tnfrsf-9

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9 4-1BBL, and possibly active during T cell activation. 4-1BB CD137 TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 25-38 kDa and the accession number is A9YYE7.

4-1BB CD137 TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A9YYE7.

4-1BB CD137 TNFRSF9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 26-35 KDa and the accession number is A9YYE7.

Expression system: HEK293 Cells
Length: 24-186, Extracellular Domain
Activity: BLI

Expression system: HEK293 Cells
Length: 24-186, Extracellular Domain
Activity: BLI、ELISA

Expression system: HEK293 Cells
Length: 24-186, Extracellular Domain
Activity: ELISA

Expression system: HEK293 Cells
Length: 24-186, Extracellular Domain
Activity: ELISA

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9 4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.

4-1BB CD137 TNFRSF9 Protein, Human, Recombinant (CHO, hFc) is expressed in CHO Cells. The accession number is Q07011.

4-1BB CD137 TNFRSF9 Protein, Human, Recombinant is expressed in E. coli. The accession number is Q07011.