urea

Urea (Carbonyldiamide) is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for about one-half of the total urinary solids.

1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea is a useful organic compound for research related to life sciences. The catalog number is T67700 and the CAS number is 1144075-47-7.

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular carcinoma cell lines[1].

Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker used in PROTAC synthesis.

C16-Urea-Ceramide s a neutral ceramidase (nCDase) inhibitor. It is a bioactive ceramide.

1-Cyclohexyl-3-dodecyl urea (NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor.

Glu-urea-Lys is a molecular scaffold that targets PSMA and can be used as a prostate cancer imaging agent to study prostate-specific membrane antigens.

Glu-urea-Lys TFA (1025796-69-3 free base) is a PSMA inhibitor.

(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) with a Ki of 0.06 nM, useful for research on Parkinson's disease and dementia with Lewy Bodies (DLB) [1].

NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.

Imidazolidinyl urea (Imidurea) is an antimicrobial preservative used in cosmetics.

Diazolidinyl urea (Germall II) is a formaldehyde-releasing preservative used in cosmetics and personal-care products,

Imidazolidinyl urea (Standard) is the standard substance of Imidazolidinyl urea, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Imidazolidinyl urea (Imidurea) is an antimicrobial preservative used in cosmetics.

Urea-15N2 (Standard) is a reference standard of Urea-15N2 intended for quantitative analysis, quality control, and related biochemical research applications. Urea-15N2 is the 15N labeled form of Urea. Urea serves as a potent protein denaturant, operating through both direct and indirect mechanisms. It acts as an effective emollient and keratolytic agent and is used as a diuretic. Blood urea nitrogen (BUN) has been employed to assess kidney function. Additionally, it is widely used as a nitrogen source in fertilizers and is a significant raw material in the chemical industry.

Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.

Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.

N-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea is a potent TRPV1 antagonist, blocking activation of TRPV1 by capsaicin with the IC50 of 123 nM.

TNF-α agonistic 1, a TNF-α agonistic compound, could induce cells to secrete TNF- α.

1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]urea is a chemical compound.

mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.

L-Ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.

PZL-A, an activator of mtDNA synthesis, restored the function and activity of the most common POLγ mutant variant and activated mtDNA synthesis in the cells of pediatric patients with fatal diseases, thereby enhancing the oxidative phosphorylation mechanism and the biogenesis of cellular respiration, and can be used to treat progressive diseases associated with mtDNA depletion.

Fenchyl alcohol is a monoterpene alcohol extracted from the essential oil of Douglas fir leaves and used as a flavor. It significantly inhibits the activity of rumen microorganisms in sheep and deer.

RSV604 ((S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea) is an inhibitor of respiratory syncytial virus (RSV) that binds to RSV nucleoprotein (Kd = 1.31 μM)