β-glucan

Carboxymethyl β-glucan is a derivative of β-glucan with immunostimulatory properties. Carboxymethyl β-glucan can be utilized in the synthesis of nanocarriers.

Whole Glucan Particles act as agonists for Dectin-1a and enhance the innate immune system by improving the functionality of immune cells such as macrophages and monocytes.

Rezafungin (SP-3025) is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.

D75-4590 is a β-1,6-Glucan inhibitor. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, D75-4590 can fight fungal infections by inhibiting its synthetase.

Laminaran is a β-1,3-glucan isolated from brown algae, often serving as a typical ligand for Dectin-1. It possesses anti-cancer, immune-modulating, and radiation-protective properties. Laminaran can be catalyzed by glucanase. In in vitro and in vivo experiments, Laminaran has demonstrated anti-tumor activity and may be used for severe cancers.

Lentinan, isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.

β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis.

β-1,3-Glucan is a major constituent of all characterized fungal cell walls, comprising 30% to 80% of wall mass, and β-1,3-Glucan exists as a branched polymer in the cell wall, with branches connected via β-1,6 linkages, enabling investigation into fungal structural biology, cell wall assembly, immunomodulation, and antifungal therapeutic targeting.

Micafungin sodium (FK 463) is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity.

Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species.

Anidulafungin (Ecalta) (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity.

α-Amylase, Human Saliva (1,4-alpha-D-Glucan-glucanohydrolase, ptyalin), is a biomaterial or organic compound utilized for research in the life sciences.

α-Amylase, Human Pancreas (Amylase, a-Amylase, 1,4-a-D-glucan glucanohydrolase, glycogenase) serves as a biological material or organic compound suitable for life sciences research.

D-Glucan is an orally active immune activator of the Dectin-1 receptor and possesses antioxidant properties (reduces TNF-α). It activates macrophages and neutrophils, eliminates free radicals, inhibits oxidative stress and inflammatory responses, and enhances insulin sensitivity. Additionally, D-Glucan enhances the activity of the antioxidant enzyme glutathione, inhibits gluconeogenesis, and activates GK, promoting glycolysis. It is applicable in research on liver injury protection (antagonizing Acetaminophen toxicity), radiation protection (in synergy with vitamin E), and diabetes (improving glucose metabolism).

TRITC-dextran MW 500000 (Tetramethyl rhodamine isothiocyanate glucan, MW 500000) is a fluorescent dye with a molecular weight of 500 kD. It has an excitation wavelength of 555 nm. This compound is utilized in drug delivery due to the stability of TRITC across a broad pH range (pH 2–11) and its resistance to photobleaching.

TRITC-dextran MW 20000 is a fluorescent dye with a molecular weight of 20 kD and an excitation wavelength of 555 nm. This compound is capable of penetrating the vasculature and can be used to label plasma for visualizing the vascular system. Furthermore, TRITC-dextran MW 20000 is employed in drug delivery due to its stability across a wide pH range (pH 2–11) and its resistance to photobleaching.

TRITC-dextran (MW 70000) is a fluorescently labeled dextran with a molecular weight of approximately 70 kDa and an excitation wavelength of 555 nm, and due to the high photostability of TRITC across a pH range of 2–11 combined with strong resistance to photobleaching, TRITC-dextran (MW 70000) is frequently applied in drug delivery research, vascular permeability studies, and fluorescence-based tracking of macromolecular transport.

TRITC-dextran MW 40000 is a fluorescent dye with a molecular weight of 40 kD. Its excitation wavelength is 555 nm. This compound can penetrate blood vessels and label plasma to visualize the vascular system. It is utilized in drug delivery systems because TRITC maintains stability across a broad pH range (pH 2–11) and exhibits resistance to photobleaching.

TRITC-dextran MW 150000 is a fluorescent dye with a molecular weight of 150 kD. It has an excitation wavelength of 555 nm. This compound is utilized in drug delivery systems due to its stability across a broad pH range (pH 2–11) and resistance to photobleaching.

TRITC-dextran MW 2000000 is a fluorescent dye with a molecular weight of 2000 kD. It possesses an excitation wavelength of 555 nm and is utilized in drug delivery systems. Its stability over a wide pH range (pH 2–11) and resistance to photobleaching make it particularly useful for this application.

TRITC-dextran MW 4000 is a fluorescent dye with a molecular weight of 4 kD and an excitation wavelength of 555 nm. It is known for its vascular permeability and ability to label plasma for imaging the vascular system. This compound is utilized in drug delivery due to its stability across a broad pH range (pH 2–11) and resistance to photobleaching.

Endo-1,3-β-glucanase (Lyticase) is a glucanase from fungi and Chlamydomonas reinhardtii scallops that shows cleavage activity on fungal cells.Endo-1,3-β-glucanase randomly cleaves the β-1-3 glycosidic bond along the β-glucan chain.

1,3-β-Glucanase is a biochemical reagent utilized as a biomaterial or organic compound in life science research.

β-Glucanase 1(thermostable) is a glucosidase located at the brush border of the small intestine, targeting β1→4 glycosidic bonds between glucose or glucose-substituted molecules (such as the disaccharide cellobiose). This enzyme is an exocellulase specific to various β-D-glycosidic substrates. It catalyzes the hydrolysis of non-reducing terminal residues of β-D-glucosides, releasing glucose.