T7497 |
C3a (70-77)
|
63555-63-5
|
98%
|
|
C3a 70-77 is an octapeptide corresponding to the COOH terminus of C3a.
|
T35387 |
TLQP-21 TFA
|
|
98%
|
|
|
T17250 |
W-54011
|
405098-33-1
|
98%
|
|
W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a...
|
T38332 |
Complement factor D-IN-2
|
1903742-34-6
|
98%
|
|
Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and...
|
TP2180L |
Compstatin control peptide acetate
|
|
98%
|
|
Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.
|
T9915 |
Eculizumab
|
219685-50-4
|
98%
|
|
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
|
TP1304 |
Compstatin
|
206645-99-0
|
98%
|
|
Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.
|
T7776 |
ADH-503
|
2055362-74-6
|
98%
|
|
ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.
|
T7497L |
C3a 70-77 2TFA(63555-63-5(free base))
|
T7497L
|
98%
|
|
C3a 70-77 2TFA is an octapeptide corresponding to the COOH terminus of C3a.
|
T38287 |
C3a Receptor Agonist
|
944997-60-8
|
98%
|
|
C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from bein...
|
T3638 |
Leukadherin-1
|
344897-95-6
|
98%
|
|
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendot...
|
T64388 |
3-Phenoxybenzaldehyde
|
39515-51-0
|
98%
|
|
3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.
|
T12851 |
SB290157 trifluoroacetate
|
1140525-25-2
|
98%
|
|
SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).
|
T10863 |
Complement C5-IN-1
|
2365402-67-9
|
98%
|
|
Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
|
T9316 |
JR14a
|
2411440-41-8
|
98%
|
|
JR14a is a potent antagonist of human complement C3a receptor.
|
T12506L1 |
PMX 205 acetate(514814-49-4 free base)
|
T12506L1
|
98%
|
|
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
|
T11154L |
EG01377 2HCl
|
2749438-61-5
|
98%
|
|
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HC...
|
T60151 |
CP-447697
|
1092847-21-6
|
98%
|
|
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
|
T9189 |
Iptacopan hydrochloride
|
1646321-63-2
|
98%
|
|
LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and...
|
T60161 |
CP-289
|
1349637-14-4
|
98%
|
|
CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.
|