20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19161 | 7α-Hydroxycholesterol | Others | |
7α-Hydroxycholesterol is a cholesterol oxide formed by both enzymatic and non-enzymatic oxidation. It can be used as a biomarker for lipid peroxidation. | |||
T8461 | SKI V | Apoptosis , PI3K , S1P Receptor | |
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity | |||
T41324 | L319 | Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate | Others |
L319 (Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate) is a lipid membrane, a potential nucleic acid carrier. | |||
T19080 | DOPE | Others | |
DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery. | |||
T37184 | CX08005 | 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid | Phosphatase |
CX08005 is a protein tyrosine phosphatase 1B inhibitor. CX08005 reduces hepatic lipid accumulation and microcirculatory impairment associated with non-alcoholic fatty liver disease. | |||
T22812 | GRI977143 | GRI 977143 | LPA Receptor |
GRI977143 is a selective and non-lipid agonist of LPA2 (EC50 = 3.3 μM). GRI977143 inhibits the activation of caspases 3, 7, 8, and 9 and and reduces DNA fragmentation. | |||
T14933 | Cetaben | Others | |
Cetaben is a PPARα-independent peroxisome proliferator and is a non-fibrate hypolipidemic drug. It potent reduces the concentration of cholesterol and triglycerides. | |||
T4313 | Tinoridine hydrochloride | Nonflamin,Y-3642 hydrochloride | COX , Glutathione Peroxidase |
Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxid... | |||
T28978 | Tirilazad mesylate | U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate | Antiviral |
Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal c... | |||
T37526 | 2-Oleoylglycerol | 2-Oleoyl Glycerol,2-OG,2-Monoolein | GPR |
2-Oleoylglycerol is a lipid found in palm kernel, sunflower seed and rice bran.2-Oleoylglycerol acts as a GPR119 agonist with neuroprotective effects and induces secretion of glucagon-like peptide 1 (GLP-1).2-Oleoylglyce... | |||
T64297 | Triton X-100 | ||
Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is list... | |||
T14775 | Bragsin2 | 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2 | Others |
Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase acti... | |||
T8902 | DOTMA | Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium | Others |
DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in lipos... | |||
T22070 | DBIBB | LPA Receptor | |
DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of acute radiation syndrome caused by high intensity gamma ra... | |||
T2163 | Dihydrocapsaicin | CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide | Others , TRP/TRPV Channel |
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an... | |||
T25885 | NSC12404 | CID 224134,CID224134,CID-224134,NSC 12404,NSC-12404 | |
NSC-12404 is a selective non-lipid LPA2/3 agonist. | |||
T74445 | ZA3-Ep10 | ||
ZA3-Ep10, a zwitterionic lipid, is utilized in the formulation of lipid nanoparticles for RNA delivery in vivo and non-viral CRISPR/Cas gene editing applications. | |||
T74238 | BGTC | ||
BGTC, a non-amino acid cationic lipid, serves as a vehicle for nucleic acid delivery [1]. | |||
T74313 | MVL5 | ||
MVL5, a non-degradable multivalent cationic lipid, serves as a highly efficient vector for both DNA and siRNA [1]. | |||
T35801 | ML-262 | ||
ML-262 is an inhibitor of hepatic lipid droplet formation (IC50 = 6.4 nM in murine AML-12 cells), which is associated with non-alcoholic fatty liver disease. ML-262 does not induce cytotoxicity (up to 33 μM) or inhibit f... |