7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39578 | TPh A | Triphenyl Compound A | Others |
Triphenyl Compound A (TPh A) is an effective inhibitor of nuclear protein pirin, showing specific binding to pirin with a Ki value of 0.6 uM. Its mechanism of action involves disturbing the formation of the bcl3–pirin co... | |||
T14119 | ACT-678689 | Compound Example 1.53.4 | Hydroxylase |
ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1]. | |||
T10142 | P-Ethynylphenylalanine | 4-Ethynyl-L-phenylalanine | Others , Hydroxylase |
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM. | |||
T15779 | LP-533401 hydrochloride | 5-HT Receptor | |
LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis. | |||
T10142L | P-Ethynylphenylalanine hydrochloride | 4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base) | Hydroxylase |
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanine hydrochloride to inhibit selectively and reversibly the b... | |||
T69135 | AGN-2979 | Others | |
AGN-2979 is a tryptophan hydroxylase (TPH) activation inhibitor that shows antidepressant properties in rodent models of depression. | |||
T80960 | TPT-004 | Others | |
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating peripheral serotonin [1] and impeding colorectal tumor growth. |