t807

T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).

L-Lysine hydrochloride, an essential amino acid for humans, offers numerous benefits including the treatment of herpes, reduction of diabetes-related illnesses, enhanced calcium absorption, and improved gut health.

S-Methyl-L-cysteine (S-Methylcysteine) is a natural product serving as a substrate in the methionine sulfoxide reductase A (MSRA) catalyzed antioxidant system, exhibiting neuroprotective, antioxidative, and anti-obesity properties.

Disodium succinate (Sodium succinate) is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxygen species.

Esafosfan trisodium (FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of sickle cell anemia, cardiovascular ischemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.

Dihydrojasmone is a natural product from bergamot

Gamma-decalactone (Decan-4-olide) is a food additive with a fruity peach flavor. Ricinoleic acid (12-hydroxy-octadec-9-enoic acid) is often used as a substrate in the production of γ-Decalactone.

α-Terpinyl acetate is a natural compound found in several essential oils, is a flavouring agent.

WAY-639228-A has potential antithrombotic and anticoagulant activity for the study of cerebral thrombosis.

β-Amyloid(17-28) human is a fragment of the β-amyloid peptide (Abeta) associated with Alzheimer's disease (AD), promoting the aggregation of the full-length β-Amyloid40 into toxic aggregates [1]. This lipid-induced amyloid core segment is implicated in AD pathogenesis.

β-Amyloid (1-16) rat is a fragment of the amyloid beta (Abeta) peptide's metal-binding domain, containing three amino acid substitutions compared to its human counterpart, which confer reduced susceptibility to Alzheimer's disease-like neurodegeneration in rats and mice [1].

α-Thevetin B (Compound 24), a cardiac glycoside extracted from Thevetia peruviana, has applications in research concerning lung, gastric, and pancreatic cancers [1].

α-Pompilidotoxin (α-PMTX), a neurotoxin sourced from Anoplius samanensis venom, reversibly and dose-dependently enhances excitatory postsynaptic currents (EPSCs), serving as a valuable tool in neuroscience research [1].

α-Isolupanine, an alkaloid found in Narrow-Leafed Lupin (Lupinus angustifolius L.), can be isolated for the study of anthracnose [1].

α-Hemolysin (Staphylococcus aureus), a polypeptide virulence factor of Staphylococcus aureus, disrupts host cell plasma membranes. Upon binding to the cell surface, its monomers create a homoheptamic prepore, which evolves into a mature transmembrane pore, facilitating K+ and Ca2+ ion transport that induces necrotic death in target cells [1].

α-Glucosidase-IN-42 (Compound 26), a 9-O-berberrubine carboxylate derivative, exhibits potent α-glucosidase inhibitory activity with an IC50 of 1.61 μM and has potential for use in antidiabetic research [1].

α-Glucosidase-IN-41 (compound 5o), a potent inhibitor of α-glucosidase, induces alterations in the enzyme's secondary structure, thereby impeding its catalytic function. This compound is utilized in the study of diabetes mellitus [1].

α-Glucosidase-IN-40 (compound 5) is a noncompetitive inhibitor of the α-glucosidase enzyme, with an inhibitory concentration (IC50) of 24.62 μM [1].

α-Glucosidase-IN-39 is a potent α-glucosidase enzyme inhibitor with an IC50 value of 869.06 ppm, applicable for antidiabetic studies [1].

α-Glucosidase-IN-38 (Compound 11j) is a potent α-glucosidase inhibitor with an IC50 of 12.44±0.38 μM, playing a significant role in Diabetes mellitus (DM) management [1].

α-Glucosidase-IN-37 (Compound 11) moderately inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages, with an IC50 value of 23.7 μM, and also shows weak inhibitory activity against α-Glucosidase [1].

α-Amylase-IN-4 (Compd 10y) exhibits the highest amylase inhibition with an IC50 value of 17.83 ± 0.14 μg/mL [1].

α-Amylase/α-Glucosidase-IN-6 (compound 5j) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50 values of 17.0 µM and 40.1 µM, respectively, and demonstrates anti-hyperglycemic activities [1].

Alpha,beta-Thujone, a constituent of various plant essential oils, has been linked to cancer development in male rats and can provoke seizures at maximal dosages [1].