Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T10065 | 2',3'-cGAMP | 1441190-66-4 | 98% |
|
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3... | ||||
T10065L | 2',3'-cGAMP sodium | 2734858-36-5 | 99.71% |
|
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging... | ||||
T11673 | IRAK4-IN-4 | 1850276-58-2 | 99.13% |
|
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhib... | ||||
T12432 | PF-06928215 | 2378173-15-8 | 98.73% |
|
PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ). | ||||
T9213 | G140 | 2369751-07-3 | 98.16% |
|
G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS). | ||||
T5486 | RU.521 | 2262452-06-0 | 98% |
|
RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS. | ||||
T11344 | G150 | 2369751-30-2 | 97.39% |
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G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase... |