luteolin

Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities including antitumor, antioxidant, anti-inflammatory, antimicrobial, antiviral, antiallergic, and procoagulant.

Luteolin-7-rutinoside exhibits both antifungal and anti-arthritic activities, potentially serving as a combination therapy for fungal arthritis caused by C. albicans infection.

8-C-(2-Rhamnosyl-6-deoxyhexopyranosulyl)luteolin is a useful organic compound for research related to life sciences. The catalog number is T123914 and the CAS number is 933463-03-7.

Luteolin 5-rutinoside is a useful organic compound for research related to life sciences. The catalog number is T125918 and the CAS number is 140380-87-6.

Luteolin 7-diglucuronide, the major flavonoid isolated from Verbena officinalis and Aloysia triphylla.

Luteolin 7-sulfate, derived from the marine plant Phyllospadix iwatensis Makino, suppresses TYR gene expression by intervening in a signaling pathway involving the cAMP-responsive element binding protein (CREB) and microphthalmia-associated transcription factor (MITF). This inhibition ultimately leads to a decrease in melanin synthesis.

Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) possesses antioxidant activities.

Luteolin-7-O-β-D-glucopyranoside is a chemical compound present in the aerial parts of [Codonopsis nervosa].

Luteolin-7-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside, a flavonoid, exhibits antiradical activity [1].

Luteolin-3',7-di-O-glucoside has anti-ulcer and antioxidant activities.

Luteolin-4'-O-glucoside (Luteolin-4-o-glucoside) is an inhibitor of IL-5 (IC50 = 3.7 μM) with anti-complementary, antioxidant and anticancer activity.

Luteolin 5-O-glucoside, a natural flavonoid, inhibit LPS-induced NO production and t-BHP-induced ROS production in wild-type 264.7 cells, and iNOS and COX-2 expression in macrophages.

Luteolin 7,3'-di-O-glucuronide is a natural product for research related to life sciences. The catalog number is TN4464 and the CAS number is 53965-08-5.

Luteolin 5-methyl ether is a natural product for research related to life sciences. The catalog number is TN5506 and the CAS number is 58115-29-0.

Luteolin 5,3'-dimethyl ether is a natural product for research related to life sciences. The catalog number is TN5508 and the CAS number is 62346-14-9.

Luteolin 7-(6 -β-D-apiofuranosyl-β-D-glucopyranoside) (compound 3), a flavonoid with antioxidant properties, is extracted from Margaritopsis carrascoana. This compound exhibits strong DPPH free radical scavenging activity, demonstrating an IC50 value of 0.188 mg mL.

Luteolin-3-O-beta-D-glucuronide effectively inhibits nitrite production in macrophages.

Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.

8-C-Galactosylluteolin is a useful organic compound for research related to life sciences. The catalog number is T124540 and the CAS number is 61950-88-7.

7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) exhibits anti-inflammatory, antibacterial, and antifungal activities, along with moderate antitrypanosomal activity, having an MIC value of 19.0 µg/mL.

6-Hydroxyluteolin 7-glucoside is derived from Tanacetum parthenium and T. vulgare showing anti-inflammatory effects.

5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. 5,7-Dimethoxyluteolin is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM.

Diosmetin (Luteolin 4-methyl ether) has been found to act as a weak TrkB receptor agonist.

1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive deficits and oxidative stress in AD mice; can exert antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity.