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(6)
By Target- RIP kinase
- Necroptosis(2)
- Apoptosis(1)
- Autophagy(1)
- Caspase(1)
- Ferroptosis(1)
- Indoleamine 2,3-Dioxygenase (IDO)(1)
- Others(4)
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Results for "
necrostatin
" in TargetMol Product Catalog- Inhibitors & Agonists12
Necrostatin-1
Necrostatin 1, Nec-1
T18474311-88-0
Necrostatin-1 (Nec-1) is a specific RIP1 inhibitor and necrotic apoptosis inhibitor, which inhibits TNF-α-induced necrotic apoptosis and also inhibits IDO.
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Necrostatin-7
Necrostatin 7, Necrostatin7, Nec 7, Nec-7, Nec7
T25859351062-08-3
Necrostatin-7 (Necrostatin 7) is an inhibitor of necrotic apoptosis with cardioprotective effects, inhibits RANK-NFATc1 signaling, and attenuates macrophage differentiation into osteoblasts.
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Necrostatin-5
Nec-5
T37558337349-54-9
Necrostatin-5 (Nec-5) is a selective RIP1 kinase inhibitor and cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α, with an EC50 of 240 nM.
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Necrostatin 2 racemate
Necrostatin-2 racemate
T7504852391-15-2
Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.
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Necrostatin 2 S enantiomer
T12203852391-20-9
Necrostatin 2 (S enantiomer) is the S enantiomer of Necrostatin 2.
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Necrostatin 2
Necrostatin2
T12203L852391-19-6
Necrostatin 2 is a necrotic protein and receptor-interacting protein kinase 1 (RIPK1) inhibitor used to study inner ear disorders such as sudden deafness, dizziness and tinnitus.
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Cl-Necrostatin-1
T68520862377-51-3
Cl-Necrostatin-1 is an inhibitor of receptor-interacting protein kinase. It inhibits RIPK1 activity.
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Necrostatin-1 (inactive control)
Nec-1 (inactive control)
T8472764419-92-7
Necrostatin-1 (Nec-1) (inactive control), an inactive analog of Necrostatin-1, functions as a potent inhibitor of necroptosis [1].
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Necrostatin-34
2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4
T9095375835-43-1
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
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Necroptosis-IN-1
T93051391980-92-9In house
Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.
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CIL62 
T8468117593-36-9
CIL62 is a Necrostatin-1 dependent inducer of cell death through a caspase-3 7-independent mechanism [1].
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nec-3a
T735211504558-72-8
Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM. This compound successfully impedes the autophosphorylation activity within the RIP1 kinase domain.
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