en4

EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis.

EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).

EN460 is a selective inhibitor of Endoplasmic Reticulum Oxidase 1 (ERO1α), inhibiting ERO1L-mediated gene silencing and cell migration, and PDAC invasion.

XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties.

SEN461 is a wnt inhibitor.

EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-κB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be used to study leukemia.

N-1H-imidazo[4,5d ]pyridazin-7-yl benzamideN4-Benzoyl-2-aza-3'-deazaadenine is a Heterocyclic Compound - Purine; Intermediates and Building Blocks - Nucleoside bases.

Tween 40 is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

(-)-Verbenone is a naturally occurring terpene found in the leaves of Suregada zanzibariensis Verdc.Verbenone has anti-aggregation pheromone effects and interrupts the attraction of bark beetles to its aggregation pheromone.

Terpinen-4-ol (4-Carvomenthenol) is a natural compound derived from Pimpinella yunnanensis.

1,1-Dioxo-2,3-dihydrothiochromen-4-one ,with CAS No. 19446-96-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1,1-Dioxo-2,3-dihydrothiochromen-4-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(Nz)-n-(6-fluoro-2,3-dihydrothiochromen-4-ylidene)hydroxylamine ,with CAS No. 50596-11-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (Nz)-n-(6-fluoro-2,3-dihydrothiochromen-4-ylidene)hydroxylamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Fluoro-2,3-dihydro-4H-thiochromen-4-one 1,1-dioxide ,with CAS No. 21243-22-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Fluoro-2,3-dihydro-4H-thiochromen-4-one 1,1-dioxide provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6,6-Dimethyl-3-(methylthio)-4,5,6,7-tetrahydrobenzo[c]thiophen-4-one oxime ,with CAS No. 175202-71-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6,6-Dimethyl-3-(methylthio)-4,5,6,7-tetrahydrobenzo[c]thiophen-4-one oxime provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Benzo[c]thiophen-4(5H)-one, 6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)- ,with CAS No. 882270-24-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Benzo[c]thiophen-4(5H)-one, 6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)- provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-HYDROXY-4H-CHROMEN-4-ONE, with CAS No. 3952-69-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-HYDROXY-4H-CHROMEN-4-ONE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-AZA-TRICYCLO[4.2.1.0(2,5)]NON-7-EN-4-ONE, with CAS No. 14735-70-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-AZA-TRICYCLO[4.2.1.0(2,5)]NON-7-EN-4-ONE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-(2,3-Dihydro-1H-inden-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ,with CAS No. 1252793-57-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-(2,3-Dihydro-1H-inden-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1,2,3,5,6,7-Hexahydro-s-indacen-4-amine ,with CAS No. 63089-56-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1,2,3,5,6,7-Hexahydro-s-indacen-4-amine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-(4-Hydroxyphenyl)-2-methylhept-2-en-4-one is a useful organic compound for research related to life sciences and the catalog number is T123873.

Vobasine N4-oxide is a useful organic compound for research related to life sciences. The catalog number is T124736 and the CAS number is 51666-18-3.

S-Dihydrodaidzein ((3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one) is an enantiomer of dihydrodaidzein which is involved in equol biosynthesis in a lactic acid bacterium, Lactococcus sp. strain.

Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase.

Funapide (TV 45070) is a potent Sodium Channel Nav1.7 inhibitor with potential anti-inflammatory activity for the treatment of erythema gangrenosum, musculoskeletal pain, knee osteoarthritis, and postherpetic nerves.