Search Result

Search Results for " lipolysis "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T31976	Glymidine sodium		Others
	Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion.		Others
T9753	LEI110		Phospholipase
	LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT).		Phospholipase
T1162	Acipimox	Olbemox,K-9321	Others
	Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.		Others
T77621	Z16078526		p38 MAPK , Mitochondrial Metabolism
	Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes. Additionally, it activates thermogenic gen...		p38 MAPK , Mitochondrial Metabolism
T1875	Atglistatin		Lipase
	Atglistatin is a highly effective, specific and competitive ATGL inhibitor with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, and no toxicity when the concentration up to 50 μM.		Lipase
T15432	GSK256073		GPR , Others
	GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inh...		GPR , Others
T10830	CL 316243		Adrenergic Receptor
	CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL3162...		Adrenergic Receptor
T62656	GPR81 agonist 1		GPR
	GPR81 agonist 1 is a potent and selective GPR81 agonist with high affinity for human and mouse GPR81.GPR81 agonist 1 inhibits lipolysis of differentiated 3T3-L1 adipocytes, improves insulin sensitivity and glycaemic cont...		GPR
T73499	NG-497	NG497	Lipase
	NG-497 is a selective, small molecule inhibitor of human adipose triglyceride lipase (ATGL) that targets the enzymatically active patatin-like structural domain of human ATGL.NG-497 binds ATGL in a hydrophobic lumen adja...		Lipase
TP1219	Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate	ANP (1-28), human, porcineANP(1-28)

TP2267	Lys-γ3-MSH(human)	Lys-γ3-MSH	Others
	Pro-opiomelanocortin (POMC) derived peptide that stimulates lipolysis		Others
T19338	Gelucire 44/14	Gelucire 14/44	Others
	Gelucire 44/14 (Gelucire 14/44) acts as a nonionic surface-active excipient and improves fat absorption in rats with impaired lipolysis.		Others
T26935	C108297	C-108297,C 108297
	C108297 is a glucocorticoid receptor modulator. C108297 prevents both diet-induced obesity and inflammation. C108297 decreased food and fructose intake and increased lipolysis in white adipose tissue (WAT) and free fatty...
T61464	TRβ agonist 2
	TRβ agonist 2 (Compound 1) is a highly potent agonist of TRβ. Moreover, it effectively reduces lipid accumulation in HepG2 cells and promotes lipolysis, offering comparable effects. With its promising attributes, TRβ ago...
T82732	Cholecystokinin (1-21)	CCK-1-21
	Cholecystokinin (1-21) (CCK-1-21), a fragment of cholecystokinin (CCK), induces lipolysis in human adipose tissue [1].
T75849	Lys-γ3-MSH(human) TFA
	Lys-γ3-MSH(human) TFA, a melanocortin peptide originating from the C-terminal fragment of pro-opiomelanocortin (POMC), enhances the steroidogenic response of rat adrenal glands to adrenocorticotrophin (ACTH). It is a pot...
T60925	TRβ agonist 3
	TRβ agonist 3 (Compound 3) is a potent TRβ agonist that is a new potential TRβ-selective thyromimetics. In vitro investigation, TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis [1].
T72745	Acipimox sodium	K-9321 sodium
	Acipimox (K-9321) sodium, a nicotinic acid analogue, functions as an antilipolytic agent by stimulating leptin release, inhibiting lipolysis, and reducing systemic free fatty acids (FFAs) levels, thereby enhancing insuli...
T27228	E-3030 free acid	E-3030,E3030,E 3030
	E-3030 free acid is a peroxisome proliferator-activated receptor (PPAR) agonist. E-3030 decreased blood glucose, triglyceride, non-esterified fatty acids, and insulin levels and increased blood adiponectin levels. Trigly...

Compounds

Target: Phospholipase

Acipimox

T1162

Synonym: Olbemox,K-9321

Target: p38 MAPK, Mitochondrial Metabolism

Target: Adrenergic Receptor

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

TP1219

Synonym: ANP (1-28), human, porcineANP(1-28)

Synonym: Gelucire 14/44

Target: Others

C108297

T26935

Synonym: C-108297,C 108297

Cholecystokinin (1-21)

T82732

Synonym: CCK-1-21

Target:

Lys-γ3-MSH(human) TFA

Synonym: K-9321 sodium

Target:

E-3030 free acid

T27228

Synonym: E-3030,E3030,E 3030

Target:

Cat No.	Product Name	Synonyms	Targets
T4S0227	Sinensetin	Pedalitin permethyl ether	TNF , PGE Synthase
	Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.		TNF , PGE Synthase
T8209	Saikosaponin b3		Others
	Saikosaponin b3 is isolated from the roots of Bupleurum falcatum L.. Saikosaponin b3 inhibits ACTH-induced lipolysis in the fat cells and exhibits analgesic effects.		Others
T19924	Rhododendrol	Betuligenol,Frambinol	Others
	Rhododendrol (Frambinol) is a melanin synthesis and acts by preventing high-fat diet-induced elevation in body weight and increasing lipolysis in white adipocytes in male mice. Rhododendrol can be used as the lightening/...		Others
T81013	Tert-OMe-byakangelicin
	Tert-OMe-byakangelicin is a coumarin known to potentiate adrenaline-induced lipolysis and impede insulin-mediated triglyceride synthesis from glucose in adipocytes [1].
T3S0964	Thermopsoside	Chrysoeriol-7-O-glucoside	Others
	Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system.Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border m...		Others
T79949	Foenumoside B		PPAR
	Foenumoside B, a triterpene saponin extracted from Lysimachia foenum-graecum, stimulates AMPK signaling, suppresses PPARγ-induced adipogenesis, and promotes lipolysis, shifting lipid metabolism. This compound is utilized...		PPAR

Natural Products

Sinensetin

T4S0227

Synonym: Pedalitin permethyl ether

Target: TNF, PGE Synthase

Synonym: Betuligenol,Frambinol

Target: Others

tert-OMe-byakangelicin

Synonym: Chrysoeriol-7-O-glucoside

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-01010	PLA2G16 Protein, Human, Recombinant (His)	Human	E. coli
	Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differenti...
TMPH-02516	APOC3 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density...
TMPH-02420	APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar)	Cynomolgus	Yeast
	Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density...
TMPY-03117	Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His)	Human	HEK293
	Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can st...
TMPH-01768	VGF Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	Secreted polyprotein that is packaged and proteolytically processed by prohormone convertases PCSK1 and PCSK2 in a cell-type-specific manner. VGF and peptides derived from its processing play many roles in neurogenesis a...
TMPY-02167	Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293)	Mouse	HEK293
	Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement ...
TMPY-02081	PDE2A Protein, Human, Recombinant (aa 215-900, His)	Human	Baculovirus-Insect Cells
	cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 sub...
TMPY-02183	Complement Factor D/CFD Protein, Human, Recombinant (His)	Human	HEK293
	Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement ...
TMPH-03500	IL-6 Protein, Sheep, Recombinant (GST)	Sheep	E. coli
	Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...
TMPH-03208	IL-6 Protein, Rabbit, Recombinant (His)	Rabbit	Yeast
	Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...