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Serotonin Transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein that transports serotonin from the synaptic cleft back to the presynaptic neuron.
Cat. No. Product name CAS No. Purity Chemical Structure
T24613 PF-00217830 846032-02-8 98%
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
T9540 Phenelzine 51-71-8 98%
Phenelzine is an antidepressant and mania drug, which is a monoamine oxidase inhibitor. Its antidepressant effect is similar to that of niacinamide. It can reduc...
T2395L Vortioxetine hydrobromide 960203-27-4 98%
Vortioxetine (Lu AA21004) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
T60671 MAO-B-IN-9 2416910-88-6 98%
MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence. MAO-B-IN-...
T1580 Desvenlafaxine 93413-62-8 98%
Desvenlafaxine is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) an...
T1279 Vilazodone 163521-12-8 98%
Vilazodone is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vil...
T64317 ZZL-7 99141-91-0 98%
ZZL-7 is a fast-onset antidepressant agent. ZZL-7 disrupts the interaction between the neuronal nitric oxide synthase (nNOS) and serotonin transporter (SERT) in ...
T7941 Imipramine hydrochloride 113-52-0 98%
Imipramine (hydrochloride) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds =...
T7061 Duloxetine 116539-59-4 98%
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
T10758L Centanafadine hydrochloride 923981-14-0 98%
Centanafadine hydrochloride is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83...
T0450 Fluoxetine 54910-89-3 98%
Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
T22453 Venlafaxine 93413-69-5 98%
Venlafaxine, an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disord...
T11078 Deschloroclozapine 1977-07-7 98%
Deschloroclozapine is an effective selective chemical generation actuator. Decloclopine is a dual antagonist of dopamine and serotonin receptors. The Kis of dopa...
T0991 Desipramine hydrochloride 58-28-6 98%
Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), d...
T1483 Citalopram hydrobromide 59729-32-7 98%
Citalopram, a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activ...
T2395 Vortioxetine 508233-74-7 98%
Vortioxetine is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransfera...
T0255 Clomipramine hydrochloride 17321-77-6 98%
Clomipramine hydrochloride is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily abso...
TN2285 DL-Tryptophan 54-12-6 98%
Tryptophan containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its s...
T3526 Dasotraline hydrochloride 675126-08-6 98%
Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50...
T8708 Paroxetine 61869-08-7 98%
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
PF-00217830
T24613
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
Phenelzine
T9540
Phenelzine is an antidepressant and mania drug, which is a monoamine oxidase inhibitor. Its antidepressant effect is similar to that of niacinamide. It can reduc...
Vortioxetine hydrobromide
T2395L
Vortioxetine (Lu AA21004) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
MAO-B-IN-9
T60671
MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence. MAO-B-IN-...
Desvenlafaxine
T1580
Desvenlafaxine is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) an...
Vilazodone
T1279
Vilazodone is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vil...
ZZL-7
T64317
ZZL-7 is a fast-onset antidepressant agent. ZZL-7 disrupts the interaction between the neuronal nitric oxide synthase (nNOS) and serotonin transporter (SERT) in ...
Imipramine hydrochloride
T7941
Imipramine (hydrochloride) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds =...
Duloxetine
T7061
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
Centanafadine hydrochloride
T10758L
Centanafadine hydrochloride is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83...
Fluoxetine
T0450
Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
Venlafaxine
T22453
Venlafaxine, an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disord...
Deschloroclozapine
T11078
Deschloroclozapine is an effective selective chemical generation actuator. Decloclopine is a dual antagonist of dopamine and serotonin receptors. The Kis of dopa...
Desipramine hydrochloride
T0991
Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), d...
Citalopram hydrobromide
T1483
Citalopram, a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activ...
Vortioxetine
T2395
Vortioxetine is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransfera...
Clomipramine hydrochloride
T0255
Clomipramine hydrochloride is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily abso...
DL-Tryptophan
TN2285
Tryptophan containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its s...
Dasotraline hydrochloride
T3526
Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50...
Paroxetine
T8708
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
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