inh 1

INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.

ODN INH-1, a palindromic and class R ('restricted') inhibitory ODN, is a potent inhibitor of TLR9-induced B cells and macrophages.

T3Inh-1 is a potent and selective ppGalNAc-T3 inhibitor with IC50 of 7 µM. T3Inh-1 protects against breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in tissue cells and mice without causing any toxic side effects.

Inh2-B1 is an inhibitor targeting STK1 (Ser/Thr protein kinase) by directly binding to its ATP-binding catalytic domain. STK1 is a crucial component in the cell wall biosynthesis of Staphylococcus aureus and a key factor in MRSA resistance. Consequently, Inh2-B1 is regarded as an "antibiotic resistance breaker" with the ability to prevent biofilm formation.

UTA1inh-A1 is a novel inhibitor of kidney urea transporter UT-A1.

UTA1inh-B1 is a novel inhibitor of kidney urea transporter UT-A1.

UTA1inh-C1 is a novel inhibitor of kidney urea transporter UT-A1.

UTA1inh-D1 is a novel inhibitor of kidney urea transporter UT-A1 .

PAT1inh-B01, a selective SLC26A6 inhibitor, impedes PAT1 (a Cl-/HCO3- exchanger) activity, with an IC50 of 350 nM, effectively inhibiting anion exchange. It also obstructs fluid absorption in the small intestine and is utilized in the study of small intestinal hyposecretory disorders [1].

PAT1inh-A0030 is a selective inhibitor of PAT1 (SLC26A6) with an IC 50 value of 1.0 μM. It inhibits fluid absorption in the ileum of wild-type and cystic fibrosis (CF) mice (CftrdelF508/delF508) in a closed-loop model of intestinal fluid absorption and can be used in the study of intestinal diseases related to CF [1].

4-aminobenzoic acid is an organic acid with UV-absorbing and antifibrotic properties. When exposed to light, 4-aminobenzoic acid absorbs UV light and releases excess energy through a photochemical reaction, which may cause DNA damage.4-aminobenzoic acid also increases oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote serotonin degradation, which in excess may lead to fibrotic Changes.

INH154 is a highly potent inhibitor of Nek2 and Hec1 binding (INH), with IC50 values of 120 nM in MB468 cells and 200 nM in Hela cells.

Ajugamarin H1 is a natural product that can be used as a reference standard.

4-Aminobenzoic acid (PABA) potassium is a modulator of catecholamine oxidation reactions. It holds promise for research in Parkinson's disease and hypertension.

CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.

Prostaglandin H1 is the cyclooxygenase metabolite of DGLA, a CRTh2 agonist and a precursor of a family of 1 anti-inflammatory prostaglandins. Prostaglandin H1 can be used in the study of inflammation.

INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).

Sanguiin h 11 is a compound purified from the plant Sanguisorba officinalis and has proven to be a potent inhibitor of chemoattractant-dependent and independent neutrophil movement.

MK-8712 is a monobactam beta-lactamase inhibitor.

INH-13 is a Aurora inhibitor.

Maximin H1, an antimicrobial peptide sourced from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits efficacy against several pathogens, including Escherichia coli (ATCC25922), Staphylococcus aureus (ATCC2592), Bacillus pyocyaneus (CMCCB1010), and Candida albicans (ATCC2002). Corresponding minimum inhibitory concentration (MIC) values are 9, 4.5, 9, and 4.5 μg/ml, respectively [1].

Bombinin H1, an antimicrobial peptide originating from the skin of the Bombina variegata moth, exhibits lethal concentrations of 3.8 μM against Escherichia coli D21 and 2.1 μM against Staphylococcus aureus Cowan 1 [1].

Biotin-H10 is a potent inhibitor of anterior gradient homolog 2 (AGR2) with a dissociation constant (K_D) of 6.4 nM, effectively reducing the viability of cancer cells [1].

Monamycin H1 is an ester peptide antibiotic that exhibits activity against Gram-positive bacteria.