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Enzyme substrate dyes Enzyme substrate dyesProtease substrates
Protease substrate dyes are compounds designed specifically for detecting protease activity. They are usually composed of a peptide segment that can be recognized and cleaved by a specific protease and a chromogenic or fluorophore. When the protease acts on the substrate, a chromogenic or fluorescent signal is released, thereby achieving quantitative analysis of protease activity. This type of dye is widely used in intracellular protease activity research, drug screening, and disease diagnosis.
4-MUNANA
T3812076204-02-9
4-MUNANA is a fluorescent substrate employed in neuraminidase activity assays and serves as a neuraminidase substrate analogue.
- $31
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QTY
Nitro blue tetrazolium chloride
T19032298-83-9
Nitro blue tetrazolium chloride (NBT), an NADPH-diaphorase substrate (IC50 = 3-4 M) and well-known scavenger of superoxide anions, competitively inhibits nitric oxide synthase. Additionally, NBT, as a substrate for dehydrogenases, is used with the alkaline phosphatase substrate BCIP in western blotting and immunohistological staining procedures.
- $42
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QTY
ABTS diammonium salt
T1890830931-67-0
ABTS diammonium salt (AzBTS-(NH4)2) is a substrate of horseradish peroxidase.
- $35
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QTY
Boc-Gln-Ala-Arg-AMC hydrochloride
T74040201849-55-0
Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorescent compound used as a substrate for trypsin and for assessing the protein hydrolysis activity of TMPRSS2.
- $47
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QTY
4-Methylumbelliferyl oleate
T7838618323-58-5
4-Methylumbelliferyl oleate is a fluorescent substrate for lipases (Ex/Em=320/450 nm), which can be cleaved by lipase and can be used to measure pancreatic inhibitory activity.
- $30
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X-Gluc Dicyclohexylamine
T1907618656-96-7
X-Gluc Dicyclohexylamine (5-Bromo-4-chloro-3-indolyl-beta-D-glucuronide cyclohexylammonium salt) is a reagent to detect β-glucuronidase and can be used in molecular biology experiments to mark and select the expression of target genes.
- $30
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BCIP
T189236578-06-9
BCIP (BCIP p-toluidine salt) (BCIP p-toluidine salt) is an artificial chromogenic substrate. It is used for the sensitive colorimetric detection of alkaline phosphatase activity.
- $85
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QTY
Ac-YVAD-AFC
T78431219137-85-6
Ac-YVAD-AFC is a fluorescent peptide substrate used to detect caspase-1. When cleaved, it releases the fluorescent molecule AFC, with an excitation wavelength of 400 nm and an emission wavelength of 505 nm.
- $44
Size
QTY
Z-IETD-AFC
T36333219138-02-0
Z-IETD-AFC is a fluorescent substrate for caspase-8 and granzyme B. It can be used to quantify cysteinyl aspartate-8 or granzyme B activity.
- $60
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MeOSuc-AAPV-AMC
T3836472252-90-5
MeOSuc-AAPV-AMC (MeOSuc-Ala-Ala-Pro-Val-AMC) is a tetrapeptide that is a fluorescent substrate for human leukocyte and porcine pancreatic elastase.
- $40
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QTY
Dansylcadaverine
T1896810121-91-2
Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.
- $29
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QTY
4-Methylumbelliferyl-β-D-glucuronide hydrate
T18887881005-91-0
4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrate (λex=362 nm, λem=445 nm).
- $39
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QTY
IDT307
T385161141-41-9
IDT307 is a fluorescent analog of MPP+, a fluorescent substrate for DAT (fluorescent substrate APP+), and can be used for rapid identification and characterization of PMAT inhibitors.
- $29
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QTY
BCDA
T188803252-36-6
BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate utilized to detect esterase activity.
- $30
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QTY
Msr-Ratio
T398172290635-22-0In house
Msr-Ratio (Msr-green) (Msr-green) is a ratiometric fluorescent probe specifically designed for the detection of methionine sulfoxide reductase (MSR) activity. It has an excitation wavelength of 375 nm and an emission wavelength of 550 nm. This probe offers the ability to monitor the enzyme activity both in vitro and in live cells, making it a valuable tool for studying MSR function.
- $30
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5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside
T60017177966-52-8
5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases.
- $31
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EDANS sodium
TD0082100900-07-0
EDANS sodium (5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt) is a donor for developing FRET-based nucleic acid probes that is widely used in real time PCR assays.
- $37
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Mca-YVADAP-Lys(Dnp)-OH
T76090189696-01-3
Mca-YVADAP-Lys(Dnp)-OH serves as a fluorogenic substrate specifically for caspase-1 and angiotensin-converting enzyme 2 (ACE2) [1].
- $195
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Gly-Gly-AMC
T82281208645-74-3
Gly-Gly-AMC (H-Gly-Gly-AMC) is a fluorogenic substrate for cathepsin C, used for quantifying cathepsin C activity.
- $113
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6-alkyne NAD+ sodium
T83799
6-alkyne NAD+ sodium (6-Parg NAD sodium) is a clickable signaling molecule and enzyme cofactor in NAD+ form. It is used in conjunction with fluorescence labeling for detecting poly(ADP-ribose) polymerase (PARP) protein substrates.
- $1,300
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Boc-Val-Pro-Arg-MCA hydrochloride
T7840970375-24-5
Boc-Val-Pro-Arg-MCA hydrochloride (Boc-Val-Pro-Arg-MCA HCl) is a sensitive fluorescent substrate for the determination of trypsin-like serine proteases activity.
- $91
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Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2
T370251926163-82-7
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation emission maxima of 328 420 nm, respectively.
- $738
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Boc-Leu-Ser-Thr-Arg-AMC
T8586873554-93-5
Boc-Leu-Ser-Thr-Arg-AMC serves as a fluorogenic substrate linked with AMC for proteases [1].
- Inquiry Price
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7-Methyl-6-thioguanosine
T1902555727-10-1
MESG, a chromophoric substrate, can be used to quantitate inorganic phosphate.
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