timp-1

Expression system: HEK293 Cells
Length: 25-205, Full Length of Mature Protein
Activity: Not Tested

TIMP-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is P01033.

TIMP-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P01033.

TIMP-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P01033.

Expression system: HEK293 Cells
Length: 1-205, Full Length
Activity: Enzyme activity

TIMP-1 Protein, Rat, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.5 kDa and the accession number is P01860.

Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP‑1, TIMP‑2, TIMP‑3, and TIMP‑4. The TIMP-2 is detected in testis, retina, hippocampus and cerebral cortex. The function of TIMP 2 protein is to inhibit MMPs non covalently by the formation of binary complexes. Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.And the interaction with MMP-14 facilitates the activation of pro-MMP-2.It has been shown that the binding of TIMP 2 to a3b1 integrin results in the inhibition of endothelial cell proliferation and angiogenesis.

Expression system: HEK293 Cells
Length: 30-224, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 27-220, Full Length of Mature Protein
Activity: Not Tested

CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1 CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82 Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82 Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82 Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82 Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.