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Results for "

hepatotoxic

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    26
    TargetMol | Inhibitors_Agonists
  • Natural Products
    18
    TargetMol | Natural_Products
  • Disease Modeling
    1
    TargetMol | Disease_Modeling_Products
Retrorsine
TN2147480-54-6
Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the research of hepatocellular injury.
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7-10 days
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Punicalin
T4S171865995-64-4
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg ml (0.14 microM).
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Flavokawain B
Flavokavain B, Flavokawin B, 2'-Hydroxy-4',6'-Dimethoxychalcone
T6S07351775-97-9
1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK NF-κB and MAPK signaling pathways. 3. Flavokawain B induces apoptosis, has the potential usefulness of FKB for prevention and treatment of hormone-refractory prostate cancer in an adjuvant setting. 4. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells.
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Ligularine
T2572434429-54-4
Ligularine is a hepatotoxic otonecine-type pyrrolizidine alkaloid isolated from Ligularia hodgsonii, a Chinese traditional antitussive medicine.
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4,5-Dicaffeoylquinic acid
3,4-Dicaffeoylquinic acid, Isochlorogenic acid C
T2S115857378-72-0
1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.
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Plantamajoside
Y0160, C10485
T3409104777-68-6
Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity.
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Silychristin
Silicristin
T387933889-69-9
Silychristin (Silicristin) is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase.
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Trichodesmine
T40627548-90-3
Trichodesmine, a dehydropyrrolizidine alkaloid, exhibits hepatotoxic, pneumotoxic, and neurotoxic effects in vivo.
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7-Acetylintermedine
T4085674243-01-9
7-Acetylintermedine is a hepatotoxic botanical pyrrolizidine alkaloid.
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Brazilin
Natural Red 24, Braziletto, Brasilin, Superbresiline
T6S1784474-07-7
1. Brazilin (Braziletto) exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific signaling pathway. 3. Brazilin has anti-inflammatory property, can suppress mastitis and high glucose-induced vascular inflammatory process related with the inhibition of oxidative stress, CAMs expression, and NF-κB activation in HUVEC; may be useful to treat chronic inflammatory disorders including rheumatoid arthritis.
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Microcystin-WR
T81795138234-58-9
Microcystin-WR, a hepatotoxic metabolite derived from cyanobacteria, has been demonstrated to induce hepatotoxicity in mice [1].
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Adonifoline
(+)-Adonifoline
TL0011115712-88-4
Adonifoline is a hepatotoxic pyrrolizidine alkaloid.
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7-10 days
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Seneciphylline
TN1078480-81-9
Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduc
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Aflatoxin G1
TN13591165-39-5
Aflatoxin G1 is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus, which is hepatotoxic, teratogenic, immunosuppressive, and carcinogenic, and is mainly found in contaminated cereals. Aflatoxin G1 inhibits RNA polymerase activity, affects RNA and protein synthesis, and causes damage to the liver and kidney.
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7-10 days
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6-O-(3'',4''-Dimethoxycinnamoyl)catalpol
TN3180147714-71-4
6-O-(3'',4''-Dimethoxycinnamoyl)catalpol has anti-hepatotoxic activity.
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Desacetyldoronine
TN3835120481-77-8
Desacetyldoronine is a hepatotoxic pyrrolizidine alkaloid.
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Jaconine
TN4346480-75-1
Jaconine, jacoline,jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer.
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Erucifoline N-oxide
TN7344123864-94-8
Erucifoline N-oxide, isolated from Senecio persoonia, exhibits hepatotoxic activity [1].
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