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(2)
By Target- Ephrin Receptor
- Apoptosis(1)
- Autophagy(1)
- Bcr-Abl(1)
- Src(1)
- c-Kit(1)
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Results for "
epha 2
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Recombinant Protein2
Dasatinib monohydrate
BMS-354825 Monohydrate
T1448L863127-77-9
Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
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