nh-3

NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the binding of thyroid hormones to their respective receptors, resulting in hindered cofactor recruitment.

3'-NH-Tr-2',3'-ddC(Bz)-5'-CE-Phosphoramidite is a phosphoramidite monomer utilized in the synthesis of nucleic acids, including oligonucleotides.

3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.

3'-NH-Tr-2',3'-dT-5'-CE-Phosphoramidite is a specialized phosphoramidite compound used in the synthesis of oligonucleotides and nucleic acid analogs. It plays a role in research focused on antiviral and anticancer applications.

3'-NH-Tr-2',3'-ddG(iBu)-5'-CE-Phosphoramidite is a nucleoside phosphoramidite monomer featuring protective group modifications, suitable for RNA oligonucleotide synthesis.

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

3-Methoxyaniline is an organic compound with the molecular formula CH3OC6H4NH2，3-Methoxyaniline is one of three possible structural isomers of the methoxy-containing aniline derivative.

Boc-NH-PEG3-CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis [1].

Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras).

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative featuring a hydroxyl group and a Boc-protected amino group, used as a PROTAC linker.

Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate.

Aminooxy-PEG3-C2-NH-Boc is a PEGylated PROTAC linker used in synthesizing PROTACs, a new class of bifunctional molecules for targeted protein degradation [1].

APN-C3-NH-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG3-Mal (Biotin-PEG3-NH-Mal) is a biotin-labeled PROTAC linker belonging to the PEG class that can be used to synthesize PROTAC molecules.

Boc-NH-PEG3-propargyl is a PEG-based linker used in PROTACs for connecting two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-sulfonic acid, a polyethylene glycol (PEG) derived linker, is utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Bromoacetamido-PEG3-NH-Boc is a polyethylene glycol (PEG)-based linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Cbz-NH-PEG3-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands crucial for PROTAC molecule formation. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

endo-BCN-PEG3-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands integral to PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Fluorescein-PEG3-NH-Boc is a polyethylene glycol (PEG)-based proteolysis-targeting chimera (PROTAC) linker used for PROTAC synthesis[1].

Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

N-(Azido-PEG3)-NH-PEG3-acid is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

NH-bis(PEG3-azide) is a PROTAC linker of the PEG class used in the synthesis of PROTAC molecules.

NH-bis(PEG3-Boc) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.