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Gap Junction Protein

Gap junctions are a specialized intercellular connection between a multitude of animal cell-types. They directly connect the cytoplasm of two cells, which allows various molecules, ions and electrical impulses to directly pass through a regulated gate between cells.One gap junction channel is composed of two connexons (or hemichannels), which connect across the intercellular space. Gap junctions are analogous to the plasmodesmata that join plant cells.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T7732 Carbenoxolone 5697-56-3 99.52%
Carbenoxolone
Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents th...
T78061 Peptide5 TFA 98%
Peptide5 TFA
Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury. Additionally, it s...
T11990 Meclofenamic acid 644-62-2 98%
Meclofenamic acid
Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic ac...
T19335 Danegaptide Hydrochloride 943133-81-1 99.55%
Danegaptide Hydrochloride
Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.
T16790L Rotigaptide TFA(355151-12-1 free base) T16790L 99.21%
Rotigaptide TFA(355151-12-1 free base)
Rotigaptide TFA(355151-12-1 free base) is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide TFA(355151-12-1 free base) prevents the uncoupl...
T0260 Meclofenamic acid sodium 6385-02-0 99.08%
Meclofenamic acid sodium
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prosta...
T5192 Gap 26 197250-15-0 98.26%
Gap 26
Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
T0992 Carbenoxolone disodium 7421-40-1 98.01%
Carbenoxolone disodium
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stoma...
TP1563 Gap19 1507930-57-5 98%
Gap19
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
T15711 Larazotide acetate 881851-50-9 95.53%
Larazotide acetate
Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.
TP1333 Gap 27 198284-64-9 100%
Gap 27
Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.
T0342 Carvedilol phosphate hemihydrate 610309-89-2 100%
Carvedilol phosphate hemihydrate
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
TP2110L TAT-Gap19 acetate TP2110L 98%
TAT-Gap19 acetate
TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis ...
Carbenoxolone
T7732
Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents th...
Peptide5 TFA
T78061
Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury. Additionally, it s...
Meclofenamic acid
T11990
Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic ac...
Danegaptide Hydrochloride
T19335
Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.
Rotigaptide TFA(355151-12-1 free base)
T16790L
Rotigaptide TFA(355151-12-1 free base) is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide TFA(355151-12-1 free base) prevents the uncoupl...
Meclofenamic acid sodium
T0260
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prosta...
Gap 26
T5192
Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
Carbenoxolone disodium
T0992
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stoma...
Gap19
TP1563
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
Larazotide acetate
T15711
Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.
Gap 27
TP1333
Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.
Carvedilol phosphate hemihydrate
T0342
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
TAT-Gap19 acetate
TP2110L
TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis ...
TargetMol