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  • Chloride channel
    (5)
  • CFTR
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cacc

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    5
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    1
    TargetMol | Peptide_Products
  • Dye Reagents
    1
    TargetMol | Dye_Reagents
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    TargetMol | Natural_Products
CaCCinh-A01
T4330407587-33-1
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).
  • $52
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T16Ainh-A01
T13059552309-42-9
T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1 µM),and functions as a calcium-activated chloride channel (CaCC).
  • $30
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TargetMol | Citations Cited
Crofelemer
SP 303, Provir, Crofelemer
T205474148465-45-6
Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.
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Kobusin
TN183436150-23-9
Kobusin, a bisepoxylignan compound isolated from Pnonobio biondii Pamp, demonstrates CFTR and CaCC chloride channel activation properties while exhibiting inhibitory effects on ANO1/CaCC channels.
  • $84
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GaTx2
TP2027194665-85-5
Very high affinity ClC-2 blocker (apparent KD ~ 50 pM). Slows ClC-2 activation and inhibits slow-gating but does not inhibit open ClC-2 channels. Selective for ClC-2 over other ClC family members (ClC-0, ClC-1, ClC-3 and ClC-4), CFTR, GABAC, CaCC and KV1.
  • $2,631
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