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  • Inhibitors & Agonists
    27
    TargetMol | Inhibitors_Agonists
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Questiomycin A derivatives 12
T67711 In house
Questiomycin A derivatives 12 is a Questiomycin A derivative.
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Questiomycin A derivatives 13
T67712 In house
Questiomycin A derivatives 13 is a Questiomycin A derivative.
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Questiomycin A derivatives 14
T67713 In house
Questiomycin A derivatives 14 is a Questiomycin A derivative.
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Questiomycin A derivatives 18 TFA
T67717L In house
Questiomycin A derivatives 18 TFA is A Questiomycin A derivative with antibacterial and anticancer activity and inhibition of the expression of the cell-protective ER chaperone protein GRP78.
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6-8 weeks
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AhR Ligand-Linker Conjugates 1
E3 Ligase Ligand-Linker Conjugates 57
T17364
AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be used in the development of SNIPER[1].
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CCK2R Ligand-Linker Conjugates 1
T177271452145-13-9
CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].
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cIAP1 Ligand-Linker Conjugates 11 Hydrochloride
E3 ligase Ligand-Linker Conjugates 33 Hydrochloride
T178841239866-59-1
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound comprising an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker, mainly used in the development of SNIPERs for targeted protein degradation[1].
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cIAP1 Ligand-Linker Conjugates 11
E3 ligase Ligand-Linker Conjugates 33
T178851239943-19-1
cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in the development of SNIPERs[1], allowing for the targeted degradation of proteins.
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cIAP1 Ligand-Linker Conjugates 15 hydrochloride
E3 ligase Ligand-Linker Conjugates 34 hydrochloride
T178861225383-36-7
cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker, useful in the development of SNIPERs [1].
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cIAP1 Ligand-Linker Conjugates 15
E3 ligase Ligand-Linker Conjugates 34
T178871225433-96-4
cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1].
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cIAP1 Ligand-Linker Conjugates 14
E3 ligase Ligand-Linker Conjugates 36
T178891351169-40-8
cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1].
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cIAP1 Ligand-Linker Conjugates 12
E3 ligase Ligand-Linker Conjugates 38
T178922095244-52-1
cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creating SNIPERs[1].
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cIAP1 Ligand-Linker Conjugates 1
E3 ligase Ligand-Linker Conjugates 41
T178952357114-75-9
cIAP1 Ligand-Linker Conjugates 1 is composed of an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 1, is particularly useful in the development of SNIPERs[1].
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cIAP1 Ligand-Linker Conjugates 13
E3 ligase Ligand-Linker Conjugates 43
T17897
cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1].
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cIAP1 Ligand-Linker Conjugates 10
E3 ligase Ligand-Linker Conjugates 47
T17901
cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROTAC linker. SNIPERs can be developed using cIAP1 Ligand-Linker Conjugates 10.
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VHL Ligand-Linker Conjugates 15
E3 Ligase Ligand-Linker Conjugates 56
T179082375564-62-6
VHL Ligand-Linker Conjugates 15 is a chemical compound that combines a VHL ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is specifically designed for the creation of PROTACs[1].
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ERRα Ligand-Linker Conjugates 1
T17941
ERRα Ligand-Linker Conjugates 1 refers to a chemical compound that consists of a ligand targeting estrogen-related receptor alpha (ERRα), and a PROTAC linker that facilitates the recruitment of E3 ligases MDM2. It finds utility in the synthesis of a range of PROTACs, including one known as PROTAC ERRalpha Degrader-1. With its capability to induce degradation of ERRα, PROTAC ERRalpha Degrader-1 functions as an ERRα degrader[1].
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VHL Ligand-Linker Conjugates 17
T18873
VHL Ligand-Linker Conjugates 17 are chemical compounds that consist of a VHL ligand specialized for the E3 ubiquitin ligase, as well as a PROTAC linker. These conjugates are utilized in the synthesis of various PROTACs, including the notable ARD-266. ARD-266 is an exceptionally effective androgen receptor (AR) PROTAC degrader[1].
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cIAP1 Ligand-Linker Conjugates 16
cIAP1 Ligand-Linker Conjugates 16
T396092143956-63-0
cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs.
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TSPO Ligand-Linker Conjugates 1
T74571
TSPO Ligand-Linker Conjugates 1, comprising a translocator protein (TSPO) ligand and a linker, is instrumental in synthesizing mitochondria-targeting autophagy-targeting chimera (AUTAC). This compound binds TSPO on the outer mitochondrial membrane (OMM), facilitating the degradation of malfunctioning mitochondria and proteins through mitophagy, thereby enhancing mitochondrial function. It holds potential applications in research related to mitochondrial dysfunction, encompassing neurodegenerative diseases, cancer, and diabetes [1].
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Rivulariapeptolides 1155
T75648
Rivulariapeptolides 1155 is a potent serine protease inhibitor with inhibitory concentrations (IC50s) of 41.84 nM, 4.94 nM, and 56.54 nM against chymotrypsin, elastase, and proteinase K, respectively [1].
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Rivulariapeptolides 1185
T75649
Rivulariapeptolides 1185, a highly potent and selective serine protease inhibitor, exhibits IC50 values of 13.17 nM for chymotrypsin, 23.59 nM for elastase, and 55.26 nM for proteinase K [1].
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Rivulariapeptolides 1121
T75650
Rivulariapeptolides 1121 is a potent and selective serine protease inhibitor, demonstrating IC50 values of 35.52 nM for chymotrypsin, 13.24 nM for elastase, and 48.05 nM for proteinase K [1].
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BK60106
BK 60106
T78982
BK60106 is a selective inhibitor of the transmembrane protein CD99, which causes cell death in Ewing Sarcoma cells by directly binding to the extracellular structural domain of CD99.
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