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Itacitinib (INCB039110) is an orally bioavailable Janus-associated kinase 1 (JAK1) inhibitor with potential antineoplastic activity.

Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets.

4-Octyl Itaconate, a cell-permeable derivative of Itaconate, is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 and inhibits phosphorylation of STING.

Itaconic anhydride (ITA) is a biobased material that is obtained from renewable resources. It is widely used in metal adhesion promoter, synthetic resin improver, esterification agent, herbicide, insecticide.

Monoethyl itaconate, a free radical, can be utilized for polymerization.

Dimethyl Itaconate is a chemical reagent used in the synthesis of functionalized 2-isoxazolines used in fragment-based drug discovery.

Itaconic acid is a precursor for the synthesis of polymers, chemicals, and fuels, and has anti-inflammatory activity.Itaconic acid can be synthesized by fungi. It is also a macrophage-specific metabolite. It mediates crosstalk between macrophage metabolism and peritoneal tumors.

Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2 STAT3 with anti-cancer activity.

Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inhibitor of HIF-1 and provide new perspectives into the mechanism of its anticancer activity. Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung Y cells.

Hexanorcucurbitacin F is a useful organic compound for research related to life sciences. The catalog number is T123847 and the CAS number is 96253-53-1.

Vitacoxib is a selective inhibitor of COX-2. It is used as a novel nonsteroidal anti-inflammatory agent.

2-epi-Cucurbitacin B, a natural product, is derived from Ecballium elaterium L. XVI. [1].

16,25-Di-O-acetylcucurbitacin F is a natural product for research related to life sciences. The catalog number is TN5988 and the CAS number is 2062685-10-1.

Cucurbitacin V is a natural product for research related to life sciences. The catalog number is TN5990 and the CAS number is 152340-37-9.

3-epi-Isocucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5972 and the CAS number is 89647-62-1.

Neocucurbitacin A (compound 7), a STAT3 inhibitor extracted from the pericarp of Aquilaria crassna, serves as a potential agent for anticancer research [1].

Cucurbitacin R is a useful organic compound for research related to life sciences and the catalog number is T124655.

2-O-β-D-Glucopyranosylcucurbitacin F 25-acetate, a cucurbitacin glucoside, can be isolated from the polar fractions of the MeOH extract of Cigarrilla mexicana [1].

Isocucurbitacin B has significant activities against HeLa and HT-29 human cancer cells with IC50 values ranging from 0.93 to 9.73uM.

16-Desoxycucurbitacin V is a natural product for research related to life sciences. The catalog number is TN5993 and the CAS number is 2081098-85-1.

Cucurbitacin B 2-o-α²-D-glucoside has anticancer activity.

7β-Hydroxycucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5978 and the CAS number is 1135141-79-5.

Isocucurbitacin D is a compound recognized for its antitumor properties [1].

23,24-Dihydroisocucurbitacin D (compound 22) is a member of the cucurbitacins [1].