Cyclo(Pro-Pro)

Cyclo(Pro-Pro) tasted bitter.Verpacamides A-D, a sequence of C11N5 diketopiperazines relating cyclo(Pro-Pro) to cyclo(Pro-Arg), from the marine sponge Axinella vaceleti is possible biogenetic precursors of pyrrole-2-aminoimidazole alkaloids.

Cyclo(L-Pro-L-Ile) is a bis-ketopiperazine from Bacillus thuringiensis that induces a moderate hypersensitivity reaction and can be used to study pine wilt.

Cyclo(L-Pro-L-Val), a 2,5-diketopiperazine extracted from the fruits of Mycobacterium chiliolyticum AZ2 and Mycobacterium leprae, possesses anti-inflammatory activity and virulence activity against phytopathogenic microorganisms (e.g., R. fascians LMG 3605) and inhibits Gram-positive plant pathogens.Cyclo(L-Pro-L-Val) significantly inhibited IKKα phosphorylation and IκBα and NF-κB activation as well as iNOS and COX-2 activation in a concentration Cyclo(L-Pro-L-Val) significantly inhibited the phosphorylation of IKKα, IKKβ, IκBα, and NF-κB, as well as the activation of iNOS and COX-2 in a concentration-dependent manner, and is a potential therapeutic agent for the treatment of inflammation-related diseases.

Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the blood-brain barrier and impact various inflammatory and stress responses [1, 2].

Cyclo(his-pro) is an endogenous cyclic dipeptide that exerts oxidative damage protection by selectively activating the transcription factor Nrf2 signalling pathway.

Cyclo(Pro-Leu) (Cyclo-L-prolyl-L-leucine) is a marine-derived natural product with brine shrimp lethality.

Cyclo(D-Phe-L-Pro) is a natural product from Phellinus igniarius.

Cyclo(L-Ala-L-Pro) and cyclo(L-Val-L-Pro) inhibit aflatoxin production of Aspergillus parasiticus and Aspergillus flavus in liquid medium at concentrations of several hundred uM without affecting fungal growth.

Cyclo(D-Leu-L-Pro) shows antitumour and antifungal activities.

Cyclo(Pro-Ala) is a natural product.

Cyclo(Gly-(L)-Pro) shows immunostimulatory properties. Cyclo(Gly-l-Pro) exhibits potent inhibition of TNF-α release with the IC50 values of 4.5 ug/mL, respectively, it also exhibits significant diminution of IL-1β and IL-6 mRNA-expression levels and NO pr

Cyclo(D-Val-L-Pro) is a natural product for research related to life sciences. The catalog number is TN6670 and the CAS number is 27483-18-7.

Cyclo(L-Leu-trans-4-hydroxy-L-Pro) is a natural product from Phellinus igniarius.

Cyclo(L-Phe-trans-4-hydroxy-L-Pro) (Cyclo(L-phenylalanyl-trans-4-hydroxy-L-proline)) is a natural product found in Phellinus igniarius.

Cyclo(Pro-Gly) is an active metabolite of piracetam-N-phenylacetyl-L-prolylglycine (GWS-111), it shows a greater resistance to an enzymatic effect than natural neuropeptides. Cyclo-(Gly-Pro) shows cytotoxicity at the concentration of 10 umol/L, it inhibit

Cyclo(Pro-Val) (Cyclo(prolylvalyl)) is obtained from the marine fungus and shows moderate antifungal and weak antitumor activities. Cyclo(Pro-Val) inhibits the growth of Bacillus subtilis with MIC of 0.8 g L.

Cyclo(Tyr-Pro) shows antibacterial activity towards several marine bacterial species, it also shows weak antagonistic activity against VEGFR2 -CD. Cyclo(Tyr-Pro) and cyclo(Pro-Val) are toxic to both suspension cells and seedlings of Pinus thunbergii, whic

Cyclo(Pro-Trp) and cyclo(Phe-Pro) show broad spectrum antibacterial properties.

Cyclo(Ser-Pro) is a natural product that can be used as a reference standard. The CAS number of Cyclo(Ser-Pro) is 1355217-25-2.

Cyclo(Phe-Pro) acetate(14705-60-3 free base), known as a secondary metabolite of some bacteria and fungi, is also produced by Vibrio vulnificus.

Maculosin is a secondary metabolite of fungi and bacteria.

Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), is a naturally occurring 2,5-diketopiperazine with notable breast cancer resistance protein inhibitory activity.