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Cat No. | Product Name | Synonyms | Targets |
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TP1016L | Aviptadil Acetate | Vasoactive Intestinal Peptide acetate salt | RAAS , SARS-CoV |
Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmona... | |||
T80866 | VIP(Guinea pig) TFA | Vasoactive Intestinal Peptide, guinea pig TFA | |
Vasoactive Intestinal Peptide (VIP) Guinea pig TFA, a trophic and mitogenic factor, promotes growth in cultured whole embryos and acts as a gastrointestinal hormone, while also indicating potential neurotransmitter funct... | |||
TP1016 | Aviptadil | Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine) | |
Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction. | |||
T0116 | Balofloxacin | DNA gyrase , Antibacterial , Antibiotic | |
Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase. | |||
T0396 | Pipemidic acid | Acido pipemidico | Antibacterial , Antibiotic |
Pipemidic acid (Acido pipemidico), a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa. | |||
T2451 | GlyH-101 | GlyH 101 | CFTR , Autophagy |
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM. | |||
T1677 | Montelukast | Singular | Leukotriene Receptor , Lipoxygenase , LTR |
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury... | |||
T4503 | Talniflumate | Somalgen | Chloride channel , COX , N-Acetylglucosaminyltransferase , Anion Exchanger |
Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition o... | |||
T20082 | Dymanthine | Adogen 342D,ADMA 18 | Others |
Dymanthine (ADMA 18) is an agent of veterinary anthelmintic. | |||
TP1263 | Fz7-21 | (Ac)-LPSDDLEFWCHVMY-NH2 | Wnt/beta-catenin |
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with e... | |||
T1677L | Montelukast sodium | MK0476 | Leukotriene Receptor , LTR |
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver i... | |||
T2542 | Prucalopride | R-93877 | 5-HT Receptor |
Prucalopride (R-93877) is a selective, high-affinity 5-HT4A/4B receptor agonist (Ki: 2.5/8 nM). It has >290-fold selectivity for 5-HT4A/4B receptor than other 5-HT receptor subtypes. | |||
T2686 | Esomeprazole Magnesium | (S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium | ATPase , Proton pump |
Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block... | |||
T2319 | Acotiamide monohydrochloride trihydrate | Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl | AChE |
Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamid... | |||
T8386 | Esomeprazole Magnesium trihydrate | (S)-Omeprazole magnesium trihydrate | Proton pump |
Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit... | |||
T7587 | Tenapanor | RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722 | Sodium Channel |
Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinica... | |||
T25719 | Lidamidine | Lidamidina,Lidamidinum | Others |
Lidamidine (Lidamidinum) is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle contraction. | |||
T21252 | DHMB | 2,3-Dihydroxy-4-Methoxybenzaldehyde | Others |
DHMB (2,3-Dihydroxy-4-Methoxybenzaldehyde) exerts protective effects on intestinal epithelial cells. DHMB exhibits anti-inflammatory and antifungal capacity. | |||
T14490 | Talipexole dihydrochloride | Domnin,B-HT 920 dihydrochloride | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, ... | |||
T35372 | Zinc acetate | Dicarbomethoxyzinc | Others |
Zinc acetate (Dicarbomethoxy) can induce the expression of metallothionein in intestinal cells. | |||
T5943 | 4,4'-DIMETHOXYBENZIL | p-Anisil | Others |
4,4'-Dimethoxybenzil (p-Anisil) is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM). | |||
T7405 | Piperidolate | AChR | |
Piperidolate inhibits intestinal cramp induced by acetylcholine | |||
T60254 | Calcium glycerophosphate | Phosphorylase | |
Calcium glycerophosphate(CaGP) is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate can be a source of calcium and phosphorus in total parenteral nutrition solutions [1] [2]. | |||
T35337L | Teduglutide acetate | Glucagon Receptor | |
Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy. Teduglutide acetate partially restores small intestinal epithelial function through an altered distribution of claudin-10, facilitati... | |||
T15005 | CP-66948 | Histamine Receptor | |
CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa. | |||
T9549 | Chiniofon | Loretin,Ferron,8-hydroxy-7-iodo-5-quinolinesulfonate,quiniophen | Others |
Chiniofon (Ferron), a halogenated 8-hydroxyquinoline, is used as an antiamebic drug. This type of anti-amebic drug exerts an anti-amebic effect by inhibiting intestinal commensal bacteria and affects amoebic dysentery, b... | |||
T7603 | Pinaverium bromide | Calcium Channel | |
Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain, diarrhea and intestinal discomfort. | |||
TP1376 | GLP-1(7-37) acetate(106612-94-6 free base) | GLP-1(7-37) acetate | Others , Glucagon Receptor |
Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion. | |||
TP1627L | Prepro VIP (111-122), human acetate | Prepro VIP (111-122), human acetate(123025-94-5 free base) | Others |
Prepro VIP (111-122), human acetate is a prepro-vasoactive intestinal polypeptide (VIP)–derived peptide, corresponding to residues 111-122. | |||
T7555 | Piperidolate hydrochloride | AChR | |
Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs). | |||
TP2103L | [D-p-Cl-Phe6,Leu17]-VIP acetate | Others | |
[D-p-Cl-Phe6,Leu17]-VIP acetate is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor (IC50 = 125.8 nM). | |||
T0686 | Orlistat | Ro-18-0647,Tetrahydrolipstatin | Apoptosis , Others , Fatty Acid Synthase |
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor. | |||
T15006 | Dirlotapide | CP742033,Slentrol | Others , CETP |
Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner, possibly by ... | |||
T0170 | Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI) | phosphonomycin calcium,Fosfomycin calcium,phosphomycin calcium | Antibiotic |
Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (9CI) (phosphonomycin calcium) is an antibiotic, used for the treatment of urinary tract infections and intestinal infections caused by susceptible strains. | |||
TP1283L | VIP(6-28)(human, rat, porcine, bovine) acetate | Others | |
VIP(6-28)(human, rat, porcine, bovine) acetate is an antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) receptor on cAMP in the superior cervical ganglion (SCG). | |||
T11063 | DMT1 blocker 1 | Others | |
DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo. | |||
T38253 | Lauroyl-L-carnitine (chloride) | Lauroyl-L-carnitine Hydrochloride | |
Lauroyl-L-carnitine (chloride) (Lauroyl-L-carnitine Hydrochloride), an acylcarnitine and surfactant, has been used to permeate porcine intestinal cells to deliver the polar fluorescent probe fluorescent yellow. | |||
T11064 | DMT1 blocker 2 | Others | |
DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo. | |||
T72054 | SLC26A3-IN-1 | transporter | |
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities ... | |||
T22070 | DBIBB | LPA Receptor | |
DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of acute radiation syndrome caused by high intensity gamma ra... | |||
T3984 | GLP-1(7-36), amide | MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide | Glucagon Receptor |
GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-... | |||
T4272 | 4-Hydroxyquinoline | 4-Quinolinol,Quinolin-4-Ol | Antibacterial |
4-Hydroxyquinoline (4-Quinolinol) is a hydroxylated quinoline derivative with antimicrobial activity. It shows growth-inhibitory effects against intestinal bacteria. It also can be used as sacrificial scavengers of the p... | |||
T1291 | Cisapride | Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase | Potassium Channel , 5-HT Receptor , HER |
Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease... | |||
T70084 | Dersalazine | Dersalazine Free Base | IL Receptor , Platelet aggregation |
Dersalazine (Dersalazine Free Base), an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential effic... | |||
T8526 | Metformin | 1,1-Dimethylbiguanide | Mitophagy , AMPK , Autophagy |
Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is comm... | |||
T1266 | Terfenadine | (±)-Terfenadine,MDL-991 | Apoptosis , Potassium Channel , 5-HT Receptor , Caspase , Na+/Ca2+ Exchanger , HER , AChR , Histamine Receptor |
Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects. | |||
T0066 | Dichlorophen | DDM,Dichlorophene | Antibacterial , Parasite , Antifungal |
Dichlorophen (DDM) is a nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ingredient in antimicrobial soaps and sh... | |||
T13647 | Dextran sulfate sodium salt (MW 4500-5500) | DSS,Dextran sulfate sodium salt (MW 4500-5500) | Apoptosis , HIV Protease |
Dextran sulfate sodium salt (MW 4500-5500) is an anhydrous glucose polymer with a molecular weight range of 4500-5500. Dextran sulfate sodium salt (MW 4500-5500) inhibits human immunodeficiency virus replication by preve... | |||
T5095 | Oxazolone | 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one | Others |
Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory... | |||
T8926 | Salcaprozate sodium | SNAC | Others |
Salcaprozate sodium (SNAC), an oral absorption promoter, serves as a potent delivery agent for oral heparin and insulin by enhancing passive transcellular permeation through small intestinal epithelia. This is achieved t... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8091 | Trans-4-Hydroxycyclohexanecarboxylic Acid | Others | |
trans-4-Hydroxycyclohexanecarboxylic Acid is an organic intermediate. | |||
TN4761 | Phellamurin | P-gp | |
Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred between Phellamurin with cyclosporin, to ensure the efficacy of cyclosporin, we suggest that the coadmini... | |||
T0700 | Ursodeoxycholic acid | UDCA,Ursodiol | Potassium Channel , Endogenous Metabolite |
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption. | |||
T29078 | Ursodeoxycholic acid sodium | UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium | FXR , Endogenous Metabolite , GPCR19 |
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it... | |||
T5066 | Nε,Nε,Nε-Trimethyllysine chloride | Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride | Others , Endogenous Metabolite |
Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor of carnitine and a coenzyme of fatty acid oxidation. Nε,Nε,... | |||
T5281 | Skatole | Scatole,3-Methylindole,3-Methylindole,3-Methyl-1H-indole,beta-Methylindole | AhR , p38 MAPK , Aryl Hydrocarbon Receptor , Endogenous Metabolite , Antibacterial , Autophagy , Antifungal |
Skatole (3-Methyl-1H-indole) is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38. | |||
TN7042 | N-methyltyramine | Adrenergic Receptor | |
N-methyltyramine is an alkaloid isolated from the leguminous plant Acacia grandiflora.It is an α2-adrenoceptor antagonist that regulates adrenergic receptors through enzymatic adrenergic synthesis.It is used in the study... | |||
T5731 | 1-Kestose | Others , Endogenous Metabolite , Antibacterial | |
1-Kestose shows significant anti-hydroxyl radical potential. 1-Kestose can promote intestinal Lactobacillus number, and influence the microorganisms as well as the intestinal and systemic immune responses. | |||
T13752 | L-(+)-Arabinose | Endogenous Metabolite | |
L-(+)-Arabinose selectively inhibits intestinal sucrase activity in a non-competitive manner, inhibiting glucose elevation caused by sucrose intake. | |||
TCS1188 | Mogroside III | Others | |
Mogroside III is a triterpenoid glycoside and a nonsugar sweetener. Mogroside III is transformed by human intestinal bacteria to release secondary glycoside mogroside IIA1 and aglycone mogrol. | |||
T6S0084 | Tuberostemonine | Tuberstemonine | Parasite |
1. Tuberostemonine (Tuberstemonine) exhibits relatively higher intestinal permeabilities. 2. Tuberostemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction. | |||
T10117 | 3'-O-Acetylhamaudol | Others | |
3'- O- Acetylhamaudol, isolated from the roots of Angelica japonica, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation. | |||
T16542 | Piromidic acid | Antibacterial , Antibiotic | |
Piromidic acid is an antibacterial agent. Piromidic acid is active against gramnegative bacteria and staphylococci. It is used for urinary tract and intestinal infections. | |||
TQ0193 | N2,N2-Dimethylguanosine | Endogenous Metabolite | |
N2,N2-Dimethylguanosine is an urinary nucleoside. The mean levels of urinary N2,N2-Dimethylguanosine in patients with colorectal cancer are significantly higher than those in patients with intestinal villous adenoma or h... | |||
TN1714 | Grosvenorine | Grosvenorin | Antibacterial |
Grosvenorine (Grosvenorin) exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of ... | |||
T2840 | Phloracetophenone | 2,4,6-trihydroxyacetophenone,1-(2,4,6-Trihydroxyphenyl)ethanone | Others , P450 , Antibacterial , Antibiotic |
Phloracetophenone (1-(2,4,6-Trihydroxyphenyl)ethanone) has antiobesity and hypolipidemic effects, may be partly mediated by delaying the intestinal absorption of dietary fat by inhibiting pancreatic lipase activity. | |||
T5240 | Cholestenone | (+)-4-Cholesten-3-one | Others , Endogenous Metabolite |
Cholestenone ((+)-4-Cholesten-3-one) is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals. | |||
T5S0056 | Coptisine chloride | Q-100696,NSC-119754 | Indoleamine 2,3-Dioxygenase (IDO) , Influenza Virus , Antibacterial |
1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds. | |||
TN6752 | Dimethyl sulfone | Endogenous Metabolite | |
Dimethyl sulfone exists in all living organisms, ranging from bacteria to humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Dimethyl sulfone ... | |||
T5086 | Pharmatose DCL 14 | D-Lactose monohydrate | Others , Endogenous Metabolite |
Pharmatose DCL 14 (D-Lactose monohydrate) is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Pharmatose DCL 14 is also an important osmotic regulator ... | |||
TMA2440 | Uridine 5'-monophosphate disodium salt | Disodium UMP,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate | Others |
Uridine 5'-monophosphate disodium salt (Disodium UMP) has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucle... | |||
TN6791 | Palvanil | Hexadecanamide | TRP/TRPV Channel |
Palvanil (Hexadecanamide) is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and reduces visceral pain. | |||
T4927 | 4-Guanidinobutanoic acid | 4-GBA,4-Guanidinobutyric acid | Endogenous Metabolite |
4-Guanidinobutanoic acid (4-GBA) is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid transporters hPAT1. | |||
T2965 | Deoxycholic acid | Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic | Endogenous Metabolite , GPCR19 |
Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorptio... | |||
T3S2072 | 3-Butylidenephthalide | Butylidene phthalide,n-Butylidenephthalide | Parasite , Glucosidase |
1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitiv... | |||
T67710 | 3-Indoleacrylic acid | Endogenous Metabolite | |
3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by im... | |||
T6316 | Calcitriol | Topitriol,Rocaltrol,Calcijex,RO215535,1,25-Dihydroxyvitamin D3 | Endogenous Metabolite |
Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorption of calcium and phosphorus, and increases bone resorption... | |||
TN1370 | Allura Red AC | Allura Red,CI 16035,FD&C RED NO. 40 | Others , Estrogen/progestogen Receptor , Androgen Receptor |
Allura Red AC (CI 16035) is a very important food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries.Allura Red AC promotes susceptibility to experimental colitis via mouse intestinal seroto... | |||
T8733 | Antrodin A | camphorataanhydride A | Others |
Antrodin A (camphorataanhydride A) (AdA) is one of the main active ingredients in the solid-state fermented A. camphorata mycelium. It protects the liver from alcohol damage by improving the antioxidant and anti-inflamma... | |||
T0771 | Casanthranol | Others | |
Casanthranol is a concentrated mixture of anthranol glycosides derived from the dried bark of Rhamnus p., commonly known as cascara sagrada. This compound serves as a stimulant laxative that is primarily administered to ... | |||
TN6393 | Fulvotomentoside A | Others | |
Fulvotomentoside A could decrease overexpression of IL-6 and IL-17A, and increase the expression of specific transcription factor Foxp3 of regulatory T cells significantly in intestine. It may be one of the mechanisms th... | |||
T13506 | 3β-Ursodeoxycholic acid | Isoursodeoxycholic acid | |
3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid (administered orally has shown good tolerability and good intestinal absorption. 3β-Ursodeoxycholic acid can undergo enzymatic iso... | |||
T3S1955 | 7-Ethylcamptothecin | Others | |
1. 7-Ethylcamptothecin has the superior antitumor activity than CPT. (a). 7-Ethylcamptothecin has a stronger growth-inhibiting activity against tumor cells. (b). 7-Ethylcamptothecin remains in the intestinal tract for a ... | |||
T1157 | Moxidectin | milbemycin B,CL301423 | GluCls , Antibiotic , Parasite |
Moxidectin (CL301423) is an anthelmintic drug which kills parasitic worms, and is used for the prevention and control of heartworm and intestinal worms. It can be found in treatments prescribed for animals such as dogs, ... | |||
T0847 | Chenodeoxycholic acid | CDCA,Chenodiol | Potassium Channel , FXR , Endogenous Metabolite , Autophagy |
Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as ... | |||
T4S0797 | Berberine | Berberin,Umbellatine | Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy |
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3.... | |||
T3051 | Theaflavin-3-gallate | Theaflavine-3-Gallate | Others |
Theaflavin-3-gallate (Theaflavine-3-Gallate) can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation. Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell... | |||
T2O2777 | L-Threonine | threonine | Others , Endogenous Metabolite |
L-Threonine (threonine) is an essential amino acid in humans,an important amino acid for the nervous system,L-Threonine also plays an important role in porphyrin and fat metabolism and prevents fat buildup in the liver. ... | |||
T5S2360 | Corydaline | Corydalin,(+)-Corydaline | P450 , Virus Protease , Opioid Receptor , AChE |
1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr... | |||
T41245 | Trimethylamine N-oxide | Reactive Oxygen Species , NOD-like Receptor (NLR) , TGF-beta/Smad | |
Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline, betaine, and carnitine via intestinal microbial metabolism that accumulates in tissues of marine animals and prevents the protein-damaging e... | |||
T6S0033 | Crotonoside | Isoguanosine,2-HYDROXYADENOSINE | Others , FLT , HDAC |
1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig and hamster and in stim... | |||
T5S1177 | Aloin B | Isobarbaloin | Others |
Aloin B (Isobarbaloin) is an isomer of aloin.1. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation, the result opens new ... | |||
T1040 | Vitamin B12 | Cyanocobalamin,Cobalamin | Endogenous Metabolite |
Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intes... | |||
T6S0653 | Linarin | Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine | TNF , AChE |
1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat... | |||
T4000 | (±)-Equol | Equol,(R,S)-Equol | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Drug Metabolite |
(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occu... | |||
T1437 | D-Panthenol | D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol | Endogenous Metabolite |
D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis... | |||
T3123 | Allicin | ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection | |
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus... | |||
T6491 | (-)-(S)-Equol | (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite |
(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a... | |||
T36585 | Isodeoxycholic Acid | isoDCA | Chloride channel , Antibacterial |
Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less... | |||
T4938 | Potassium 1H-indol-3-yl sulfate | Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate | AhR , Endogenous Metabolite |
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of imm... | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-02650 | Alkaline phosphatase Protein, Human, Recombinant (His) | Human | HEK293 |
ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activit... | |||
TMPY-02713 | Alkaline phosphatase Protein, Human, Recombinant (hFc) | Human | HEK293 |
ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activit... | |||
TMPY-03597 | VIP Protein, Human, Recombinant (His) | Human | HEK293 |
VIP, or vasoactive intestinal peptide, is a neuropeptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, and it exerts its actions through three G-protein-coupled receptors (PAC1, VPAC1, and VP... | |||
TMPK-00684 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-04828 | TFF3 Protein, Human, Recombinant (His) | Human | HEK293 |
Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types ... | |||
TMPK-00796 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPJ-01173 | TFF3 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process calle... | |||
TMPJ-01423 | GPC3 Protein, Rhesus macaque, Recombinant (His) | Rhesus Macaque | Human Cells |
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate proteoglycan, which is overexpressed in various neoplasms ... | |||
TMPJ-00529 | FABP6 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine ... | |||
TMPJ-00337 | GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate proteoglycan, which is overexpressed in various neoplasms ... | |||
TMPJ-00583 | CDH17 Protein, Human, Recombinant (His) | Human | Human Cells |
Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks ... | |||
TMPJ-00911 | GUCY2C Protein, Human, Recombinant (hFc) | Human | Human Cells |
GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family. GUCY2C cell surface expression is confined to luminal surfaces of the i... | |||
TMPJ-00910 | GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family. GUCY2C cell surface expression is confined to luminal surfaces of the i... | |||
TMPY-01120 | VPAC2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
VIP and PACAP receptor 2, or VIPR2 encodes the VPAC2 receptor, which binds both VIP and PACAP. VPAC2 is expressed throughout the central nervous system and the periphery. Mutations in the VIPR2 homolog in the mouse cause... | |||
TMPH-00399 | RPS13 Protein, Ciona intestinalis, Recombinant (His & Myc) | Ciona intestinalis | E. coli |
TMPY-02919 | Cadherin 17/CDH17 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r... | |||
TMPY-01912 | Cadherin 17/CDH17 Protein, Human, Recombinant (His) | Human | HEK293 |
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r... | |||
TMPY-05352 | Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r... | |||
TMPY-03383 | IL-7 Protein, Human, Recombinant | Human | E. coli |
IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progeni... | |||
TMPY-00524 | IL-7 Protein, Mouse, Recombinant | Mouse | E. coli |
IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progeni... | |||
TMPY-02292 | IGSF11 Protein, Human, Recombinant (His) | Human | HEK293 |
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins sh... | |||
TMPY-01147 | R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) | Human | HEK293 |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-03197 | R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His) | Mouse | CHO |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-03626 | R-Spondin 1/RSPO1 Protein, Human, Recombinant | Human | CHO |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-00665 | Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) | Human | HEK293 |
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam... | |||
TMPY-02938 | REG4 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be inv... | |||
TMPY-02846 | CLPS Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural... | |||
TMPY-01386 | CD155/PVR Protein, Human, Recombinant (His) | Human | HEK293 |
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall... | |||
TMPY-01612 | CD155/PVR Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall... | |||
TMPY-00663 | Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) | Human | HEK293 |
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal... | |||
TMPY-01342 | CD73 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-03540 | CD73 Protein, Rat, Recombinant (His) | Rat | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-00699 | CD155/PVR Protein, Human, Recombinant (hFc) | Human | HEK293 |
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall... | |||
TMPY-01851 | CD73 Protein, Human, Recombinant (His) | Human | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-03377 | CD73 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-02836 | MFGE8 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
MFG-E8, also known as lactadherin and MFGE8, contains 1 EGF-like domain and 2 F5/8 type C domains. It also contains phosphatidylserine (PS) binding domain, as well as an Arginine-Glycine-Aspartic acid motif, which enable... | |||
TMPY-01283 | Glypican 3/GPC3 Protein, Human, Recombinant (His) | Human | HEK293 |
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr... | |||
TMPY-00502 | Glypican 3/GPC3 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr... | |||
TMPY-01403 | VNN1 Protein, Human, Recombinant (His) | Human | HEK293 |
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one... | |||
TMPY-03547 | IL-10 Protein, Human, Recombinant | Human | E. coli |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-01845 | IL-10 Protein, Human, Recombinant (His) | Human | HEK293 |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-05064 | IL-10 Protein, Mouse, Recombinant | Mouse | E. coli |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-02358 | CD98 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPK-00856 | GUCY2C Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier functio... | |||
TMPK-01388 | GUCY2C Protein, Canine, Recombinant (aa 21-430, His) | Canine | HEK293 |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier functio... | |||
TMPK-00991 | GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier functio... | |||
TMPK-00990 | GUCY2C Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier functio... | |||
TMPK-01011 | TNFSF15 Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 |
TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or col... | |||
TMPK-01279 | GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His) | Cynomolgus | HEK293 |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier functio... | |||
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Cat No. | Product Name | ||
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L2540 | Gut Microbial Metabolite Library | 614 compounds | |
A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS; | |||
L6600 | Anti-Gastroenteritis Natural Product Library | 223 compounds | |
A unique collection of 223 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS); | |||
L7100 | Anti-Obesity Compound Library | 2286 compounds | |
A unique collection of 2286 anti-obesity compounds for high throughput and high content screening; |