Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Src
    (13)
  • Apoptosis
    (5)
  • PDGFR
    (4)
  • CDK
    (3)
  • EGFR
    (3)
  • FGFR
    (3)
  • JAK
    (3)
  • VEGFR
    (3)
  • 5-HT Receptor
    (2)
  • Others
    (3)
Filter
Search Result
Results for "

fyn

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    29
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    2
    TargetMol | Peptide_Products
  • Recombinant Protein
    2
    TargetMol | Recombinant_Protein
  • Antibody Products
    3
    TargetMol | Antibody_Products
Saracatinib
AZD0530
T6078379231-04-6
Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
CHIR-124
CHIR124, CHIR 124
T6350405168-58-3
CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2 4.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
ARN25068
T613602649882-80-2In house
ARN25068 is a potent inhibitor of GSK-3β, FYN, and DYRK1A protein kinases, exerting its activity in the sub-micromolar range. This compound effectively addresses tau hyperphosphorylation [1].
  • Inquiry Price
6-8 weeks
Size
QTY
Doramapimod
BIRB 796
T6277285983-48-4
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
TG 100572 Hydrochloride
T13156L867331-64-4In house
TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively).
  • Inquiry Price
6-8 weeks
Size
QTY
Pyridone 6
Janus-Associated Kinase Inhibitor I, JAK Inhibitor I, JAK I inhibitor, CMP 6
T3080457081-03-7
Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.
  • Inquiry Price
Size
QTY
azd-7762
AZD7762
T6093860352-01-8
AZD-7762, an effective and specific inhibitor of Chk1(IC50=5 nM), is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.
  • Inquiry Price
Size
QTY
PP1
EI 275, AGL 1872
T6196172889-26-8
PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck Fyn is 5 nM 6 nM, respectively.
  • Inquiry Price
Size
QTY
PP2
AG 1879, AGL 1879
T6266172889-27-9
PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck Fyn (IC50:4 5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.
  • Inquiry Price
Size
QTY
SAX-187
WAY 181187, WAY181187
T3183554403-49-5
SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Rigosertib sodium
Rigosertib, Estybon, ON-01910
T5818592542-60-4
Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
ON123300
T69201357470-29-1
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4 Ark5 PDGFRβ FGFR1 RET Fyn (IC50: 3.9 5 26 26 9.2 11 nM).
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
TG 100572
T13156867334-05-2
TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively).
  • Inquiry Price
6-8 weeks
Size
QTY
TG 100801 Hydrochloride
T13157L1018069-81-2
TG 100801 Hydrochloride is a prodrug to treat age-related macular degeneration. TG 100572 is a inhibitor of multi-targeted kinase(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src,
  • Inquiry Price
1-2 weeks
Size
QTY
A-770041
A770041, A 770041
T14074869748-10-7
A-770041 is an orally active and selective Lck inhibitor that inhibits concanavalin A-stimulated IL-2 production in whole blood and prevents cardiac allograft rejection. A-770041 reduces pulmonary fibrosis by inhibiting TGF-β production in regulatory T cells.
  • Inquiry Price
7-10 days
Size
QTY
Infigratinib phosphate
NVP-BGJ398 phosphate, BGJ-398 phosphate
T163641310746-10-1
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
  • Inquiry Price
6-8 weeks
Size
QTY
Rigosertib
ON-01910
T16750592542-59-1
Rigosertib (ON-01910) is a selective, non-ATP-competitive PLK1 inhibitor (IC50: 9 nM) and multi-kinase inhibitor. As a selective anti-cancer agent, Rigosertib induces apoptosis by inhibiting the PI3 kinase Akt pathway, promotes histone H2AX phosphorylation, and induces G2 M arrest in the cell cycle.
  • Inquiry Price
Size
QTY
1-NM-PP1
PP1 Analog II, 1 nM-PP1
T2153221244-14-0
1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
  • Inquiry Price
Size
QTY
ST1936
ST 1936
T233961210-81-7
ST1936 (ST 1936 oxalate) is a selective and highly potent 5-HT6 receptor agonist that inhibits human 5-HT6, 5-HT7 and 5-HT2B receptors by fully activating cloned human 5-HT6 receptors. body to stimulate cAMP, Ca2+, ERK1 2 and Fyn kinase.
  • Inquiry Price
6-8 weeks
Size
QTY
BMS-243117
UNII-MBE6KWV0QI, MBE6KWV0QI, CHEMBL67237
T30508225521-80-2
BMS-243117 is an effective selective LCK inhibitor with good cell activity (IC(50)=1.1 microM) and inhibition of T cell proliferation, which has great potential for therapeutic immunosuppression and the treatment of diseases such as rheumatoid arthritis a
  • Inquiry Price
6-8 weeks
Size
QTY
Streptochlorin
T36713120191-51-7
Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. SF2583 that has diverse biological activities, including antiangiogenic, antiproliferative, and anti-allergic properties. It inhibits TNF-α-induced NF-κB transcriptional activity and decreases proliferation of human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 5 to 20 μM. Streptochlorin (12 μg/ml) decreases viability of, as well as induces apoptosis and increases the production of reactive oxygen species (ROS) in, Hep3B human hepatocellular carcinoma cells. It does not induce cytotoxicity in RBL-2H3 mast cells at concentrations up to 100 μM. Streptochlorin prevents degranulation in antigen-stimulated mast cells, as well as inhibits Syk kinase and the Src family kinases LYN and Fyn and reduces the secretion of TNF-α and IL-4 induced by dinitrophenyl-human serum album (DNP-HSA) in RBL-2H3 mast cells. It also decreases swelling and reduces scratching behavior in a mouse model of allergic dermatitis induced by dinitrofluorobenzene (DNFB).
  • Inquiry Price
Size
QTY
EPQpYEEIPIYL
T38965147612-86-0
EPQpYEEIPIYL, a phosphopeptide, is a ligand for the Src homology 2 (SH2) domain, activating Src family members such as Lck, Hck, and Fyn through binding interactions with SH2 domains.
  • Inquiry Price
4-6 weeks
Size
QTY
1-naphthyl pp1
1-NA-PP 1
T3935221243-82-9
1-Naphthyl PP1 (1-NA-PP 1) is a selective Src inhibitor, targeting v-Src and c-Fyn, c-Abl, CDK2, and CAMK II with IC50 values of 1.0, 0.6, 0.6, 18, and 22 μM, respectively.
  • Inquiry Price
Size
QTY
BAY 61-3606
Syk inhibitor IV
T4263732983-37-8
BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.
  • Inquiry Price
Size
QTY