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Anti-infection

Anti-infective is a general term that encompasses antibiotics, antifungals, antiprotozoans and antivirals.

Niranthin
TN466050656-77-4
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. Niranthin also exhibits anti-hepatitis B virus, antiinflammatory and antiallodynic actions.
  • $198
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Robinetin
TN2158490-31-3
Robinetin (3,3',4',5',7-Pentahydroxyflavone) exhibits potent antioxidant and antiradical activities, effectively inhibiting EYPC membrane lipid peroxidation and HbA glycosylation.
  • $43
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(+)-Aromadendrene
T8247489-39-4
(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.
  • $30
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Quercimeritrin
TN1041491-50-9
Quercimeritrin (Quercetin-7-O-beta-D-glucopyranoside) has antibacterial activity, it shows promising activity against Staphylococcus aureus.
  • $39
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2-Desoxy-4-epi-pulchellin
TN2755122872-03-1
2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).
  • $122
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Methyl rosmarinate
TN192899353-00-1
Methyl rosmarinate is a noncompetitive tyrosinase inhibitor isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase. It exhibits antioxidative and antifungal activities, and also inhibits tyrosinase, α±-glucosidase, and matrix metalloproteinase-1 (MMP-1).
  • $68
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Licoflavone B
TN186091433-17-9
Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities.
  • $128
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Isoschaftoside
T389752012-29-0
Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita.
  • $50
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Vincetoxicoside B
TN111322007-72-3
Vincetoxicoside B, isolated from Polygonum paleaceum Wall. Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.
  • $45
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Eurycomalactone
TN163723062-24-0
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα β and IκBα.
  • $147
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pimpinellin
T5776131-12-4
Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
  • $30
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Brevilin A
T467216503-32-5
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 μM) in Cancer Cells.Brevilin A induces apoptosis and autophagy via mitochondrial pathway and PI3K AKT mTOR inactivation in colon adenocarcinoma cell CT26.antitumour
  • $97
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Cefotaxime
T773363527-52-6
Cefotaxime is an inhibitor of penicillin binding protein.
  • $30
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Persicogenin
TN205828590-40-1
Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2 M phase in a dose-dependent manner.
  • $100
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5-Geranoxy-7-methoxycoumarin
TN31107380-39-4
5-Geranoxy-7-methoxycoumarin shows antifungal activity.
  • $106
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Dictamine
T5746484-29-7
Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells.
  • $30
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Myristicin
T9113607-91-0
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway. Myristicin can induce Apoptosis as characterised by alterations in the mitochondrial membrane potential, cytochrome c release, Caspase-3 activation, PARP-cleavage and DNA fragmentation.
  • $34
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Kaempferol 3-O-sophoroside
TN110819895-95-5
Kaempferol 3-O-sophoroside (Kaempferol 3-O-beta-sophoroside) has antibacterial and antiviral activities.
  • $76
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Penicillin G potassium
T5602113-98-4
Penicillin G potassium (Benzylpenicillin potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic.
  • $30
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Piperlonguminine
TN20855950-12-9
Piperlonguminine, an alkaloid amide isolated from the Piper species, exhibits anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal, and antibacterial activities. It inhibits Akt mTOR signaling, promotes autophagy, and mediates cancer cell death.
  • $44
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VASICINE
T49606159-55-3
Vasicine is oxytocic and abortifacient agents.Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. Vasicine can regulate the inflammatory reaction, have great potentials to develop safe medi
  • $68
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Octahydrocurcumin
T3S169236062-07-4
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahydrocurcumin exhibits potent cytotoxic effect (IC50 =19.46 ug mL) and shows high antimicrobial activity.
  • $42
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Fuziline
T3S063180665-72-1
Fuziline is a diterpene alkaloid found in Aconitum kusnezoffii and Aconitum carmichaelii.It is functionally related to an aconitane.
  • $37
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paulownin
T569113040-46-5
Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity.
  • $64
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