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Anti-infection

Anti-infective is a general term that encompasses antibiotics, antifungals, antiprotozoans and antivirals.

Niranthin
TN466050656-77-4
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. Niranthin also exhibits anti-hepatitis B virus, antiinflammatory and antiallodynic actions.
  • $198
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Licoflavone B
TN186091433-17-9
Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities.
  • $128
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Methyl rosmarinate
TN192899353-00-1
Methyl rosmarinate is a noncompetitive tyrosinase inhibitor isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase. It exhibits antioxidative and antifungal activities, and also inhibits tyrosinase, α±-glucosidase, and matrix metalloproteinase-1 (MMP-1).
  • $68
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Kumatakenin
TN18393301-49-3
Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol mL.
  • $129
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Quercimeritrin
TN1041491-50-9
Quercimeritrin (Quercetin-7-O-beta-D-glucopyranoside) has antibacterial activity, it shows promising activity against Staphylococcus aureus.
  • $39
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Hesperetin 7-O-glucoside
TN173331712-49-9
Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inhibition of the growth of Helicobacter pylori. Hesperetin 7-O-glucoside can reduce blood pressure in healthy volunteers.
  • $64
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Piperlonguminine
TN20855950-12-9
Piperlonguminine, an alkaloid amide isolated from the Piper species, exhibits anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal, and antibacterial activities. It inhibits Akt mTOR signaling, promotes autophagy, and mediates cancer cell death.
  • $52
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Robinetin
TN2158490-31-3
Robinetin (3,3',4',5',7-Pentahydroxyflavone) exhibits potent antioxidant and antiradical activities, effectively inhibiting EYPC membrane lipid peroxidation and HbA glycosylation.
  • $43
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Isoforsythiaside
T3S10881357910-26-9
Isoforsythiaside has antioxidant, and antibacterial activities.
  • $58
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Cefotaxime
T773363527-52-6
Cefotaxime is an inhibitor of penicillin binding protein.
  • $30
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Vincetoxicoside B
TN111322007-72-3
Vincetoxicoside B, isolated from Polygonum paleaceum Wall. Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.
  • $45
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Eurycomalactone
TN163723062-24-0
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα β and IκBα.
  • $147
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Kaempferol 3-O-sophoroside
TN110819895-95-5
Kaempferol 3-O-sophoroside (Kaempferol 3-O-beta-sophoroside) has antibacterial and antiviral activities.
  • $76
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(+)-Aromadendrene
T8247489-39-4
(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.
  • $81
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Bruceantinol
TN145353729-52-5
Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng mL.
  • $168
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Brevilin A
T467216503-32-5
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 μM) in Cancer Cells.Brevilin A induces apoptosis and autophagy via mitochondrial pathway and PI3K AKT mTOR inactivation in colon adenocarcinoma cell CT26.antitumour
  • $97
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5-Geranoxy-7-methoxycoumarin
TN31107380-39-4
5-Geranoxy-7-methoxycoumarin shows antifungal activity.
  • $106
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VASICINE
T49606159-55-3
Vasicine is oxytocic and abortifacient agents.Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. Vasicine can regulate the inflammatory reaction, have great potentials to develop safe medi
  • $68
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Myristicin
T9113607-91-0
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway. Myristicin can induce Apoptosis as characterised by alterations in the mitochondrial membrane potential, cytochrome c release, Caspase-3 activation, PARP-cleavage and DNA fragmentation.
  • $34
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Isoastilbin
TN177254081-48-0
Isoastilbin is a dihydroflavonol glycoside compound found in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg mL and possesses anti-acne and tyrosinase inhibition properties. Additionally, isoastilbin demonstrates neuroprotective, antioxidation, antimicrobial, and anti-apoptotic properties, indicating potential for Alzheimer's disease research.
  • $129
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Dictamine
T5746484-29-7
Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells.
  • $82
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Penicillin G potassium
T5602113-98-4
Penicillin G potassium (Benzylpenicillin potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic.
  • $39
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1,3,5,8-Tetrahydroxyxanthone
TN10842980-32-7
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta, exhibiting antispasmodic and anti-inflammatory activities. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method and significantly inhibits the growth of Staphylococcus aureus at a dose of 200 µg disk.
  • $89
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Delamanid
T4202681492-22-8
Delamanid (OPC-67683) is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall.
  • $39
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Antibacterial agent 27 
T961265795-51-9
Antibacterial agent 27 has potent anti-Candida activity.
  • $37
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paulownin
T569113040-46-5
Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity.
  • $64
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Persicogenin
TN205828590-40-1
Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2 M phase in a dose-dependent manner.
  • $100
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Heraclenin
TL00132880-49-1
Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat leukemia cells, it has a strong clastogenic effect . (+)-Heraclenin displays significant levels
  • $68
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2-(Hydroxymethyl)anthraquinone
TN121317241-59-7
2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg disc.
  • $80
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Octahydrocurcumin
T3S169236062-07-4
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahydrocurcumin exhibits potent cytotoxic effect (IC50 =19.46 ug mL) and shows high antimicrobial activity.
  • $42
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Nevadensin
T572210176-66-6
Nevadensin is an important herb-based constituent inhibiting estragole bioactivation. Nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat. It also exhibits inhibition activity against Mycobacterium tuberculosis, with equal MIC value of 200 microg mL.
  • $39
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Isoschaftoside
T389752012-29-0
Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita.
  • $50
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N-(Hydroxymethyl)nicotinamide
T78693569-99-1
N-(Hydroxymethyl)nicotinamide (Bilamid) is an antimicrobial agent.
  • $41
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Viridicatol
T1330514484-44-7
Viridicatol, with potent antibacterial activity against Staphylococcus aureus(MIC: 15.6 μg mL), is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum.
  • $77
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8-Geranyloxypsoralen
TN13437437-55-0
8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg L against B. xylophilus and is 117.5 mg L against P. redivivus.
  • $156
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Aspoxicillin
T1039263358-49-6
Aspoxicillin, a broad-spectrum antimicrobial agent, demonstrates efficacy against 68 isolates of Actinobacillus pleuropneumoniae, with a minimum inhibitory concentration (MIC90) of <= 0.05 μg ml. It exhibits a prolonged half-life of 55 minutes in mouse serum.
  • $33
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Sulfabrom
T16952116-45-0
Sulfabrom (Sulfabromomethazine) is a long-acting sulfonamide medicine for the treatment of coccidiosis and various bacterial infections in poultry, pigs, and cattle.
  • $43
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Ceftezole sodium
T785841136-22-5
Ceftezole sodium (Falomesin) is a broad-spectrum cephalosporin antibiotic active gram-negative and gram-positive bacteria except for Proteus vulgaris, Pseudomonas aeruginosa, and Serratia marcescens. It has the inhibition of cell wall synthesis via affinity for penicillin-binding proteins. It also inhibits alpha-glucosidase.
  • $35
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8-Epidiosbulbin E acetate
TN134291095-48-6
8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci.
  • $55
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7-Hydroxyflavanone
T79996515-36-2
7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates.
  • $35
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Baicalin methyl ester
TN142782475-03-4
Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).
  • $50
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5,7-DIMETHOXYFLAVONE
T577821392-57-4
5,7-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.
  • $34
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Prunin
TN2111529-55-5
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp. Prunin exhibits a markedly enhanced solubility compared to naringenin and naringin while maintaining the in vitro inhibition of HMG-CoA reductase.
  • $128
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Monocaprin
T96022277-23-8
Monocaprin is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
  • $31
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A 21960
T26408609-15-4
A 21960 (Ethyl 2-chloroacetoacetate) inhibits synapse formation between resolvase and two directly repeated res sites, blocks site-specific recombination reactions, and can be used to study bacterial infections.
  • $29
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pimpinellin
T5776131-12-4
Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
  • $30
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4-Acetamidobenzenesulfonamide
T8627121-61-9
4-Acetamidobenzenesulfonamide used in proteomics research and is an anti-infective agent
  • $31
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Pyromeconic acid
TL0015496-63-9
Pyromeconic acid (3-hydroxy-4H-pyran-4-one) and derivatives thereof are potent inhibitors of endonuclease
  • $30
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