-β-D-glucoside

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-06036	FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01011	FGFR1 Protein, Human, Recombinant (His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPK-00393	FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen...
TMPY-06034	FGFR1 Protein, Human, Recombinant (beta (IIIb), His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPK-00395	FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen...
TMPK-00392	FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num...
TMPK-00394	FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num...
TMPY-06035	FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05777	FGFR1 Protein, Human, Recombinant (hFc)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-03455	FGFR1OP Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contains 1 LisH domain. A t(6;8)(q27;p11) chromosomal translocati...
TMPY-04371	FGFR1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05761	FGFR1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-03926	FGFR1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-03350	FGFR1 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01781	FGFR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06033	FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01782	FGFR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPH-01337	FGFR1 Protein, Human, Recombinant (Yeast, His)	Human	Yeast
	Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required...
TMPH-01336	FGFR1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required...
TMPY-00756	FGF-1 Protein, Human, Recombinant	Human	E. coli
	aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re...
TMPY-02032	FLRT1 Protein, Human, Recombinant (His)	Human	HEK293
	The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1...
TMPH-00369	FGF-2 Protein, Chicken, Recombinant (His & Myc)	Chicken	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation an...
TMPH-00368	FGF-2 Protein, Chicken, Recombinant (His)	Chicken	Yeast
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation an...
TMPH-03203	FGFb Protein, Rabbit, Recombinant (His & SUMO)	Rabbit	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell di...
TMPY-04025	CEP57 Protein, Human, Recombinant (GST)	Human	E. coli
	CEP57 is a centrosomal protein and is involved in nucleating and stabilizing microtubules. CEP57 was initially identified as a regulator of centriole overduplication in an RNA interference screen. There is a link between...
TMPJ-01224	FGFRL1 Protein, Human, Recombinant (His)	Human	Human Cells
	Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 I...
TMPY-03622	FGF-1 Protein, Canine, Recombinant	Canine	E. coli
	aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re...
TMPJ-00376	IL-17RD Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. IL-17RD functions as a feedback inhibitor o...
TMPY-03477	FGF-1 Protein, Cynomolgus, Recombinant	Cynomolgus	E. coli
	aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re...
TMPY-01089	FGF-1 Protein, Mouse, Rat, Recombinant	Mouse,Rat	E. coli
	aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re...
TMPY-02907	FGF-19 Protein, Human, Recombinant	Human	E. coli
	FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu...
TMPY-03578	FLRT2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Fibronectin Leucine-Rich Transmembrane (FLRT) proteins are glycosylated membrane proteins expressed at the cell surface which localise in a homophilic manner to cell-cell contacts expressing the focal adhesion marker vin...
TMPY-02048	FLRT2 Protein, Human, Recombinant (His)	Human	HEK293
	Fibronectin Leucine-Rich Transmembrane (FLRT) proteins are glycosylated membrane proteins expressed at the cell surface which localise in a homophilic manner to cell-cell contacts expressing the focal adhesion marker vin...
TMPY-02240	STAT1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate t...
TMPY-00338	IL-17RD Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Interleukin-17 receptor D (IL-17D) also known as Interleukin-17 receptor-like protein, is a member of the interleukine-17 receptor family. IL-17RD functions as a feedback inhibitor of fibroblast growth factor-mediated Ra...
TMPY-00625	IL-17RD Protein, Canine, Recombinant (His)	Canine	HEK293
	Interleukin-17 receptor D (IL-17D) also known as Interleukin-17 receptor-like protein, is a member of the interleukine-17 receptor family. IL-17RD functions as a feedback inhibitor of fibroblast growth factor-mediated Ra...
TMPY-00844	IL-17RD Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-17 receptor D (IL-17D) also known as Interleukin-17 receptor-like protein, is a member of the interleukine-17 receptor family. IL-17RD functions as a feedback inhibitor of fibroblast growth factor-mediated Ra...