cis-isomer — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10503	ACAT-IN-1 cis isomer		Acyltransferase
	ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases.		Acyltransferase
T6729	Lomibuvir	VX-222,VCH-222	HCV Protease
	Lomibuvir (VCH-222) (VX-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir...		HCV Protease
T8137	(Z)-Aconitic acid	Cls-Aconitic acid	Others , Endogenous Metabolite
	(Z)-Aconitic acid is the cis-isomer of Aconitic acid.is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.		Others , Endogenous Metabolite
T1109	(Z)-Capsaicin	Zucapsaicin,Civamide,cis-Capsaicin	TRP/TRPV Channel , HSV
	(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeutic efficacy in pain ac...		TRP/TRPV Channel , HSV
T37512	cis-4-Hydroxy-L-proline		Endogenous Metabolite
	cis-L-Hydroxyproline inhibits the synthesis and extracellular deposition of collagen. The growth inhibition of pancreatic cancer cells induced by the Hyp isomer could be due to endoplasmatic reticulum stress.		Endogenous Metabolite
T13415	Zuclomiphene citrate		Others
	Zuclomiphene citrate is a cis isomer of Clomiphene citrate, and has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer.		Others
T74451	13-cis-Retinyl acetate
	13-cis-Retinyl acetate (13-cis-Retinol acetate; 13-cis-Vitamin A acetate), a 13-cis isomer of Retinyl acetate, serves as an active metabolite of vitamin A [1].
T71819	RK-20448
	RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2. It also inhibits BLK, Csk, Fyn, and Lyn. RK-20448 is the cis isomer of A-419259
T40424	9-cis-Vitamin A palmitate	9-cis-Vitamin A palmitate,9-cis-Retinyl palmitate
	9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer resulting from the interaction of vitamin A palmitate in corn flakes. It exhibits a biological activity of 26% compared to all-trans-vitamin A palmita...
T75679	13-cis-Vitamin A palmitate
	13-cis-Vitamin A palmitate (13-cis-Retinyl palmitate), a derivative of vitamin A palmitate found in corn flakes, is the 13-cis isomer exhibiting 75% of the biological activity of all-trans-vitamin A palmitate, which is t...
T36236	5-cis Carbaprostacyclin
	5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. It is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 μM compared to 0.3 μM for carbaprostacyclin. 5-cis Carbapros...
T37213	5-trans Latanoprost
	Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been chan...
T83878	Z-CITCO
	Z-CITCO acts as an agonist for the constitutive androstane receptor (CAR; with an EC50 of 3.9 µM in human receptor reporter assays) and is the cis isomer of the CAR agonist CITCO.
T72436	cis,trans-Germacrone
	Cis,trans-Germacrone, an isomer of Germacrone, demonstrates extensive antitumor, antioxidant, and anti-inflammatory properties. It hinders lung cancer cell proliferation and impacts the Akt/MDM2/p53 pathway. Additionally...
T37214	5-trans Latanoprost (free acid)
	Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endog...
T73814	cis-Lomibuvir
	Cis-Lomibuvir (cis-VX-222), a cis-isomer of Lomibuvir, is a selective non-nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase (RdRp), targeting thumb pocket 2 with a dissociation constant (Kd) of 17 nM. I...
T37230	(+)-5-trans Cloprostenol
	Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horse...
T38220	11-cis Retinol
	11-cisRetinol is an isomer of vitamin A . It is formed from vitamin A,viaatrans-retinyl ester intermediate, by the enzyme RPE65 in the retinal pigment epithelium and then converted to 11-cis retinal as part of the visual...
T37547	Trans-Urocanic Acid
	trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes ...
T37911	cis-Resveratrol	(Z)-Resveratrol
	Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, ...