backbone — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T17155	Trabectedin	Ecteinascidin 743,ET-743	Apoptosis , Reactive Oxygen Species
	Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0...		Apoptosis , Reactive Oxygen Species
T13507	4,4'-Iminodiphenol	Leucoindophenol	Estrogen/progestogen Receptor
	4,4'-Iminodiphenol (Leucoindophenol) is an inactive estrogen receptor ligand with a diphenylamine backbone.		Estrogen/progestogen Receptor
T8240	Cis-5-Dodecenoic Acid		Others
	Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.		Others
T5658	Adamantane		Others
	The adamantane moiety is the structural backbone of numerous compounds and the physicochemical and biological properties of organic polyhedral compounds with practical application in the pharmaceutical industry.		Others
T6873	Lauric Acid	Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid	Others , Endogenous Metabolite , Antibacterial
	Lauric Acid (Dodecylic acid),which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coconut oil and palm kernel oi...		Others , Endogenous Metabolite , Antibacterial
T77504	JAK1/2/3 Inhibitor 1		PKA
	JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines. It inhibits the growth of cancer cells by binding to the c...		PKA
T2910	Flavonol	3-Hydroxyflavone,3-HF,Flavon-3-ol,3-Hydroxy-2-phenylchromone	Others , Endogenous Metabolite
	Flavonol (3-Hydroxyflavone) is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate, red raspberry, and fenugreek. 3-hydroxyflavone...		Others , Endogenous Metabolite
T4776	Glycerol	Glycerin	Endogenous Metabolite
	Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol...		Endogenous Metabolite
T16591	Propargyl-PEG1-SS-PEG1-PFP ester		Others
	Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T13729	Hydrolyzed Fumonisin B1	Aminopentol	Others
	Hydrolyzed Fumonisin B1 is the backbone and the main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase.		Others
T18488	NH2-MPAA-NODA		Others
	NH2-MPAA-NODA, a nitroveratryl-based photocleavable linker featuring a NODA motif and a methyl phenyl acetic acid (MPAA) backbone, serves as a radiolabel when labeled with 18F-fluoride.		Others
T38896	VPM peptide
	VPM peptide functions as a protease-cleavable dithiol cross-linker. It is capable of integration into the PEG-diacrylate (PEG-DA) macromer backbone, resulting in the formation of PEG hydrogel.
T76708	Penpulimab
	Penpulimab, an anti-PD-1 monoclonal antibody featuring an IgG1 backbone, possesses antitumor activities [1].
T15993	Mal-PEG4-PFP ester		Others
	Mal-PEG4-PFP ester is a non-cleavable antibody-drug conjugate (ADC) linker that incorporates a Maleimide moiety, a 4-unit Polyethylene Glycol (PEG) backbone, and a Pentafluorophenyl (PFP) ester.		Others
T40589	6-O-β-D-Galactopyranosyl-D-galactose
	6-O-beta-D-Galactopyranosyl-D-galactose, a disaccharide, is a constituent of the polysaccharide backbone characterized by beta-(1→6) glycoside linkages, with a side chain attached to the primary chain through a beta-(1→3...
T34180	Psilostachyin C	NSC 106392
	Psilostachyin c is a member of the class of compounds known as ambrosanolides and secoambrosanolides. Ambrosanolides and secoambrosanolides are sesquiterpene lactones from the Ambrosia family, with a backbone derivative ...
TN4592	Murrangatin		IL Receptor , TNF , COX , Prostaglandin Receptor
	Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity ag...		IL Receptor , TNF , COX , Prostaglandin Receptor
T34686	Sonoflora 1	SF 1,SF-1,Sonoflora1,Sonoflora-1,SF1
	Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Precli...
T38180	C16 Phytoceramide (t18:0/16:0)
	C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/1...
T14448	Azido-PEG4-CH2-Boc		Others
	Azido-PEG4-CH2-Boc is a four-unit cleavable polyethylene glycol (PEG) linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2]. This linker is characterized by its azide functional g...		Others