y 16

Y16 is a G protein-coupled Rho GEFs inhibitor that synergizes with Rhosin/G04 to inhibit LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling. Y16 is also a specific inhibitor of LARG with a Kd of 76 nM.

Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.

P2Y1-IN-16 is a novel antagonist of P2Y1.

C16Y, a short peptide, serves as an inhibitor for the integrins αvβ3 and α5β1. It targets the cell membrane and exerts its antitumor activity by inhibiting angiogenesis.

WAY 163909 is an effective and selective agonist of the 5-HT(2C) receptor (Ki: 10.5±1.1 nM).

WAY 163909 hydrochloride is an effective agonist for the serotonin 5-HT2C receptor, with an EC50 value of 8 nM and a maximal efficacy of 90%. It shows minimal activity at the 5-HT2A receptor. The compound displays its selectivity with a Ki value of 10.5 nM at the 5-HT2C receptor, compared to higher Ki values at 5-HT2A (212 nM), 5-HT7 (343 nM), and 5-HT2B (485 nM) receptors, and it lacks significant activity at various other receptors.

WAY 161503 hydrochloride is a 5-HT2C receptor agonist.

LY 163443 is an dual receptor antagonist of LTD4 and LTE4.

LY 164929 is a highly selective ligand for the lower affinity [3H]D-Ala2-D-Leu-5-enkephalin binding site.

LY-165163 is a selective antagonists of 5-HT1A and 5-HT1D serotonin receptor.

LY 163252 is a bio-active chemical.

LY 164846 is a novel oral cephalosporin that is effective against Staphylococcus, Streptococcus, Haemophilus influenzae, Catabella and Neisseria.

(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor [Ki: 4 nM; EC50: 12 nM], exhibiting anti-obesity and antidepressant effects.

(Z)-3,11-dimethy-7-methylene-9,14-epoxy-1,6,10-dodecatrien-3-ol is a useful organic compound for research related to life sciences and the catalog number is T125942.

15-Hydroxy-16-kauren-19-oic acid is a useful organic compound for research related to life sciences and the catalog number is T131456.

Y16526 is a potent inhibitor of the CBP/p300 bromodomain (CBP/p300bromodomain) with an IC50 of 0.03 μM. Y16524 shows potential for research in acute myeloid leukemia (AML).

Y16524 is a potent inhibitor of the CBP/p300 bromodomain (CBP/p300bromodomain) with an IC50 value of 0.01 μM. It shows potential for research in acute myeloid leukemia (AML).

WAY-166818 (WAY-818) is a synthetic nonsteroidal estrogen that acts as a selective agonist for ERβ.

The compound is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase.

EM 5519 is an antitumor antibiotic.

Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity for the treatment of metastatic melanoma that cannot be resected or has a BRAF V600E or V600K mutation.

AL-3138 is a prostaglandin F2alpha (PGF2alpha) analogue which antagonizes FP prostanoid receptor-mediated inositol phosphates generation.

Safracin A is an antibiotic produced by Pseudomonas fluorescens A2-2.

3-(β-D-Glucopyranosyloxy)-1,6-dihydroxy-2-methyl-9,10-anthracenedione, also known as an anthraquinone, has been specifically extracted from [Rubia cordifolia].