s.aureus

Lauric Acid (Dodecylic acid),which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coconut oil and palm kernel oil.

Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2 ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.

Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.

XT-1, an antimicrobial peptide sourced from Xenopus tropicalis skin secretions, exhibits potent activity against S. aureus, E. coli, and C. albicans, with minimum inhibitory concentration (MIC) values of 5, 6, and 50 μM, respectively [1].

MCF, an antimicrobial peptide originating from bee venom, exhibits activity against E. coli W 160-37, S. aureus 8530, and B. subtilis, with minimum inhibitory concentration (MIC) values of 35-45 μg ml, 25-35 μg ml, and 15-25 μg ml, respectively [1].