dpn

estrogen receptor (ER) β agonist

DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .

NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH).

NAD sodium (β-DPN sodium) is distributed across all human cells, involved in thousands of biochemical reactions, and is an essential coenzyme in the body.

NAD+ lithium (β-DPN lithium) is the lithium salt form of nicotinamide adenine dinucleotide. This coenzyme plays a crucial role in redox reactions and can directly or indirectly influence various key cellular functions, such as metabolic pathways, DNA repair, chromatin remodeling, cell aging, and immune cell functions.

NADase is a biochemical reagent utilized as a biological material or organic compound in life science research.

DPNB-ABT 594 is a nitrobenzyl-caged ABT 594, a selective α4β2 nAChR agonist. One-photon uncaging evokes large inward currents and Ca2+transients on cell bodies and dendrites of medial habenular neurons in mouse brain slices. Two-photon uncaging induces fast nAChR-mediated currents. Photolyzed with high quantum yield of 0.20. Effective photolysis occurs using one- or two-photon excitation; one-photon uncaging requires illumination at 410 nm for 1.5-3 ms; two-photon uncaging requires illumination with appropriate two photon pulse laser at 710 nm for ~2 ms.

DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates nAChRs containing α4β2 subunits over the α7 subunit. It is utilized to map the distribution of nAChRs on medial habenula (MHb) neurons, thereby facilitating a deeper understanding of nAChR-mediated Ca2+ signaling in the MHb [1].

Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.

PC SPDP-NHS carbonate ester is a cleavable linker compound used in the synthesis of antibody-drug conjugates (ADCs) [1].

UDP-N-acetyl-D-Glucosamine is a natural nucleotide sugar that is used by glycosyltransferases to transfer N-acetyl-D-glucosamine residues to substrates.1It is an important component of antibiotic biosynthesis pathways in fungi and lipopolysaccharide production in bacteria.2,3 1.Roseman, S.Reflections on glycobiologyJ. Biol. Chem.276(45)41527-41542(2001) 2.Kudo, F., and Eguchi, T.Biosynthetic genes for aminoglycoside antibioticsJ. Antibiot. (Tokyo)62(9)471-481(2009) 3.Mulrooney, E.F., Poon, K.K., McNally, D.J., et al.Biosynthesis of UDP-N-acetyl-L-fucosamine, a precursor to the biosynthesis of lipopolysaccharide in Pseudomonas aeruginosa serotype O11J. Biol. Chem.280(20)19535-19542(2005)

Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.

Ac-YVAD-pNA, a specific substrate for Caspase-1, serves to detect Caspase-1 activity, a crucial mediator of inflammatory processes [1] [2].

UDP-GlcNAc is a fundamental component and precursor of bacterial peptidoglycan. Additionally, UDP-GlcNAc acts as an agonist for the P2Y14 receptor, which can inhibit the formation of cAMP.

α-Viniferin known as 2-arylbenzofuran flavonoids, that are inhibitors of prostaglandin H2 synthetase. α-Viniferin has anti-Alzheimer's disease, anti-tuberculosis, anti-tumor, anti-inflammation, anti-diabetes and other pharmacological activitie

Ac-VDQQD-pNA serves as a substrate for Caspase 2, which cleaves it to yield the yellow compound pNA (p-nitroaniline).

Deaminocozymase also known as Nicotinamide-hypoxanthine dinucleotide, is a biochemical.