Serotonin Transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein that transports serotonin from the synaptic cleft back to the presynaptic neuron.

Cat. No.	Product name	CAS No.	Purity
T24613	PF-00217830	846032-02-8	98%
T24613	PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizo...
T9540	Phenelzine	51-71-8	98%
T9540	Phenelzine is an antidepressant and mania drug, which is a monoamine oxidase inhibitor. Its antidepressant effect is similar to that of niacinamide. It can reduc...
T2395L	Vortioxetine hydrobromide	960203-27-4	98%
T2395L	Vortioxetine (Lu AA21004) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
T60671	MAO-B-IN-9	2416910-88-6	98%
T60671	MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence. MAO-B-IN-...
T1580	Desvenlafaxine	93413-62-8	98%
T1580	Desvenlafaxine is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) an...
T1279	Vilazodone	163521-12-8	98%
T1279	Vilazodone is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vil...
T64317	ZZL-7	99141-91-0	98%
T64317	ZZL-7 is a fast-onset antidepressant agent. ZZL-7 disrupts the interaction between the neuronal nitric oxide synthase (nNOS) and serotonin transporter (SERT) in ...
T7941	Imipramine hydrochloride	113-52-0	98%
T7941	Imipramine (hydrochloride) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds =...
T7061	Duloxetine	116539-59-4	98%
T7061	Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
T10758L	Centanafadine hydrochloride	923981-14-0	98%
T10758L	Centanafadine hydrochloride is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83...
T0450	Fluoxetine	54910-89-3	98%
T0450	Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
T22453	Venlafaxine	93413-69-5	98%
T22453	Venlafaxine, an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disord...
T11078	Deschloroclozapine	1977-07-7	98%
T11078	Deschloroclozapine is an effective selective chemical generation actuator. Decloclopine is a dual antagonist of dopamine and serotonin receptors. The Kis of dopa...
T0991	Desipramine hydrochloride	58-28-6	98%
T0991	Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), d...
T1483	Citalopram hydrobromide	59729-32-7	98%
T1483	Citalopram, a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activ...
T2395	Vortioxetine	508233-74-7	98%
T2395	Vortioxetine is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransfera...
T0255	Clomipramine hydrochloride	17321-77-6	98%
T0255	Clomipramine hydrochloride is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily abso...
TN2285	DL-Tryptophan	54-12-6	98%
TN2285	Tryptophan containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its s...
T3526	Dasotraline hydrochloride	675126-08-6	98%
T3526	Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50...
T8708	Paroxetine	61869-08-7	98%
T8708	Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.