synergistic effect

Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.

trans-Cyclohexane-1,2-diol (trans-1,2-Cyclohexanediol) has a synergistic retardation effect on percutaneous absorption and penetration of metronidazole (MTZ).

Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing factor (AIF) and Bax while inhibiting Keap1-Nrf2 [1].

Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely the major contributors to the notable synergistic antioxidant activity when coupled with pea pr

Corianin and coriatin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm.

Coriatin and corianin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm.

Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes, they demonstrate strong anti-leishmanial efficacies in BALB c mice model of leishmaniasis, suggests that these two compounds potential anti-leishmanial candidates. The

Isoreserpiline, an indole alkaloid discovered in R. tetraphylla, exhibits a range of biological activities. This compound enhances the antibacterial efficacy of nalidixic acid against both nalidixic acid-sensitive and -resistant E. coli strains through a synergistic effect. Additionally, at a dosage of 25 mg kg, it mitigates amphetamine-induced hyperactivity in mice.