quinidine

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

O-Desmethyl Quinidine is a novel quinidine analog with significant antiarrhythmic activity and low acute toxicity that may be useful in the treatment of cardiac arrhythmias.

Quinidine hydrochloride is the salt form of Quinidine and possesses antiarrhythmic and antiparasitic properties. This compound is used in the treatment of certain types of irregular heartbeats (arrhythmias) and malaria.

Quinidine-D3 (Standard) is a reference standard of Quinidine-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Quinidine-d3 is the deuterated form of Quinidine, an established antiarrhythmic agent and potent potassium-channel blocker with an IC50 of 19.9 μM. Quinidine-d3 retains inhibitory activity toward CYP450db and is employed in pharmacokinetic analyses, ion-channel research, and studies of antimalarial mechanisms.

Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.

Ep vinyl quinidine (3-Epiquinine) is an epi-vinyl stereoisomer of Quinidine, which is used in malaria research and acts as an antiarrhythmic agent. Quinidine is a potent, orally active, selective inhibitor of cytochrome P450db and a blocker of K+ channels with an IC50 of 19.9 μM [1] [2] [3].

Quinidine Monosulfate is an antiarrhythmic agent and a potent, orally active, selective cytochrome P450db inhibitor. Additionally, it functions as a K+ channel blocker with an IC50 of 19.9 μM, and can be used for malaria research [1] [2] [3].

Quinidine polygalacturonate is a potent, selective, orally active inhibitor of cytochrome P450db (cytochrome P450db) and a potent K+channel blocker with an IC50 value of 19.9 μM, which also induces apoptosis. Quinidine polygalacturonate is an anti-arrhythmic agent that can also be used in malaria research.

Quinidine hydrochloride monohydrate is an optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. It prolongs cellular action potential and decreases automaticity. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.

Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor

Quinidine sulfate is a useful organic compound for research related to life sciences and the catalog number is T124756.

Quinidine methiodide is a quaternized derivative of quinidine and a classical ion channel blocker. Unable to penetrate the blood-brain barrier, it prolongs action potential duration by exclusively blocking voltage-gated sodium and potassium channels on peripheral membranes, acting as a benchmark tool in neuromuscular and cardiovascular electrophysiology research.

(3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.

Quinidine-D3 is the deuterated form of Quinidine (TMSM-2361), an established antiarrhythmic agent and potent potassium-channel blocker with an IC50 of 19.9 μM. Quinidine-D3 retains inhibitory activity toward CYP450db and is employed in pharmacokinetic analyses, ion-channel research, and studies of antimalarial mechanisms.

Quinidine (Standard) is a reference standard for research and analysis in studies involving Quinidine. Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.

Hydroquinidine (Standard) is a reference standard for research and analysis in studies involving Hydroquinidine. Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.

Epiquinidine, an analogue of quinine, serves as an agonist for ggTas2r1, exhibiting activation at concentrations of 10 μM or higher.

Acebutolol hydrochloride (Acebutolol HCl) acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol hydrochloride is the hydrochloride salt form of acebutolol, a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Having stabilizing and quinidine-like effects on cardiac rhythm, Acebutolol hydrochloride is used in ventricular arrhythmias. Other indications include hypertension, alone or in combinations with other agents.

Viquidil hydrochloride (Quinotoxine hydrochloride) is an isomer of Quinidine. Viquidil hydrochloride is an agent of cerebral vasodilator with antithrombotic activity.

Quinine hemisulfate is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinine hemisulfate is also a blocker of K + channel with an IC 50 of 19.9 μM. Quinine hemisulfate has potential to be used for malaria research [1] [2] [3].

Acebutolol is a cardioselective beta-1 adrenergic antagonist with antiarrhythmic and hypotensive activity and little effect on the bronchial receptors. Acebutolol has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympa

DA 1686 is a therapeutic antiarrhythmic compound.DA 1686 reduces the tachycardic effects of aconitine. It also reduces the effects of increased frequency of electrical stimulation and is 1.8 times more active than quinidine and 9 times more active than procainamide.

Quinidine is a potent, orally active, selective inhibitor of cytochrome P450db. Quinidine hydrobromide is a K + channel blocker (IC 50= 19.9 μM). Quinidine hydrobromide shows antiarrhythmic activity. Quinidine hydrobromide can be used for malaria research.