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Search Result

Search Results for " hepatic "

155

Compounds

61

Natural Products

72

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T83064 Anti-hepatic fibrosis agent 2
Compound 6k, also known as Anti-hepatic fibrosis agent 2, is an orally active inhibitor of the COL1A1 enzyme and exerts anti-fibrogenic effects by targeting the Ewing sarcoma breakpoint region 1 (EWSR1)[1].
TD0093 Oil Red O Others
The dry dye Oil red O is used for the preparation of a staining solution that can be used for the detection of lipids in histological cryo sections.
T12580 PTUPB COX , Epoxide Hydrolase
PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).
T12490 Pitavastatin lactone Others
Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes.
T13173 TMPA Others , AMPK
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.
T4410 LM10 Others
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters....
T31976 Glymidine sodium Others
Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion.
T1403 Climbazole BAY-e 6975 Antibiotic , Antifungal
Climbazole (BAY-e 6975) is a broad-spectrum imidazole antifungal agent with anti-dandruff benefits.
T5045 GSK4112 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452 Autophagy
GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.
T3124 Carbendazim Bavistin,Carbendazole,Mercarzole Antifungal
Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...
T0462 Cilostazol OPC 21,OPC 13013 PDE , Autophagy
Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.
T0850 Primaquine diphosphate Primaquine phosphate,Primaquine bisphosphate Antibiotic , Parasite
Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the proper...
T9195 SHR0302 ARQ252 Apoptosis , JAK
SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).
T1410 Torsemide AC-4464,JDL-464,Torasemide Na-K-Cl cotransporter
Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and h...
T8364 Mebrofenin SQ 26962 Others
Mebrofenin (SQ 26962) is available as a ready to use the kit for radio-labeling with Tc-99m.Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to...
T2096 Framycetin sulfate Neomycin Sulphate B,Framycetin sulphate Antibacterial , Antibiotic
Framycetin sulfate (Neomycin Sulphate B) belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds.
T1602 Valproic acid sodium salt Sodium Valproate Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha...
T6474 Divalproex Sodium Valproate semisodium,Epival HDAC
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...
T6595 Moexipril hydrochloride Moexipril HCl,RS-10085,SPM 925,CI-925 Apoptosis , RAAS
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.
T60004 SRI-37330 Others
SRI-37330 inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis.
T10409 ATX inhibitor 5 PDE
ATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor (IC50 : 15.3 nM) that reduces the level of CCl4-induced hepatic fibrosis and has anti-hepatic fibrosis effects,.
T19694 Hydronidone F351,F-351,F 351 Others
Hydronidone (F-351) is Non-Steroidal Antiinflammatory Drugs. It potentially for the treatment of hepatic fibrosis.
T6807 Citiolone Thioxidrene,Citiolase Others
Citiolone (Thioxidrene) is a thiolic-derived medication as a mucolytic agent for the treatment of certain hepatic disorders.
T13601 CDD3506 1-TRITYL-1H-IMIDAZOL-4-AMINE P450
CDD3506 (1-TRITYL-1H-IMIDAZOL-4-AMINE) increases high-density lipoprotein cholesterol by targeting hepatic CYP3A.
T19783 Dehydroabiethylamine NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine P450 , PDK
Dehydroabiethylamine (NSC-2955) is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.
T13600 CDD3505 4-nitro-1-trityl-1H-imidazole P450
CDD3505 (4-nitro-1-trityl-1H-imidazole) increases high-density lipoprotein cholesterol by targeting hepatic CYP3A.
T27460 GSK2324 GSK-2324,GSK 2324 FXR
GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.
T16844 Sarmazenil R-154513,Ro 15-3505 GABA Receptor
Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor with pro-convulsant properties and is used in the study of chronic hepatic encephalopathy (HE).
T7428 SBI-115 GPCR19
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T30577 BRD0418 BRD 0418,BRD-0418 Others
BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.
T60033 SBI993 Others
SBI993 is an analog of SBI-477 and can be used as a biomarker to confirm the expected action of MondoA target gene expression in vivo. SBI993 reduces muscle TAG levels and hepatic steatosis.
T4508 Glycyl-L-Histidyl-L-Lysine Others
Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production.
T27841 Lobeglitazone Sulfate CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang NOD
Lobeglitazone Sulfate（CKD-501 Sulfate） is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2...
T0299 Lactitol monohydrate D-Lactitol monohydrate Others
Lactitol monohydrate (D-Lactitol monohydrate) is a disaccharide analog of lactulose. It has been widely used to treat constipation and hepatic encephalopathy.
T19399 L-Ornithine L-aspartate Ornithine Aspartate Others
L-Ornithine L-aspartate (Ornithine Aspartate) lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis.
T37184 CX08005 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid Phosphatase
CX08005 is a protein tyrosine phosphatase 1B inhibitor. CX08005 reduces hepatic lipid accumulation and microcirculatory impairment associated with non-alcoholic fatty liver disease.
T36126 TMP-153
Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and choleste...
T40598 Norethindrone acetate 19-Norethindroneacetate Estrogen Receptor/ERR , Progesterone Receptor
Norethindrone acetate (19-Norethindroneacetate) is an oestrogen with inhibitory effects on adolescent menstruation and hepatic adenomas and is often used in combination with progestins in the study of endometriosis.
T14387 AZD9898 Leukotriene Receptor
AZD9898 is an inhibitor of leukotriene-C4 synthetase with an IC50 of 0.28 nM. AZD9898 can be used in studies about asthma. AZD9898 mitigates the GABA binding and hepatic toxicity signal.
T7295 Miridesap Ro63-8695,CPHPC,GSK2315698 Others
Miridesap (GSK2315698) is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. It also produces significant reduction of SAP from cerebrospinal fluid and visceral amyloid de...
T8929 BC1618 2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]- Mitophagy , Others , E1/E2/E3 Enzyme , AMPK
BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling. It promotes mitochondrial fission, promotes autophagy and imp...
T14875 Indocyanine green Cardiogreen,IC Green,Foxgreen Others
Indocyanine green (Cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and fo...
T9186 Ervogastat PF-06865571 Transferase
Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor. Ervogastat reduces steatosis and hepatic triglyceride levels in non-alcoholic steatohepatitis (NASH).
T35373L Bulevirtide (Myrcludex B) acetate HBV
Bulevirtide (Myrcludex B) acetate is a virion entry inhibitor which blocks the virion's hepatocyte pathway of entry, the hepatic sodium/taurocholate cotransporting polypeptide (NTCP) receptor. Bulevirtide (Myrcludex B) a...
T77245 Mannan Endogenous Metabolite
Mannan is isolated from algae, mushrooms, yeast and higher plants and acts as an immunomodulator.Mannan inhibits the pro-inflammatory activity of hepatic macrophages (M1 lineage) with protective effects against many live...
T25285 Dalvastatin RG-12561,RG 12561,RG12561 HMG-CoA Reductase
Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepatic HMG-CoA reductase with an IC50 value of 3.4 nmol / l. Dalvast...
TP2252 GLP-1 (9-36) amide Glucagon Receptor
antagonist at the human GLP-1 receptor
T23097 O-1602 O1602,O 1602 Cannabinoid Receptor , Calcium Channel
O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of cystitis.O-1602 promotes hepatic steatosis through GPR55 a...
T1386 Phenazopyridine hydrochloride Urodine,Pyridium,Phenazopyridine HCl Sodium Channel
Phenazopyridine hydrochloride (Pyridium) is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include nausea, interference with the oxygen-carrying capacity of red...
T0675 Topiramate RWJ 17021,McN 4853 Potassium Channel , Calcium Channel , GABA Receptor , Sodium Channel , GluR , Carbonic Anhydrase , iGluR
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepatic injury and largely when used in combination ...

Compounds

Anti-hepatic fibrosis agent 2
T83064
Synonym:
Target:
Oil Red O
TD0093
Synonym:
Target: Others
PTUPB
T12580
Synonym:
Target: COX, Epoxide Hydrolase
Pitavastatin lactone
T12490
Synonym:
Target: Others
TMPA
T13173
Synonym:
Target: Others, AMPK
LM10
T4410
Synonym:
Target: Others
Glymidine sodium
T31976
Synonym:
Target: Others
Climbazole
T1403
Synonym: BAY-e 6975
Target: Antibiotic, Antifungal
GSK4112
T5045
Synonym: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452
Target: Autophagy
Carbendazim
T3124
Synonym: Bavistin,Carbendazole,Mercarzole
Target: Antifungal
Cilostazol
T0462
Synonym: OPC 21,OPC 13013
Target: PDE, Autophagy
Primaquine diphosphate
T0850
Synonym: Primaquine phosphate,Primaquine bisphosphate
Target: Antibiotic, Parasite
SHR0302
T9195
Synonym: ARQ252
Target: Apoptosis, JAK
Torsemide
T1410
Synonym: AC-4464,JDL-464,Torasemide
Target: Na-K-Cl cotransporter
Mebrofenin
T8364
Synonym: SQ 26962
Target: Others
Framycetin sulfate
T2096
Synonym: Neomycin Sulphate B,Framycetin sulphate
Target: Antibacterial, Antibiotic
Valproic acid sodium salt
T1602
Synonym: Sodium Valproate
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, HDAC, Autophagy
Divalproex Sodium
T6474
Synonym: Valproate semisodium,Epival
Target: HDAC
Moexipril hydrochloride
T6595
Synonym: Moexipril HCl,RS-10085,SPM 925,CI-925
Target: Apoptosis, RAAS
SRI-37330
T60004
Synonym:
Target: Others
ATX inhibitor 5
T10409
Synonym:
Target: PDE
Hydronidone
T19694
Synonym: F351,F-351,F 351
Target: Others
Citiolone
T6807
Synonym: Thioxidrene,Citiolase
Target: Others
CDD3506
T13601
Synonym: 1-TRITYL-1H-IMIDAZOL-4-AMINE
Target: P450
Dehydroabiethylamine
T19783
Synonym: NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine
Target: P450, PDK
CDD3505
T13600
Synonym: 4-nitro-1-trityl-1H-imidazole
Target: P450
GSK2324
T27460
Synonym: GSK-2324,GSK 2324
Target: FXR
Sarmazenil
T16844
Synonym: R-154513,Ro 15-3505
Target: GABA Receptor
SBI-115
T7428
Synonym:
Target: GPCR19
BRD0418
T30577
Synonym: BRD 0418,BRD-0418
Target: Others
SBI993
T60033
Synonym:
Target: Others
Glycyl-L-Histidyl-L-Lysine
T4508
Synonym:
Target: Others
Lobeglitazone Sulfate
T27841
Synonym: CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang
Target: NOD
Lactitol monohydrate
T0299
Synonym: D-Lactitol monohydrate
Target: Others
L-Ornithine L-aspartate
T19399
Synonym: Ornithine Aspartate
Target: Others
CX08005
T37184
Synonym: 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid
Target: Phosphatase
TMP-153
T36126
Synonym:
Target:
Norethindrone acetate
T40598
Synonym: 19-Norethindroneacetate
Target: Estrogen Receptor/ERR, Progesterone Receptor
AZD9898
T14387
Synonym:
Target: Leukotriene Receptor
Miridesap
T7295
Synonym: Ro63-8695,CPHPC,GSK2315698
Target: Others
BC1618
T8929
Synonym: 2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-
Target: Mitophagy, Others, E1/E2/E3 Enzyme, AMPK
Indocyanine green
T14875
Synonym: Cardiogreen,IC Green,Foxgreen
Target: Others
Ervogastat
T9186
Synonym: PF-06865571
Target: Transferase
Bulevirtide (Myrcludex B) acetate
T35373L
Synonym:
Target: HBV
Mannan
T77245
Synonym:
Target: Endogenous Metabolite
Dalvastatin
T25285
Synonym: RG-12561,RG 12561,RG12561
Target: HMG-CoA Reductase
GLP-1 (9-36) amide
TP2252
Synonym:
Target: Glucagon Receptor
O-1602
T23097
Synonym: O1602,O 1602
Target: Cannabinoid Receptor, Calcium Channel
Phenazopyridine hydrochloride
T1386
Synonym: Urodine,Pyridium,Phenazopyridine HCl
Target: Sodium Channel
Topiramate
T0675
Synonym: RWJ 17021,McN 4853
Target: Potassium Channel, Calcium Channel, GABA Receptor, Sodium Channel, GluR, Carbonic Anhydrase, iGluR
1 2 3 4
Cat No. Product Name Synonyms Targets
T7992 4-Hydroxyflavanone NO Synthase
4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects
T3888 Scopolin Murrayin,Scopoloside Sirtuin
Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for...
T3858 Macranthoidin A Others
Macranthoidin A has anti-inflammation activity.
T0746 Orotic acid Vitamin B13,6-Carboxyuracil Nucleoside Antimetabolite/Analog , Dehydrogenase , Endogenous Metabolite
Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
T2718 Palmatine chloride Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T19081 1,3-Dithiane 1,3-Dithian,M-DITHIANE,1,3-Dithiacyclohexane Anti-infection , Endogenous Metabolite , Antibacterial
1,3-Dithiane (1,3-Dithian) is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon. 1,3-Dithiane is also a sulfur-containing Maillard reaction products found in boiled beef extracts.
T5S0802 Palmatine Berbericinine,Burasaine Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T3271 Orotic acid zinc Orotic acid zinc salt dihydrate,Zinc Orotate Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.
T3999 D(+)-Galactosamine hydrochloride D-Galactosamine HCl Others
D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.
T0700 Ursodeoxycholic acid UDCA,Ursodiol Potassium Channel , Endogenous Metabolite
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
T7064 Valproic Acid Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
T29078 Ursodeoxycholic acid sodium UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium FXR , Endogenous Metabolite , GPCR19
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...
TWA2417 Sodium taurocholate Taurocholate Sodium Others
Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and...
TN6751 1-HEXACOSANOL NPC1L1 , AMPK
Hexacosanol activates AMPK and hepatic autophagy and inhibits SREBP2, resulting in hypocholesterolemic activities and improvement of hepatic steatosis.
PDK0060 Pseudotropine Others
Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.
T2136 Geniposidic Acid Apoptosis , Others , Endogenous Metabolite
Geniposidic acid, an iridoid glucoside, used in therapy of jaundice, inflammation and hepatic disorders.
TN1599 Eburicoic acid Eburicoicacid,MFCD00238594,ZINC4655149 Antioxidant , TNF , NOS , NO Synthase , CCR , Immunology/Inflammation related
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in studies about anti-liver cancer.
TN1675 Gardenin B Apoptosis , ROS , Caspase , NO Synthase
Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .
T21383 D-Thyroxine Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine Others
D-Thyroxine (Dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles.
T5261 (E)-Oct-2-enoic acid trans-2-Octenoic acid,2-Octenoate,2-Octenoic acid Others , Endogenous Metabolite
(E)-Oct-2-enoic acid (2-Octenoate) is a normal organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally found in the urine and plasma.
T36831 9-Oxononanoic Acid 9-ONA Phospholipase , CPT
9-Oxononanoic Acid is an oxidized fatty acid, formed by the autoxidation of linoleic acid, which enhances phospholipase A2 (PLA2) activity and increases the production of thromboxane B2 in isolated human plasma.9-Oxonona...
T0799 Lactulose Duphalac,4-O-β-D-Galactopyranosyl-D-fructose,D-Lactulose,Lactulosum Others
Lactulose (Lactulosum) , a synthetic disaccharide , is used in the treatment of constipation and hepatic encephalopathy.
T3924 Astragaloside II Astrasieversianin VIII TGF-beta/Smad
Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, ...
T0687 Simvastatin MK-0733,MK 733 Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc...
TN2359 Iristectorigenin B Iristectrigenin B Liver X Receptor
Iristectorigenin B (Iristectrigenin B) is a potent hepatic X-receptor (LXR) modulator, a small molecule compound isolated from Belamcanda chinensis.Iristectrigenin B promotes the expression of ABCA264 and ABCG7 in macrop...
T75636 (E/Z)-Squalene (E/Z)-Super Squalene,(E/Z)-AddaVax
(E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production and induces apoptosis and necrosis in a concentration and time-dependent manner. (E/Z)-Squalene accumulates in the liver an...
T4916 D-Glucaric acid potassium D-Saccharic acid potassium salt,Glucosaccharic acid,Glucaric Acid Others , Endogenous Metabolite
D-Glucaric acid potassium (D-Saccharic acid potassium salt) is a compound formed from oxidizing sugars, which can be used to test for the presence of hepatic enzyme induction. Studies indicate that D-glucuronolactone deh...
T3414 Morroniside Apoptosis , MMP , Pyroptosis
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhib...
T4S0797 Berberine Berberin,Umbellatine Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T4713 Phosphorylcholine chloride calcium salt tetrahydrate Phosphocholine chloride calcium salt tet,CalciuM Phosphorylcholine Tetrahydrate Others , Endogenous Metabolite
Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the conc...
TCS1772 Dehydroabietic acid Dehydroabietate Antifection
1. Dehydroabietic acid (Dehydroabietate) (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma trigl...
TWO2727 Propane-1,2,3-triyl tripalmitate Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate Others , Endogenous Metabolite
Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a ...
T2909 Fraxetin 7,8-dihydroxy-6-methoxy coumarin Apoptosis , Others
Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a m...
T0186 Docetaxel trihydrate RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate Apoptosis , BCL , Microtubule Associated
Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor i...
T6S0221 Eriocitrin eriodictyol 7-rutinoside,Eriodictyol-7-O-Rutinoside,Eriodictioside,Eriodictyol glycoside Apoptosis , Carbonic Anhydrase
1. Eriocitrin (Eriodictyol-7-O-Rutinoside) is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of high-fat diet....
T5248 (R)-3-Hydroxybutanoic acid Others , Endogenous Metabolite
3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. B...
T5S0896 Loureirin A Akt , PI3K
Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...
T6S1917 Schisandrol B Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B P450 , Reactive Oxygen Species , Autophagy
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...
T5S0106 Peimisine Ebeiensine RAAS , AChR
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...
TN2063 Physalin B NSC-287088 Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD
Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B amel...
T20524 Lasiocarpine 7-Angelyleuropine,(-)-Lasiocarpine,Europine 7-angelate,AI3-51770
Lasiocarpine is a pyrrolizidine alkaloid, it has acute cytotoxicity in human and hepatic cell lines.
T30784 Cedrene AI3-51328,AI3 51328,AI351328
Cedrene can regulate hepatic steatosis via the cAMP-PKA pathway.
TMA1409 Cis-Mulberroside A TNF , NOS
cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage.
T38805 Euphol acetate
Euphol acetate, a triterpene found in Euphorbia broteri, has demonstrated inhibitory effects on the hepatic transport proteins known as organic anion-transporting polypeptide 1/3 (OATP1B1/3).
T28021 Meso-Dihydroguaiaretic acid
meso-Dihydroguaiaretic acid is an LXR-α antagonist, it inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.
T81521 Penispidin A
Penispidin A suppresses lipid accumulation in hepatic HepG2 cells.
TN3517 Bisacurone IL Receptor , IκB/IKK , TNF , NF-κB , ROS , Akt , PKC
Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressing hepatic oxidation and inflammation.
T11365 Ganodermanontriol Others
Ganodermanontriol, a sterol derived from Ganoderma lucidum, showcases hepatoprotective activity and possesses anti-inflammatory properties in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the upregulatio...
T11513 Gum arabic Arabic gum Others
Gum Arabic, a branched-chain, complex polysaccharide derived from A. Senegal, exhibits antioxidant properties and offers protection against experimental hepatic, renal, and cardiac toxicities. Additionally, it finds appl...
T10044 13-Oxo-9E,11E-octadecadienoic acid PPAR
13-Oxo-9E,11E-octadecadienoic acid, a potent PPARα activator derived from tomato juice and an isomer of 9-oxo-ODA, exhibits the ability to decrease plasma and hepatic triglyceride levels in obese diabetic mice[1].
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Natural Products

4-Hydroxyflavanone
T7992
Synonym:
Target: NO Synthase
Scopolin
T3888
Synonym: Murrayin,Scopoloside
Target: Sirtuin
macranthoidin A
T3858
Synonym:
Target: Others
Orotic acid
T0746
Synonym: Vitamin B13,6-Carboxyuracil
Target: Nucleoside Antimetabolite/Analog, Dehydrogenase, Endogenous Metabolite
Palmatine chloride
T2718
Synonym:
Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase
1,3-Dithiane
T19081
Synonym: 1,3-Dithian,M-DITHIANE,1,3-Dithiacyclohexane
Target: Anti-infection, Endogenous Metabolite, Antibacterial
Palmatine
T5S0802
Synonym: Berbericinine,Burasaine
Target: Indoleamine 2,3-Dioxygenase (IDO), AChR, AChE, Aurora Kinase
Orotic acid zinc
T3271
Synonym: Orotic acid zinc salt dihydrate,Zinc Orotate
Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite
D(+)-Galactosamine hydrochloride
T3999
Synonym: D-Galactosamine HCl
Target: Others
Ursodeoxycholic acid
T0700
Synonym: UDCA,Ursodiol
Target: Potassium Channel, Endogenous Metabolite
Valproic Acid
T7064
Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy
Ursodeoxycholic acid sodium
T29078
Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium
Target: FXR, Endogenous Metabolite, GPCR19
Sodium taurocholate
TWA2417
Synonym: Taurocholate Sodium
Target: Others
1-HEXACOSANOL
TN6751
Synonym:
Target: NPC1L1, AMPK
Pseudotropine
PDK0060
Synonym:
Target: Others
Geniposidic Acid
T2136
Synonym:
Target: Apoptosis, Others, Endogenous Metabolite
Eburicoic acid
TN1599
Synonym: Eburicoicacid,MFCD00238594,ZINC4655149
Target: Antioxidant, TNF, NOS, NO Synthase, CCR, Immunology/Inflammation related
Gardenin B
TN1675
Synonym:
Target: Apoptosis, ROS, Caspase, NO Synthase
D-Thyroxine
T21383
Synonym: Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine
Target: Others
(E)-Oct-2-enoic acid
T5261
Synonym: trans-2-Octenoic acid,2-Octenoate,2-Octenoic acid
Target: Others, Endogenous Metabolite
9-Oxononanoic Acid
T36831
Synonym: 9-ONA
Target: Phospholipase, CPT
Lactulose
T0799
Synonym: Duphalac,4-O-β-D-Galactopyranosyl-D-fructose,D-Lactulose,Lactulosum
Target: Others
Astragaloside II
T3924
Synonym: Astrasieversianin VIII
Target: TGF-beta/Smad
Simvastatin
T0687
Synonym: MK-0733,MK 733
Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy
Iristectorigenin B
TN2359
Synonym: Iristectrigenin B
Target: Liver X Receptor
(E/Z)-Squalene
T75636
Synonym: (E/Z)-Super Squalene,(E/Z)-AddaVax
Target:
D-Glucaric acid potassium
T4916
Synonym: D-Saccharic acid potassium salt,Glucosaccharic acid,Glucaric Acid
Target: Others, Endogenous Metabolite
Morroniside
T3414
Synonym:
Target: Apoptosis, MMP, Pyroptosis
Berberine
T4S0797
Synonym: Berberin,Umbellatine
Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy
Phosphorylcholine chloride calcium salt tetrahydrate
T4713
Synonym: Phosphocholine chloride calcium salt tet,CalciuM Phosphorylcholine Tetrahydrate
Target: Others, Endogenous Metabolite
Dehydroabietic acid
TCS1772
Synonym: Dehydroabietate
Target: Antifection
Propane-1,2,3-triyl tripalmitate
TWO2727
Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate
Target: Others, Endogenous Metabolite
Fraxetin
T2909
Synonym: 7,8-dihydroxy-6-methoxy coumarin
Target: Apoptosis, Others
Docetaxel trihydrate
T0186
Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate
Target: Apoptosis, BCL, Microtubule Associated
Eriocitrin
T6S0221
Synonym: eriodictyol 7-rutinoside,Eriodictyol-7-O-Rutinoside,Eriodictioside,Eriodictyol glycoside
Target: Apoptosis, Carbonic Anhydrase
(R)-3-Hydroxybutanoic acid
T5248
Synonym:
Target: Others, Endogenous Metabolite
Loureirin A
T5S0896
Synonym:
Target: Akt, PI3K
Schisandrol B
T6S1917
Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B
Target: P450, Reactive Oxygen Species, Autophagy
Peimisine
T5S0106
Synonym: Ebeiensine
Target: RAAS, AChR
Physalin B
TN2063
Synonym: NSC-287088
Target: Apoptosis, NF-κB, Akt, PI3K, Nrf2, NOD
Lasiocarpine
T20524
Synonym: 7-Angelyleuropine,(-)-Lasiocarpine,Europine 7-angelate,AI3-51770
Target:
Cedrene
T30784
Synonym: AI3-51328,AI3 51328,AI351328
Target:
cis-Mulberroside A
TMA1409
Synonym:
Target: TNF, NOS
Euphol acetate
T38805
Synonym:
Target:
meso-Dihydroguaiaretic acid
T28021
Synonym:
Target:
Penispidin A
T81521
Synonym:
Target:
Bisacurone
TN3517
Synonym:
Target: IL Receptor, IκB/IKK, TNF, NF-κB, ROS, Akt, PKC
Ganodermanontriol
T11365
Synonym:
Target: Others
Gum arabic
T11513
Synonym: Arabic gum
Target: Others
13-Oxo-9E,11E-octadecadienoic acid
T10044
Synonym:
Target: PPAR
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Recombinant Proteins

Species：
Human (48)
Mouse (15)
Rat (3)
Canine (2)
Cynomolgus (2)
Rhesus (2)
Expression System：
HEK293 (32)
E. coli (27)
Human Cells (9)
Baculovirus-Insect Cells (2)
Yeast (1)
in vitro E. coli expression system (1)
Tag：
His (26)
C-6His (6)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (6)
N-6His (5)
N-terminal 6xHis-tagged (4)
mFc (4)
hFc (3)
His,Trx (2)
C-Fc (2)
C-hFc (2)
Cat No. Product Name Species Expression System
TMPJ-00479 KHK Protein, Human, Recombinant (His) Human Human Cells
Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adren...
TMPY-00419 HEPACAM Protein, Human, Recombinant (His) Human HEK293
HEPACAM Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 24.5 kDa. Accession number: Q14CZ8-1
TMPJ-01058 ARG2 Protein, Human, Recombinant (His) Human E. coli
Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not found...
TMPH-02526 Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth...
TMPH-02529 ASGR2 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine uni...
TMPH-03248 ASGR1 Protein, Rat, Recombinant (His & Myc) Rat HEK293
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine uni...
TMPJ-01415 ANGPTL4 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migratio...
TMPY-04966 PCSK9 Protein, Human, Recombinant (D374Y, His) Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-00408 PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His) Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05131 PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-02778 ENPP2 Protein, Human, Recombinant (His) Human HEK293
ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-00463 ENPP2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-01442 DMBT1 Protein, Human, Recombinant (His) Human HEK293
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPY-01475 Jagged 1 Protein, Human, Recombinant (His) Human HEK293
Protein Jagged 1, also known as JAG1, JAGL1, and CD339, is a single-pass type I membrane protein that contains 1 DSL domain and 15 EGF-like domains. JAG1/Jagged 1 is widely expressed in adult and fetal tissues. The expre...
TMPH-02516 APOC3 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density...
TMPH-02420 APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar) Cynomolgus Yeast
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density...
TMPY-02909 ASGR2 Protein, Human, Recombinant (His) Human HEK293
ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively ...
TMPH-01578 KRT18 Protein, Human, Recombinant (His) Human HEK293
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT...
TMPH-01577 KRT18 Protein, Human, Recombinant (E. coli, His) Human E. coli
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT...
TMPY-02686 PON3 Protein, Human, Recombinant (S50N, His) Human Baculovirus-Insect Cells
PON3 was enriched in the mitochondria-associated membrane fraction of hepatocytes. PON3 deficiency resulted in impaired mitochondrial respiration, increased mitochondrial superoxide levels, and increased hepatic expressi...
TMPJ-00876 FAH Protein, Human, Recombinant (His) Human Human Cells
Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. ...
TMPY-00481 AKR1C4 Protein, Human, Recombinant (His) Human E. coli
Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ...
TMPK-00981 PSMP Protein, Human, Recombinant (hFc) Human HEK293
PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of live...
TMPH-02701 Haptoglobin Protein, Mouse, Recombinant (His) Mouse E. coli
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to preven...
TMPJ-00834 ACADM Protein, Human, Recombinant (His) Human E. coli
Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the m...
TMPH-01382 GCGR Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g...
TMPH-02675 GCGR Protein, Mouse, Recombinant (GST) Mouse E. coli
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g...
TMPJ-00805 Apolipoprotein E/APOE Protein, Mouse, Recombinant (His) Mouse Human Cells
Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and ca...
TMPK-00630 PSMP Protein, Mouse, Recombinant (hFc) Mouse HEK293
PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of live...
TMPH-01383 GCGR Protein, Human, Recombinant (His & Myc) Human HEK293
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g...
TMPJ-00366 GAS6 Protein, Human, Recombinant (hFc) Human Human Cells
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds...
TMPJ-01142 CDO1 Protein, Human, Recombinant (His) Human E. coli
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pan...
TMPJ-00365 GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signa...
TMPH-01003 ATG14 Protein, Human, Recombinant (His & Myc) Human E. coli
Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidyletha...
TMPY-01587 SULT2A1 Protein, Human, Recombinant (His) Human E. coli
Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotra...
TMPJ-00361 Endoglin Protein, Human, Recombinant (Trx & His) Human E. coli
Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, a...
TMPJ-00924 Decorin Protein, Mouse, Recombinant (His) Mouse Human Cells
Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a gua...
TMPY-00995 PCSK9 Protein, Rhesus, Recombinant (His) Rhesus HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-01565 PCSK9 Protein, Rat, Recombinant (His) Rat HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05029 INHBE Protein, Human, Recombinant (hFc) Human HEK293
INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to gen...
TMPY-05217 PCSK9 Protein, Mouse, Recombinant (mFc) Mouse HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05114 PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His), Biotinylated Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-01245 PCSK9 Protein, Mouse, Recombinant (His) Mouse HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-01140 ACOT13/THEM2 Protein, Human, Recombinant (His) Human E. coli
The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty ...
TMPY-05270 PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05199 PCSK9 Protein, Human, Recombinant (D374Y, mFc) Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05218 PCSK9 Protein, Human, Recombinant (mFc) Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPJ-00729 Haptoglobin Protein, Human, Recombinant (N-His) Human E. coli
Haptoglobin(HP) is a secreted protein which is a member of the peptidase S1 family of serine proteases. As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin ...
TMPJ-00730 Haptoglobin Protein, Human, Recombinant (C-His) Human Human Cells
Haptoglobin(HP) is a secreted protein which is a member of the peptidase S1 family of serine proteases. As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin ...
TMPY-04394 Glucokinase Protein, Human, Recombinant Human E. coli
Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in ...
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KHK Protein, Human, Recombinant (His)
TMPJ-00479
Species: Human
Expression System: Human Cells
HEPACAM Protein, Human, Recombinant (His)
TMPY-00419
Species: Human
Expression System: HEK293
ARG2 Protein, Human, Recombinant (His)
TMPJ-01058
Species: Human
Expression System: E. coli
Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02526
Species: Mouse
Expression System: E. coli
ASGR2 Protein, Mouse, Recombinant (His & Myc)
TMPH-02529
Species: Mouse
Expression System: E. coli
ASGR1 Protein, Rat, Recombinant (His & Myc)
TMPH-03248
Species: Rat
Expression System: HEK293
ANGPTL4 Protein, Mouse, Recombinant (hFc)
TMPJ-01415
Species: Mouse
Expression System: Human Cells
PCSK9 Protein, Human, Recombinant (D374Y, His)
TMPY-04966
Species: Human
Expression System: HEK293
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His)
TMPY-00408
Species: Human
Expression System: HEK293
PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05131
Species: Human
Expression System: HEK293
ENPP2 Protein, Human, Recombinant (His)
TMPY-02778
Species: Human
Expression System: HEK293
ENPP2 Protein, Cynomolgus, Recombinant (His)
TMPY-00463
Species: Cynomolgus
Expression System: HEK293
DMBT1 Protein, Human, Recombinant (His)
TMPY-01442
Species: Human
Expression System: HEK293
Jagged 1 Protein, Human, Recombinant (His)
TMPY-01475
Species: Human
Expression System: HEK293
APOC3 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02516
Species: Mouse
Expression System: E. coli
APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar)
TMPH-02420
Species: Cynomolgus
Expression System: Yeast
ASGR2 Protein, Human, Recombinant (His)
TMPY-02909
Species: Human
Expression System: HEK293
KRT18 Protein, Human, Recombinant (His)
TMPH-01578
Species: Human
Expression System: HEK293
KRT18 Protein, Human, Recombinant (E. coli, His)
TMPH-01577
Species: Human
Expression System: E. coli
PON3 Protein, Human, Recombinant (S50N, His)
TMPY-02686
Species: Human
Expression System: Baculovirus-Insect Cells
FAH Protein, Human, Recombinant (His)
TMPJ-00876
Species: Human
Expression System: Human Cells
AKR1C4 Protein, Human, Recombinant (His)
TMPY-00481
Species: Human
Expression System: E. coli
PSMP Protein, Human, Recombinant (hFc)
TMPK-00981
Species: Human
Expression System: HEK293
Haptoglobin Protein, Mouse, Recombinant (His)
TMPH-02701
Species: Mouse
Expression System: E. coli
ACADM Protein, Human, Recombinant (His)
TMPJ-00834
Species: Human
Expression System: E. coli
GCGR Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-01382
Species: Human
Expression System: E. coli
GCGR Protein, Mouse, Recombinant (GST)
TMPH-02675
Species: Mouse
Expression System: E. coli
Apolipoprotein E/APOE Protein, Mouse, Recombinant (His)
TMPJ-00805
Species: Mouse
Expression System: Human Cells
PSMP Protein, Mouse, Recombinant (hFc)
TMPK-00630
Species: Mouse
Expression System: HEK293
GCGR Protein, Human, Recombinant (His & Myc)
TMPH-01383
Species: Human
Expression System: HEK293
GAS6 Protein, Human, Recombinant (hFc)
TMPJ-00366
Species: Human
Expression System: Human Cells
CDO1 Protein, Human, Recombinant (His)
TMPJ-01142
Species: Human
Expression System: E. coli
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00365
Species: Human
Expression System: Human Cells
ATG14 Protein, Human, Recombinant (His & Myc)
TMPH-01003
Species: Human
Expression System: E. coli
SULT2A1 Protein, Human, Recombinant (His)
TMPY-01587
Species: Human
Expression System: E. coli
Endoglin Protein, Human, Recombinant (Trx & His)
TMPJ-00361
Species: Human
Expression System: E. coli
Decorin Protein, Mouse, Recombinant (His)
TMPJ-00924
Species: Mouse
Expression System: Human Cells
PCSK9 Protein, Rhesus, Recombinant (His)
TMPY-00995
Species: Rhesus
Expression System: HEK293
PCSK9 Protein, Rat, Recombinant (His)
TMPY-01565
Species: Rat
Expression System: HEK293
INHBE Protein, Human, Recombinant (hFc)
TMPY-05029
Species: Human
Expression System: HEK293
PCSK9 Protein, Mouse, Recombinant (mFc)
TMPY-05217
Species: Mouse
Expression System: HEK293
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His), Biotinylated
TMPY-05114
Species: Human
Expression System: HEK293
PCSK9 Protein, Mouse, Recombinant (His)
TMPY-01245
Species: Mouse
Expression System: HEK293
ACOT13/THEM2 Protein, Human, Recombinant (His)
TMPY-01140
Species: Human
Expression System: E. coli
PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated
TMPY-05270
Species: Human
Expression System: HEK293
PCSK9 Protein, Human, Recombinant (D374Y, mFc)
TMPY-05199
Species: Human
Expression System: HEK293
PCSK9 Protein, Human, Recombinant (mFc)
TMPY-05218
Species: Human
Expression System: HEK293
Haptoglobin Protein, Human, Recombinant (N-His)
TMPJ-00729
Species: Human
Expression System: E. coli
Haptoglobin Protein, Human, Recombinant (C-His)
TMPJ-00730
Species: Human
Expression System: Human Cells
Glucokinase Protein, Human, Recombinant
TMPY-04394
Species: Human
Expression System: E. coli
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Cat No. Product Name
L2193 Anti-Liver Cancer Compound Library

1816 compounds
1816 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L8700 Ferroptosis Compound Library

800 compounds
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；
L5510 Drug-induced Liver Injury (DILI) Compound Library

1040 compounds
A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening；

Libraries

Anti-Liver Cancer Compound Library
L2193
Compounds: 1816
Ferroptosis Compound Library
L8700
Compounds: 800
Drug-induced Liver Injury (DILI) Compound Library
L5510
Compounds: 1040
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