fx-1

FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 μM. FX-11 can activate PKM2 (pyruvate kinase M2). FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor activity during xenotransplantation of lymphoma and pancreatic cancer.

FX-171-C is a non-competitive deubiquitinase inhibitor with an IC50 of 1.4 µM.

FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).

FX-909 is a covalent peroxisome proliferator-activated receptor gamma ( PPARG ) inverse agonist. FX-909 can be used for the research of cancer .

FX-06 (Fibrin-derived peptide Bβ15-42) is derived from the fibrin Bbeta chain and interacts with VE-cadherin to inhibit leukocyte transmigration while initiating VE-cadherin-mediated signaling pathways. This compound is utilized in researching ischemia reperfusion injury and Dengue shock syndrome (DSS) [1] [2] [4].