20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2824 | Pedunculoside | Others , Fatty Acid Synthase | |
Pedunculoside is extracted from Ilex rotunda Thunb. | |||
T3941 | Choline Fenofibrate | Trilipix,ABT-335 | P450 , COX , PPAR |
Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. | |||
T2321 | Protodioscin | Furostanol I | Androgen Receptor , Endogenous Metabolite |
Protodioscin (Furostanol I) is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties. | |||
T4628 | Seladelpar | MBX 8025 | PPAR |
Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia. | |||
T24865 | Tenivastatin | L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid | ROS , HMG-CoA Reductase |
Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia. | |||
T27832 | Lifibrol | U 83860,K-12148,K-12.148,U-83860,K12148 | Lipid |
Lifibrol (U-83860) is an inhibitor of cholesterol synthesis.Lifibrol has anticholesterol and hypolipidemic properties and promotes the conversion of LDL Apo B-100 in patients with hypercholesterolemia and mixed hyperlipi... | |||
T1162 | Acipimox | Olbemox,K-9321 | Others |
Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients. | |||
T27245L | Eflucimibe | L0081,F-12511 | Acyltransferase |
Eflucimibe (L0081) is an acyl coenzyme A: cholesterol acyltransferase inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, and can be used to study atherosclerosis and hyperlipidem... | |||
T1604 | Tiratricol | 3,3',5-Triiodothyroacetic acid | Thyroid hormone receptor(THR) |
Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of A... | |||
T67974 | Berberine ursodeoxycholate | HTD1801,BUDCA | |
Berberine ursodeoxycholate (HTD1801) is an orally effective hypolipidemic agent, an ionic salt of Berberine and Ursodeoxycholic acid.Berberine ursodeoxycholate has a wide range of metabolic activity and significantly red... | |||
T72025 | PCSK9-IN-10 | Serine/threonin kinase | |
PCSK9-IN-10, a potent and orally active inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), exhibits a half-maximal inhibitory concentration (IC50) of 6.4 µM. By enhancing the expression of Low-Density Li... | |||
TN1011 | Rhodionin | P450 , AChE | |
Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs; they can significantly suppress the elevation of ... | |||
T3779 | Crocin II | Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B | Caspase , COX , NO Synthase |
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres... | |||
T3123 | Allicin | ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection | |
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus... | |||
T26819 | Binifibrate | WAC104,WAC 104,Antopal,WAC-104,Biniwas | |
Binifibrate is a hyperlipemiant drug used for the treatment of hyperlipidemia. | |||
T28825 | Sodelglitazar | GW677954,GSK-677954 | |
Sodelglitazar, a PPAR agonist, is used potentially for the treatment of hyperlipidemia and type 2 diabetes. | |||
T30110 | AR 12456 | AR12456,AR-12456 | |
AR-12456 is a Trapidil derivative that prevents serum hyperlipidemia in guinea pigs. | |||
T28820 | SMP-797 HCl | SMP-797,SMP 797,SMP797 | |
SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia. | |||
T23611 | Acetiromate | Adecol | |
Acetiromate is a drug of antilipidemic. It is used to treat hyperlipidemia. | |||
T11914 | LY88074 Trimethyl ether | Others | |
LY88074 Trimethyl ether is useful for inhibiting various conditions associated with estrogen deprivation syndrome, such as osteoporosis and hyperlipidemia. |