Home Tools
Log in
Cart

Complement System

The complement system, also known as complement cascade, is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. It is part of the innate immune system, which is not adaptable and does not change during an individual's lifetime. The complement system can, however, be recruited and brought into action by antibodies generated by the adaptive immune system.
Cat. No. Product name CAS No. Purity Chemical Structure
T35387 TLQP-21 TFA 98%
T7497 C3a (70-77) 63555-63-5 98%
C3a 70-77 is an octapeptide corresponding to the COOH terminus of C3a.
T17250 W-54011 405098-33-1 98%
W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a...
T38332 Complement factor D-IN-2 1903742-34-6 98%
Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and...
TP2180L Compstatin control peptide acetate 98%
Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.
T9915 Eculizumab 219685-50-4
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
TP1304 Compstatin 206645-99-0 100%
Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.
T7776 ADH-503 2055362-74-6 100%
ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.
T7497L C3a 70-77 2TFA(63555-63-5(free base)) T7497L 100%
C3a 70-77 2TFA is an octapeptide corresponding to the COOH terminus of C3a.
T38287 C3a Receptor Agonist 944997-60-8 97.5%
C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from bein...
T3638 Leukadherin-1 344897-95-6 98.49%
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendot...
T12851 SB290157 trifluoroacetate 1140525-25-2 98.93%
SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).
T9316 JR14a 2411440-41-8 99.29%
JR14a is a potent antagonist of human complement C3a receptor.
T12506L1 PMX 205 acetate(514814-49-4 free base) T12506L1 99.4%
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
T60151 CP-447697 1092847-21-6 99.62%
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
T9189 Iptacopan hydrochloride 1646321-63-2 99.84%
LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and...
T60161 CP-289 1349637-14-4 99.85%
CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.
T0945 Cyclosporin A 59865-13-3 99.85%
Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhib...
T8509 Danicopan 1903768-17-1 99.88%
Danicopan (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Da...
T8223 Avacopan 1346623-17-3 99.9%
Avacopan is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by a...
TLQP-21 TFA
T35387
C3a (70-77)
T7497
C3a 70-77 is an octapeptide corresponding to the COOH terminus of C3a.
W-54011
T17250
W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a...
Complement factor D-IN-2
T38332
Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and...
Compstatin control peptide acetate
TP2180L
Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.
Eculizumab
T9915
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
Compstatin
TP1304
Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.
ADH-503
T7776
ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.
C3a 70-77 2TFA(63555-63-5(free base))
T7497L
C3a 70-77 2TFA is an octapeptide corresponding to the COOH terminus of C3a.
C3a Receptor Agonist
T38287
C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from bein...
Leukadherin-1
T3638
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendot...
SB290157 trifluoroacetate
T12851
SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).
JR14a
T9316
JR14a is a potent antagonist of human complement C3a receptor.
PMX 205 acetate(514814-49-4 free base)
T12506L1
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
CP-447697
T60151
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
Iptacopan hydrochloride
T9189
LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and...
CP-289
T60161
CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.
Cyclosporin A
T0945
Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhib...
Danicopan
T8509
Danicopan (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Da...
Avacopan
T8223
Avacopan is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by a...
1 2