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Results for "

KRas G12C inhibitor 2

" in TargetMol Product Catalog
  • Inhibitor Products
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KRas G12C inhibitor 2
T117772206735-61-5
KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.
  • $2,570
10-14 weeks
Size
QTY
Edg-2 receptor inhibitor 1
T45211195941-38-8
Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).
  • $98
In Stock
Size
QTY
PKM2 inhibitor G
T67900904457-46-1
PKM2 inhibitor G is a inhibitor of pyruvate kinase.
  • $195
In Stock
Size
QTY
cholesterol-absorption inhibitor Intermediate 2
T65554190595-65-4
cholesterol-absorption inhibitor Intermediate 2 is a potent and orally active cholesterol absorption inhibitor that reduces blood cholesterol levels.
  • $29
In Stock
Size
QTY
C-Met inhibitor D9
T67859299405-67-7
C-Met inhibitor D9 is a c-Met kinase inhibitor.
  • $195
In Stock
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QTY
TargetMol | Inhibitor Sale
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
T66256503614-91-3
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagulation factor Xa, and it can be used in the study of thrombophlebitis, atherosclerosis, cerebral embolism, stroke and pulmonary embolism.
  • $35
In Stock
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QTY
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2’-beta-C-Methyl inosine
TNU0442374750-32-0
2’-beta-C-Methyl inosine (2’-C-Methylinosine) is an HCV RNA polymerase inhibitor with antiviral activity and is being studied for the treatment of hepatitis C virus infection.
  • $173
7-10 days
Size
QTY
JAK1/2/3 Inhibitor 1
T7750416234-14-3
JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines. It inhibits the growth of cancer cells by binding to the cancer cell backbone and inhibiting the production of new proteins.
  • $50
In Stock
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QTY
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Cdk1/2 Inhibitor III
T14914443798-55-8In house
Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor with an IC50 value of 2.1 μM against CDK1/cyclin B.
  • $350
In Stock
Size
QTY
GSK-3β inhibitor 12
T60472784170-07-6
GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3β inhibitor 12 can be used for the study of Parkinson's in the presence of lipopolysaccharide induction.
  • $83
In Stock
Size
QTY
EGFR/ErbB-2 inhibitor-1
T798611135150-79-6In house
EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.
  • $195
In Stock
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QTY
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ACHE Inhibitor 12
T7735266309-83-9
ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.
  • $195
In Stock
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QTY
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mTOR kinase Inhibitor 2
T93151021917-65-6In house
2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- is a potent mTOR inhibitor with IC50 of 0.176 μM and >30 μM for mTOR and PI3Kα, respectively.
  • $148
In Stock
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QTY
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2′-C-Methyl-6-O-methylinosine
TNU0810565450-78-4
2′-C-Methyl-6-O-methylinosine (2′-C-Methyl-6-O-methylinosine) is a hypoxanthine analog with a wide range of physical activities for the study of a variety of tumor diseases.
  • $195
In Stock
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TbPTR1 inhibitor 2
T933417557-67-4
TbPTR1 inhibitor 2 is identified as a new development of improved pteridine reductase-1 (PTR1) inhibitors and anti-trypanosomatidic agents[1].
  • $38
In Stock
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QTY
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5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE
T891217899-49-9
5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.
  • $51
In Stock
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QTY
Cot inhibitor-2
T10866915363-56-3In house
Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM.
  • $93
In Stock
Size
QTY
MMP-12 Inhibitor
T600831258003-93-8In house
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
  • $195
Backorder
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QTY
TargetMol | Citations Cited
c-Fms-IN-2
T10775791587-67-2In house
c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).
  • $88
In Stock
Size
QTY
ERK1/2 inhibitor 1
T112262095719-90-5In house
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
  • $213
In Stock
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DGAT-1 inhibitor 2
T11016942999-61-3In house
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known DGAT enzymes that catalyze the final step of triglyceride synthesis. The discovery of transgenic mice and pharmacological studies indicate that inhibiting DGAT1 is a promising strategy for treating obesity and type 2 diabetes.
  • $59
In Stock
Size
QTY
KRAS G12C inhibitor 16
T117702349392-79-4In house
KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor with potential anticancer and antitumor activity, inhibits cancer cell proliferation, and can be used in the study of lung cancer.
  • $457
In Stock
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QTY
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c-Myc inhibitor 7
T720402883535-99-5In house
C-Myc Inhibitor 7, serving as both a c-Myc inhibitor and a multi-target protein degrader, effectively degrades proteins c-MYC, CK1α, GSPT1, and IKZF1/2/3 across various tumor cell types. It holds potential for research into diseases associated with high c-Myc expression, including cancer, cardiovascular and cerebrovascular conditions, and viral infections.
  • $1,520
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IRAK inhibitor 2
T7368928333-30-6In house
IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.
  • $78
In Stock
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Cysteine protease inhibitor-2
T10924612048-23-4In house
Cysteine protease inhibitor 2 is a cysteine protease inhibitor. Cysteine protease inhibitor 2 inhibited DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μM, respectively.
  • $1,520
6-8 weeks
Size
QTY
TargetMol | Inhibitor Sale
KRas G12C inhibitor 1
T117762158297-28-8In house
KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.
  • $1,670
8-10 weeks
Size
QTY
TargetMol | Inhibitor Sale
Menin-MLL inhibitor MI-2
T26491271738-62-5
Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
  • $35
In Stock
Size
QTY
TargetMol | Citations Cited
pan-KRAS-IN-2
T798002882825-14-9
Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12D, G12C, G12V, G12S, G12A, Q61H), while showing significantly reduced inhibition, with an IC50 >10 μM, for the KRAS G13D mutant [1].
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C-Peptide 2, rat acetate
T40518L
C-Peptide 2, rat acetate is a proinsulin component of inhibiting glucose-induced insulin secretion, consisting of acetate and a polypeptide composed of 31 amino acid residues [1] [2].
  • $195
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KRAS G12D inhibitor 7
T402822648552-34-3
KRAS G12D inhibitor 7, is a highly potent inhibitor specifically targeting KRAS G12D.
  • $970
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QTY
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Tuberculosis inhibitor 12
T80925793729-44-9
Tuberculosis Inhibitor 12, an oxadiazole derivative, effectively inhibits Mycobacterium tuberculosis, demonstrating inhibition rates of 82% and 78% at a concentration of 20 μM on 7H9-Tw-OADC media, respectively [1].
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VEGFR-2/c-Met-IN-1
T80874
VEGFR-2/c-Met-IN-1 is a dual inhibitor targeting VEGFR-2 and c-Met with respective IC50 values of 138 nM and 74 nM, demonstrating antitumor activity [1].
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Protein kinase G inhibitor-2
T9940612829-80-8
Protein kinase G inhibitor-2 exhibits antibacterial, antiviral, and antitumor activities.
  • $33
In Stock
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QTY
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IGF-1R inhibitor-2
T385021116236-15-7
IGF-1R inhibitor-2 (example 121) is a compound that inhibits the insulin-like growth factor-1 receptor (IGF-1R). By downregulating the IGF-1R, it has the potential to reverse the transformed phenotype of tumor cells and make them more susceptible to apoptosis.
  • $970
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HA-CD44 interaction inhibitor 2
T82244
Antitumor Agent-108 (Compound 5), an inhibitor of the Hyaluronic Acid (HA)-CD44 interaction, effectively disrupts cancer spheroid integrity and exhibits antiproliferative activity against cancer cells [1].
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KRAS mutant protein inhibitor 1
T402722642305-16-4
KRAS mutant protein inhibitor 1 is a KRAS mutant protein inhibitor for potential treatment in cancer.
  • $970
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TAO Kinase inhibitor 2
T77501850467-77-5
TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
  • $30
In Stock
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KRAS G12D inhibitor 17
T746632821793-99-9
KRAS G12D Inhibitor 17 (example 8), a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, acts as a proteolysis targeting chimera (PROTAC) [1], specifically inducing degradation of the G12D-mutation KRAS protein.
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11R,12-Dihydroxyspirovetiv-1(10)-en-2-one
TN259362574-30-5
11R,12-Dihydroxyspirovetiv-1(10)-en-2-one is a natural product for research related to life sciences. The catalog number is TN2593 and the CAS number is 62574-30-5.
  • $293
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Raf inhibitor 2
T4194220904-99-4
Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.
  • $39
In Stock
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PROTAC KRAS G12C degrader-1
T77926
PROTAC KRAS G12C degrader-1, a cereblon-based degrader, promotes CRBN/KRAS G12C dimerization and facilitates the degradation of GFP-KRAS G12C in reporter cells [1].
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C-2′-Decoumaroylaloeresin G
T827991059182-21-6
Compound 1059182-21-6 features a cyclic structure characterized by a nitrogen atom occupying an apex (corner) within the heterocycle. Its molecular scaffold integrates aromatic properties due to the presence of a conjugated system, while the inclusion of hydroxyl (-OH) groups confers reactive potential for subsequent modification. Additionally, a halogenated component, specifically a bromine atom, is attached to the aromatic ring, enhancing its propensity for undergoing further synthetic transformations.
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JAMM protein inhibitor 2 
T9892848249-35-4
JAMM protein inhibitor 2 (Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-) is an inhibitor of JAMM protease and can be used for anticancer studies. The IC50s are 10 μM, 46 μM, and 89 μM for thrombin, Rpn11, and MMP2, respectively.
  • $116
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2-C-methylene-myo-inositol oxide
T833904068-87-5
2-C-Methylene-myo-inositol oxide (NSC 45109), an inositol derivative, promotes pseudohyphal growth in Saccharomyces species [1].
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Protein kinase G inhibitor-1
T67755354544-70-0
Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.
  • $195
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KRAS G12C inhibitor 56
T723562749963-77-5
KRAS G12C inhibitor 56, a powerful inhibitor of SOS1 with an inhibitory concentration (IC50) of 1.6 nM, holds promise for use in cancer research.
  • $6,489
10-14 weeks
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Ajugasterone C 2-acetate
T83150154510-93-7
Ajugasterone C 2-acetate, an ecdysteroid extractable from Cyanotis arachnoidea [1], is a chemical compound.
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Bcl-2-IN-12
T829141383737-59-4
Bcl-2-IN-12 (Compound 1) is a potent Bcl-2 inhibitor with an IC50 value of 6 nM, utilized in cancer research [1].
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Multi-target kinase inhibitor 2
T81739
Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values between 40 to 204 nM. It exhibits cytotoxic effects on HepG2, HeLa, MDA-MB-231, and MCF-7 cell lines, with IC50 values of 41, 57, 51, and 59 μM, respectively. Additionally, it induces cell cycle arrest and apoptosis specifically in HepG2 cells.
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2-C-Methyl-D-erythritol
TN237958698-37-6
2-C-Methyl-D-erythritol is a natural product from the fruit of Carum ajowan
  • $320
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