genistein

Genistein (NPI 031L) is a naturally occurring soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor, antioxidant, and anthelmintic properties, and also produces estrogen-like effects in the body.

Genistein 8-c-glucoside (G8CG), a natural glucoside isolated from the flowers of Lupinus luteus L., induces mitochondrial membrane depolarization and apoptosis.

Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range.

Genistein 7-O-beta-D-glucopyranoside-4'-O-[alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside] is a natural product

Genistein 7-O-glucuronide is a natural product for research related to life sciences. The catalog number is TN4125 and the CAS number is 38482-81-4.

8-(1,1-Dimethylallyl)genistein is a natural product for research related to life sciences. The catalog number is TN6335 and the CAS number is 651750-08-2.

3',5'-Diprenylgenistein is a useful organic compound for research related to life sciences and the catalog number is T126492.

6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria.

2'-Hydroxygenistein is a naturally occurring flavonoid with a wide range of antioxidant, anti-inflammatory, anticancer, and anti-endometrial hyperplasia potentials.2'-Hydroxygenistein is a inhibitor of a variety of enzymes, including indole-3-acetic acid oxidase, α-glucosidase, β-glucuronidase, and lysozyme.

5-O-Methylgenistein may show free radical scavenging activity, it also may have hepatoprotective property on the model of toxic hepatitis induced by carbon tetrachloride damage.

6-Methylgenistein is a natural product from Sophora dunnii.

6-Hydroxygenistein is an isoflavone compound identified in Baptisia hirsuta.

6-Hydroxygenistein-7-O-β-D-glucopyranoside (compound 2) is a glucopyranoside extracted from Pueraria flower. Isoflavonoids from Pueraria flower are potential anti-inflammatory agents for microglial cells and can inhibit the production of NO.

Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties.

Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities

Sophoricoside (Genistein sophoricoside) is effective against inflammation and can reduce the GPT.

Thevetiaflavone (2-Genistein-5-methyl ether) is a natural flavonoid from Wikstroemia indica that inhibits the leakage of lactate dehydrogenase from the cytoplasm and increases cell viability.

(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein. (±)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM). (±)-Equol is also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies.

G-4'G-7S is an endogenous metabolite of genistein that can be used for research on estrogenic activity [1].