T27471 |
GSK299115A
|
864082-35-9
|
98%
|
|
GSK299115A is a selective ROCK1 Inhibitor. GSK299115A exhibits IC50 of 8nM, 620nM, 560nM for ROCK1, RSK1, p70S6K, respectively.
|
T27467 |
GSK270822A
|
864082-23-5
|
98%
|
|
GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.
|
T13714L |
GRK2-IN-1 hydrochloride (2055990-90-2 free base)
|
T13714L
|
98%
|
|
GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).
|
T13714 |
CCG258208
|
2055990-90-2
|
98%
|
|
GRKs-IN-1 has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).
|
T8913 |
1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID
|
260555-42-8
|
98%
|
|
1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.
|
T14989 |
CMPD101
|
865608-11-3
|
98%
|
|
CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits ...
|
T24850 |
Takeda103A
|
865609-72-9
|
98%
|
|
Takeda103A is the GRK2-dependent bovine tubulin oxidation effective inhibitor.
|
T3498 |
CCG215022
|
1813527-81-9
|
98%
|
|
CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, 5 and 1, respectively.
|
T1636 |
Paroxetine hydrochloride
|
78246-49-8
|
98%
|
|
Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression.
|
T9609 |
GRK5-IN-2
|
1642839-27-7
|
98%
|
|
GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of in...
|
T3513 |
GSK180736A
|
817194-38-0
|
98%
|
|
GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50: 30 μM), b...
|