mes-sa

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor

Galanin message-associated peptide (1-41) amide is a peptide hormone [1].

Hydrocinchonine is reported to have multidrug resistance reversal activity, which can weaken drug resistance by inhibiting the function of P-gp and possibly affecting its expression. In MES-SA/DX5 cells, the combination of Hydrocinchonine and Paclitaxel can enhance the apoptosis.

RJ-34, an aristolactam analogue, demonstrates strong antitumor effects across a wide range of cancer cell lines, with subnanomolar GI 50 values (GI 50 <0.1 nM) observed for A431, MES-SA, MES-SA/DX5, HCT-15, and HCT-15/CLO2 cells [1].

Tubulin polymerization-IN-63 (compound 6) is an inhibitor of tubulin polymerization. It exhibits an IC50 value of 0.29 μM against MES-SA cells, making it suitable for use in cancer research.